Deep learning has demonstrated its superiority in computer vision. Landsat images have specific characteristics compared with natural images. The spectral and texture features of the same class vary along with the imaging conditions. In this paper, we extend the use of deep learning to remote sensing image classification to large geographical regions, and explore a way to make deep learning classifiers transferable for different regions. We take Jingjinji region and Henan province in China as the study areas, and choose FCN, ResNet, and PSPNet as classifiers. The models are trained by different proportions of training samples from Jingjinji region. Then we use the trained models to predict results of the study areas. Experimental results show that the overall accuracy decreases when trained by small samples, but the recognition ability on mislabeled areas increases. All methods can obtain great performance when used to Jingjinji region while they all need to be fine-tuned with new training samples from Henan province, due to the reason that images of Henan province have different spectral features from the original trained area.