This investigation examined the hypothesis that nutrient deficiency is related to the die-back of Terminalia ivorensis. The study was conducted on three major soil groups in natural forest and T. ivorensis plantations. Five soil chemical factors, Total nitrogen, organic carbon, effective CEC, exchangeable calcium and magnesium, were positively related to die-back. Foliar nitrogen concentrations in trees suffering from die-back were almost 50% of those of healthy trees. The concentrations of magnesium in the leaves of T. ivorensis experiencing die-back were also low. Conversely, high concentrations of foliar calcium were associated with trees under stress. A highly significant relationship was observed between die-back ranks and leaf size.