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Triploid and pentaploid breeding is of great importance in agricultural production, but it is not always easy to obtain double ploidy parents. However, in fishes, chromosome ploidy is diversiform, which may provide natural parental resources for triploid and pentaploid breeding. Both tetraploid and hexaploid exist in Schizothorax fishes, which were thought to belong to different subfamilies with tetraploid Percocypris fishes in morphology, but they are sister genera in molecule. Fortunately, the pentaploid hybrid fishes have been successfully obtained by hybridization of Schizothorax wangchiachii (♀, 2n = 6X = 148) × Percocypris pingi (♂, 2n = 4X = 98). To understand the genetic and morphological difference among the hybrid fishes and their parents, four methods were used in this study: morphology, karyotype, red blood cell (RBC) DNA content determination and inter-simple sequence repeat (ISSR). In morphology, the hybrid fishes were steady, and between their parents with no obvious preference. The chromosome numbers of P. pingi have been reported as 2n = 4X = 98. In this study, the karyotype of S. wangchiachii was 2n = 6X = 148 = 36m + 34sm + 12st + 66t, while that the hybrid fishes was 2n = 5X = 123 = 39m + 28sm + 5st + 51t. Similarly, the RBC DNA content of the hybrid fishes was intermediate among their parents. In ISSR, the within-group genetic diversity of hybrid fishes was higher than that of their parents. Moreover, the genetic distance of hybrid fishes between P. pingi and S.wangchiachii was closely related to that of their parental ploidy, suggesting that parental genetic material stably coexisted in the hybrid fishes. This is the first report to show a stable pentaploid F1 hybrids produced by hybridization of a hexaploid and a tetraploid in aquaculture.
The aim of the study was to investigate any association between extrauterine growth restriction (EUGR) and intestinal flora of <30-week-old preterm infants. A total of 59 preterm infants were assigned to EUGR (n=23) and non-EUGR (n=36) groups. Intestinal bacteria were compared by using high-throughput sequencing of bacterial rRNA. The total abundance of bacteria in 344 genera (7568 v. 13,760; P<0.0001) and 456 species (10,032 v. 18,240; P<0.0001) was significantly decreased in the EUGR group compared with the non-EUGR group. After application of a multivariate logistic model and adjusting for potential confounding factors, as well as false-discovery rate corrections, we found four bacterial genera with higher and one bacterial genus with lower abundance in the EUGR group compared with the control group. In addition, the EUGR group showed significantly increased abundances of six species (Streptococcus parasanguinis, Bacterium RB5FF6, two Klebsiella species and Microbacterium), but decreased frequencies of three species (one Acinetobacter species, Endosymbiont_of_Sphenophorus_lev and one Enterobacter_species) compared with the non-EUGR group. Taken together, there were significant changes in the intestinal microflora of preterm infants with EUGR compared to preterm infants without EUGR.
Alanyl-glutamine (Ala-Gln), a highly soluble and stable glutamine dipeptide, is known to improve gut integrity and function. The aim of this study was to evaluate whether dietary Ala-Gln supplementation could improve growth performance, intestinal development and digestive-absorption function in weaned piglets. A total of 100 purebred Yorkshire piglets weaned at 21 days of age were assigned randomly to four dietary treatment groups and fed a basal diet (control group) or a basal diet containing 0.15%, 0.30% and 0.45% Ala-Gln, respectively. Compared with the control group, piglets fed the Ala-Gln diets had higher average daily gain and lower feed : gain and diarrhea rate (P < 0.05). Moreover, dietary Ala-Gln supplementation increased villous height and villous height : crypt depth ratio in duodenum and jejunum (P < 0.05), as well as the activities of maltase and lysozyme in jejunum mucosa (P < 0.05). In addition, a decrease in serum diamine oxidase activity and crypt depth in duodenum and jejunum was observed in piglets fed the Ala-Gln diets (P < 0.05). Serum cytosolic phospholipase A2 (cPLA2) concentration and gene expression of cPLA2, Na+-dependent glucose transporter 1, glucose transporter 2 and peptide transporter 1 in jejunum were increased by feeding Ala-Gln diets relative to control diet (P < 0.05). These results indicated that feeding Ala-Gln diet has beneficial effects on the growth performance of weaned piglets, which associated with maintaining intestinal morphology and digestive-absorption function.
Adults with congenital heart disease face psychological challenges although an understanding of depression vs. anxiety symptoms is unclear. We analyzed the prevalence of elevated symptoms of anxiety and depression and explored associations with demographic and medical factors as well as quality of life.
Adults with congenital heart disease enrolled from an outpatient clinic completed the Hospital Anxiety and Depression Scale and two measures of quality of life: the Linear Analogue Scale and the Satisfaction with Life Scale. Medical data were obtained by chart review.
