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This study aimed to determine the age at which various ethnic groups present with thyroid cancer.
Retrospective, observational study based at three district general hospitals in the West Midlands, serving a widely diverse ethnic population. We assessed all patients undergoing an operative or core biopsy procedure for a thyroid nodule from 1 January 1998 to 31 December 2009. Only patients diagnosed with thyroid cancer were included. Variables examined included the patient's ethnic origin, sex and age at presentation.
We identified 263 patients diagnosed with thyroid cancer. Papillary carcinoma predominated. Ethnicity was categorised as Caucasian, Asian, black or other. Thyroid cancer was predominantly seen in women, in all ethnic groups. The mean age of thyroid cancer presentation was 50 years in Asians and 56 years in Caucasians, for both sexes combined. The mean presentation age of Asian women was significantly younger (46 years) than that of Caucasian women (56 years) (p = 0.01).
In this population, Asian women presented with thyroid cancer at a significantly younger mean age than Caucasian women.
We present the first report in the all English literature of a case of laryngeal squamous cell carcinoma metastasis to the orbit.
Case report of orbital metastasis from laryngeal carcinoma; clinical, radiological and pathological findings are discussed.
A 75-year-old man presented to the ENT department with a five-week history of left orbital pain, swelling and reduced vision. Past medical history included laryngectomy, bilateral neck dissection and post-operative radiotherapy for T4 N2c M0 squamous cell carcinoma of the supraglottis, 10 months earlier. Imaging showed an orbital mass extending along the roof and lateral aspect of the orbit into the optic canal and superior orbital fissure, and further posteriorly into the left cavernous sinus with meningeal enhancement in the left anterior cranial fossa. Histopathological analysis after biopsy showed the mass to be consistent with metastatic poorly differentiated squamous cell carcinoma.
After searching the all English literature, we report what is, to our best knowledge, the first case of laryngeal carcinoma metastasis to the orbit. Despite its rarity and poor prognosis, such a metastasis should be considered as part of the differential diagnosis of an orbital mass, as timely recognition can improve the patient's quality of life.
We present the first reported case of primary carcinoid tumour of the nasal septum.
Case report of our experience of a carcinoid tumour of the nasal septum. We discuss our clinical, radiological and pathological findings.
An 83-year-old woman presented with a history of left-sided nasal blockage. Clinical examination showed a unilateral, left-sided nasal polyp. Further imaging and histological analysis confirmed this to be a carcinoid tumour. Carcinoid tumours outside the gastrointestinal tract are rare. There have been reports of carcinoid tumours in the head and neck region, but no published cases occurring in the nasal septum. Our management involved wide surgical resection with regular follow up to monitor for recurrence and for the development of carcinoid syndrome. Four years from initial presentation, the patient remained free of the primary tumour and had displayed no signs or symptoms suggestive of carcinoid syndrome.
To the authors' best knowledge, and after searching the world literature, the presented case represents the first report of primary carcinoid tumour of the nasal septum. Despite its rarity, this tumour should be considered as part of the differential diagnosis, as timely recognition and intervention are critical for successful treatment.
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