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Cucina, Walmsley, Gast, Martin, and Curtin (2017) started an important dialogue about survey key driver analysis (SKDA). We believe that promoting more useful and valid ways to understand survey data is critical not only for the organizations we serve, but also for advancing the relevancy of our field. We use the terms useful and valid quite intentionally. “Useful” is driven by our practitioner side, but “valid” is driven by our science side. It is the science that often sets industrial and organizational (I-O) psychology apart from other fields. But in some ways, it also holds us back from being timely and relevant. Overall, we believe that the focal article erred too much on the science side.
Some people who take selective serotonin reuptake inhibitor (SSRI)
antidepressants report that their experience of emotions is ‘blunted’.
This phenomenon is poorly understood.
To understand patients' experiences of this phenomenon.
Qualitative study, gathering data through individual interviews, a group
interview and validation interviews; and searching patient websites for
There was strong evidence that some people taking SSRIs experience
significant emotional symptoms that they strongly attribute to their
antidepressant. These emotional symptoms can be described within six key
themes. A seventh theme represents the impact of these side-effects on
everyday life, and an eighth represents participants' reasons for
attributing these symptoms to their antidepressant. Most participants
felt able to distinguish between emotional side-effects of
antidepressants and emotional symptoms of their depression or other
Emotional side-effects of SSRIs are a robust phenomenon, prominent in
some people's thoughts about their medication, having a demonstrable
impact on their functioning and playing a role in their decision-making
about antidepressant adherence.
To determine the prevalence of central venous catheter (CVC) use among patients both within and outside the ICU setting.
A 1-day prevalence survey of CVC use among adult inpatients at six medical centers participating in the Prevention Epicenter Program of the CDC. Using a standardized form, observers at each Epicenter performed a hospital-wide survey, collecting data on CVC use.
Inpatient wards and ICUs of six large urban teaching hospitals.
At the six medical centers, 2,459 patients were surveyed; 29% had CVCs. Among the hospitals, from 43% to 80% (mean, 59.3%) of ICU patients and from 7% to 39% (mean, 23.7%) of non-ICU patients had CVCs. Despite the lower rate of CVC use on non-ICU wards, the actual number of CVCs outside the ICUs exceeded that of the ICUs. Most catheters were inserted in the subclavian (55%) or jugular (22%) site, with femoral (6%) and peripheral (15%) sites less commonly used. The jugular (33.0% vs 16.6%; P < .001) and femoral (13.8% vs 2.7%; P < .001) sites were more frequently used in ICU patients, whereas peripherally inserted (19.9% vs 5.9%; P < .001) and subclavian (60.7% vs 47.3%; P < .001) catheters were more commonly used in non-ICU patients.
Current surveillance and infection control efforts to reduce morbidity and mortality associated with bloodstream infections concentrate on the high-risk ICU patients with CVCs. Our survey demonstrated that two-thirds of identified CVCs were not in ICU patients and suggests that more efforts should be directed to patients with CVCs who are outside the ICU.
Fluorescence Resonance Energy Transfer (FRET) is a process by which a fluorophore (the donor) in the excited state transfers its energy to a neighboring fluorophore (the acceptor) non-radiatively through dipole-dipole interactions. Since the efficiency of energy transfer varies as the inverse of the sixth power of the distance separating the donor and acceptor chromophores, for FRET to occur the distance between the two molecules cannot exceed 10 to 100 angstroms (1 to l0nm). The combination of FRET and optical microscopy allows examination and quantitation of dynamic molecular interactions between cellular constituents at resolutions beyond the Abbe diffraction limit of light microscopy. Through the microscope one may detect FRET by an overall decrease in fluorescence emission of the donor with a concomitant increase in fluorescence emission of the acceptor.
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