Of 130 patients (median age = 32 years; 55% female), 55 (42%) had elevated anxiety symptoms and 16 (12%) had elevated depression symptoms on subscales of the Hospital Anxiety and Depression Scale. Most patients with elevated depression symptoms also had elevated anxiety symptoms (15/16; 94%). Of 56 patients with at least one elevated subscale, 37 (66%) were not receiving mental health treatment. Compared to patients with 0 or 1 elevated subscales, patients with elevations in both (n=15) were less likely to be studying or working (47% vs. 81%; p=0.016) and reported lower scores on the Linear Analogue Scale (60 vs. 81, p<0.001) and the Satisfaction with Life Scale (14 vs. 28, p<0.001).
Among adults with congenital heart disease, elevated anxiety symptoms are common and typically accompany elevated depressive symptoms. The combination is associated with unemployment and lower quality of life. Improved strategies to provide psychosocial care and support appropriate engagement in employment are required.
Muons produced by the Bethe–Heitler process from laser wakefield accelerated electrons interacting with high
materials have velocities close to the laser wakefield. It is possible to accelerate those muons with laser wakefield directly. Therefore for the first time we propose an all-optical ‘Generator and Booster’ scheme to accelerate the produced muons by another laser wakefield to supply a prompt, compact, low cost and controllable muon source in laser laboratories. The trapping and acceleration of muons are analyzed by one-dimensional analytic model and verified by two-dimensional particle-in-cell (PIC) simulation. It is shown that muons can be trapped in a broad energy range and accelerated to higher energy than that of electrons for longer dephasing length. We further extrapolate the dependence of the maximum acceleration energy of muons with the laser wakefield relativistic factor
and the relevant initial energy
. It is shown that a maximum energy up to 15.2 GeV is promising with
on the existing short pulse laser facilities.
Vessel flexure can be triggered naturally by surgical operation, heart pulsation and body movement. It may affect the mechanical behavior of the stent and the existence of a stent may in turn cause vessel injury. In the present study, the finite element method is employed to study the interaction between stent and vessel during vessel flexure. Two- and four-link stents made of stainless steel 316L and magnesium alloy WE43 are considered. Results indicate that longitudinal deformation of the stent can be caused by vessel flexure, and the higher levels of stress exist in the link struts. The existence of the stent could induce significant stress concentration and straightened deformation on vessel wall in the course of vessel flexure. Stents with more links or made of harder materials show greater anti-deformation capability, thus inducing a more severe stress concentration and straightened deformation on the vessel wall. The bending direction also affects the mechanical performance of the vessel-stent system. The results obtained could provide useful information for better stent designs and clinical decisions.
Monolithic large-aperture diffraction grating tiling is desired to increase the output capability of multi-kilojoule petawatt laser facilities. However, the wavefront errors of input pulse and gratings will degrade the focal spot quality and the compressibility of the output pulse. In this work, the effects of wavefront error of input pulse, deformation and wave aberration of the grating for the large-aperture tiled-grating compressor are investigated theoretically. A series of numerical simulations are presented to discuss the changing trends of focal spot energy caused by wavefront error of input pulse and obtain the error tolerance for specific goals. The influences of coating stress and the wave aberration of holographic exposure gratings on the diffraction wavefront are also discussed. Some advice is proposed for improving the performance of large-aperture tiled-grating. This work paves the way for the design of practical large-aperture tiled-grating compressor for ultrahigh intensity laser facilities in the future.
We present first results from pilot observations using a phased array feed (PAF) mounted on the Parkes 64-m radio telescope. The observations presented here cover a frequency range from 1 150 to 1 480 MHz and are used to show the ability of PAFs to suppress standing wave problems by a factor of ~10, which afflict normal feeds. We also compare our results with previous HIPASS observations and with previous H i images of the Large Magellanic Cloud. Drift scan observations of the GAMA G23 field resulted in direct H i detections at z = 0.0043 and z = 0.0055 of HIPASS galaxies J2242-30 and J2309-30. Our new measurements generally agree with archival data in spectral shape and flux density, with small differences being due to differing beam patterns. We also detect signal in the stacked H i data of 1 094 individually undetected galaxies in the GAMA G23 field in the redshift range 0.05 ⩽ z ⩽ 0.075. Finally, we use the low standing wave ripple and wide bandwidth of the PAF to set a 3σ upper limit to any positronium recombination line emission from the Galactic Centre of <0.09 K, corresponding to a recombination rate of <3.0 × 1045 s−1.
Huang et al have classified pulsars into two types according to the role played by the superfluid neutron vortexes in the interior of neutron stars. They have also presented the formule of P for these two types of pulsars. In this short remark, we shall compare the conclusions about the evolutions of these two types of pulsars with the observational distributions. The consequences obtained are summarized as follws.
Our calculations show that the cross section of the inverse Compton scattering in strong magnetic fields may be larger than that of Thompson scattering by sevaral orders of magnitude in the case of polar cap surface of pulsars. We can also see that when the energy of e± exceeds a certain value, their energy loss caused by the inverse Compton scattering may be larger than the energy gain from electric field in the inner gap, which implies that the e± could not be accelerated to γ = 106. Meanwhile, the electrostatic forces acting on the electrons will be balanced by the radiative pressure if temperature T > 108 K.
