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Although there has been widespread attention to the apparent rise of a transnational society of cross-border non-state actors alongside the international society of states, transnational society and international society have traditionally been treated as distinctive domains with different institutions. This article, by contrast, aims to transform theorization of world order through its investigation of how actors in transnational society have developed institutions that mirror in notable respects some of the primary institutions of the international society of states such as through serving constitutive and regulative functions. In addition to delineating these institutions of transnational society, the article interrogates the interdependence of these institutions of transnational society and those of international society, as well as their differences and repercussions for world order. The analysis considers how, in conjunction with the contribution of institutions of international society to international order, institutions of transnational society contribute to transnational order. By exploring not only the tensions between but also the complementarities of transnational and interstate institutions, the article both provides a reinterpretation of contemporary world order and helps reveal the potential for its more harmonious operation.
Geosequestration involves the deep geological storage of carbon dioxide from major industrial sources, providing a potential solution for reducing the rate of increase of atmospheric concentrations of carbon dioxide and mitigating climate change. This volume provides an overview of the major geophysical techniques and analysis methods for monitoring the movement and predictability of carbon dioxide plumes underground. Comprising chapters from eminent researchers, the book is illustrated with practical examples and case studies of active projects and government initiatives, and discusses their successes and remaining challenges. A key case study from Norway demonstrates how governments and other stake-holders could estimate storage capacity and design storage projects that meet the requirements of regulatory authorities. Presenting reasons for embracing geosequestration, technical best practice for carbon management, and outlooks for the future, this volume provides a key reference for academic researchers, industry practitioners and graduate students looking to gain insight into subsurface carbon management.
We sought to define the prevalence of echocardiographic abnormalities in long-term survivors of paediatric hematopoietic stem cell transplantation and determine the utility of screening in asymptomatic patients. We analysed echocardiograms performed on survivors who underwent hematopoietic stem cell transplantation from 1982 to 2006. A total of 389 patients were alive in 2017, with 114 having an echocardiogram obtained ⩾5 years post-infusion. A total of 95 patients had echocardiogram performed for routine surveillance. The mean time post-hematopoietic stem cell transplantation was 13 years. Of 95 patients, 77 (82.1%) had ejection fraction measured, and 10/77 (13.0%) had ejection fraction z-scores ⩽−2.0, which is abnormally low. Those patients with abnormal ejection fraction were significantly more likely to have been exposed to anthracyclines or total body irradiation. Among individuals who received neither anthracyclines nor total body irradiation, only 1/31 (3.2%) was found to have an abnormal ejection fraction of 51.4%, z-score −2.73. In the cohort of 77 patients, the negative predictive value of having a normal ejection fraction given no exposure to total body irradiation or anthracyclines was 96.7% at 95% confidence interval (83.3–99.8%). Systolic dysfunction is relatively common in long-term survivors of paediatric hematopoietic stem cell transplantation who have received anthracyclines or total body irradiation. Survivors who are asymptomatic and did not receive radiation or anthracyclines likely do not require surveillance echocardiograms, unless otherwise indicated.