The purpose of this study is to determine the navigation efficiency for transiting from various ports in Asia and Rotterdam in Europe via the Northern Sea Route. Navigation efficiency was derived from fuel consumption ratios. Preliminary research results showed that fuel consumption and the amount of carbon dioxide emissions was reduced by transiting from various ports through the European Sea Route, and the navigation efficiencies of the various ports ranked in the following descending order: Yokohama - Busan - Shanghai - Kaohsiung - Hong Kong - Singapore. The higher the ratio was, the lower the navigation efficiency of using the Northern Sea Route, i.e. more fuel was consumed and travel costs were higher. In contrast, the lower the ratio was, the higher the navigation efficiency, i.e. less fuel was consumed and travel costs were lower. Recommendations were discussed in the study.