It is beleived that the surface temperarure for most of pulsars is less than 106 K, in that case the ions of iron can not be emitted from the surface of pulsars. However, the temperarure at the polar cap can be increased to 3×106 through the bombardment of electrons to the polar cap according to R-S model. This quasi-equilibrium state by self-regulating must make the coherent radio emission unstable on the contrary.
In the former work (Xia, Deng and Zhou, 1986), we have showed by two- point correlation analysis that more luminous galaxies cluster stronger. Now we present the result of cross-correlation analysis for galaxies with different luminosity. This analysis supplies information about the relations between the distributions of galaxies with different luminosity. The analyses are based on the data given by CfA survey and have made the same corrections as in the former work. The samples are divided into three subgroups in absolute magnitude ranges: a) −21–22, b) −20–21 and c)−19–20. We make the cross-correlation analysis for each two subgroups. Fig. 1 gives the obtained cross-correlation function ξc(r) and Fig. 2 shows the log ξc(r)-log r diagram, the straight lines in Fig. 2 are given by linear regression. These results show that the two brightest subgroups have the strongest correlation. Combining with the results of former work, it follows that the probability of two brighter galaxies being close to each other is larger than that of fainter galaxies.
During 2016 February, CSIRO Astronomy and Space Science and the Max-Planck-Institute for Radio Astronomy installed, commissioned, and carried out science observations with a phased array feed receiver system on the 64-m diameter Parkes radio telescope. Here, we demonstrate that the phased array feed can be used for pulsar observations and we highlight some unique capabilities. We demonstrate that the pulse profiles obtained using the phased array feed can be calibrated and that multiple pulsars can be simultaneously observed. Significantly, we find that an intrinsic polarisation leakage of −31 dB can be achieved with a phased array feed beam offset from the centre of the field of view. We discuss the possibilities for using a phased array feed for future pulsar observations and for searching for fast radio bursts with the Parkes and Effelsberg telescopes.
Tuberculosis (TB) affects people globally and is being reconsidered as a serious public health problem in China. Reliable forecasting is useful for the prevention and control of TB. This study proposes a hybrid model combining autoregressive integrated moving average (ARIMA) with a nonlinear autoregressive (NAR) neural network for forecasting the incidence of TB from January 2007 to March 2016. Prediction performance was compared between the hybrid model and the ARIMA model. The best-fit hybrid model was combined with an ARIMA (3,1,0) × (0,1,1)12 and NAR neural network with four delays and 12 neurons in the hidden layer. The ARIMA-NAR hybrid model, which exhibited lower mean square error, mean absolute error, and mean absolute percentage error of 0·2209, 0·1373, and 0·0406, respectively, in the modelling performance, could produce more accurate forecasting of TB incidence compared to the ARIMA model. This study shows that developing and applying the ARIMA-NAR hybrid model is an effective method to fit the linear and nonlinear patterns of time-series data, and this model could be helpful in the prevention and control of TB.
Flour whiteness (FW) is an important factor in assessing flour quality and determining the end product quality. It is an integrated sensory indicator reflecting flour colour and is negatively correlated with protein content. In order to dissect the genetic relationship between FW and its five related traits at the quantitative trait locus (QTL)/gene level, a recombinant inbred line population was evaluated under three environments. Quantitative trait loci for FW were analysed by unconditional and conditional QTL mapping. Four unconditional additive QTLs and 16 conditional additive QTLs were detected across the three environments. Of these QTLs, only one major additive QTL (Qfw1D1-1) was consistently identified using both unconditional and conditional QTL analysis. This QTL was independent of flour colour a* (a function of red-green with a positive a* for redness and negative for greenness) and b* (a green-blue value with positive value for yellowness and negative for blueness) and was only slightly affected by flour protein content. A minor additive QTL (Qfw4A-4) was also detected using these two QTL mapping methods, being independent of flour colour a* and b*. Five unconditional and ten conditional epistatic minor QTLs were detected, from which only one pair (Qfw3A-10/Qfw6B-6) was identified by both unconditional and conditional QTL mapping, also independent of flour colour a* and b*. The major QTL (Qfw1D1-1) identified in the current study for the first time can be used for improving wheat FW in marker-assisted breeding.
Analyses for complete samples of galaxies and clusters of galaxies showed that the two-point correlation function of galaxy-galaxy and cluster-cluster have form of power law with power indices about −1.8 (Peebles, 1980; Bahcall and Soneira, 1983). Because the completeness of a sample means that we have observed completely the objects brighter than a given apparent magnitude in certain sky region. But, we know that a complete sample will be lack of faint objects at distant region. If we attempt to avoid the influences of any non-intrinsic properties on the analysis, we have to use the samples which are complete in certain interval of absolute magnitude.
Subsamples of galaxies with different morphological types have been sorted out from Stromlo-APM redshift survey. Two-point correlation function for each subsample has been calculated. The two-point correlation functions for all subsamples show very large scale fluctuation. We show that the two-point correlation function with fluctuation could be fitted by a modified power spectrum with power excess at wave number comparable to the scale of the fluctuation.