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Findings for the roles of dairy products, Ca and vitamin D on ovarian cancer risk remain controversial. We aimed to assess these associations by using an updated meta-analysis. Five electronic databases (e.g. PubMed and Embase) were searched from inception to 24 December 2019. Pooled relative risks (RR) with 95 % CI were calculated. A total of twenty-nine case–control or cohort studies were included. For comparisons of the highest v. lowest intakes, higher whole milk intake was associated with increased ovarian cancer risk (RR 1·35; 95 % CI 1·15, 1·59), whereas decreased risks were observed for higher intakes of low-fat milk (RR 0·84; 95 % CI 0·73, 0·96), dietary Ca (RR 0·71; 95 % CI 0·60, 0·84) and dietary vitamin D (RR 0·80; 95 % CI 0·67, 0·95). Additionally, for every 100 g/d increment, increased ovarian cancer risks were found for total dairy products (RR 1·03; 95 % CI 1·01, 1·04) and for whole milk (RR 1·07; 95 % CI 1·03, 1·11); however, decreased risks were found for 100 g/d increased intakes of low-fat milk (RR 0·95; 95 % CI 0·91, 0·99), cheese (RR 0·87; 95 % CI 0·76, 0·98), dietary Ca (RR 0·96; 95 % CI 0·95, 0·98), total Ca (RR 0·98; 95 % CI 0·97, 0·99), dietary vitamin D (RR 0·92; 95 % CI 0·87, 0·97) and increased levels of circulating vitamin D (RR 0·84; 95 % CI 0·72, 0·97). These results show that whole milk intake might contribute to a higher ovarian cancer risk, whereas low-fat milk, dietary Ca and dietary vitamin D might reduce the risk.
Litter size has a great impact on the profit of swine producers. Uterine development is an important determinant of reproduction efficiency and could hence affect litter size. Chinese Erhualian pig is one of the most prolific breeds in the world, even though large phenotypic variation in litter size was observed within Erhualian sows. To dissect the genetic basis of the phenotypic variation, we herein conducted genome-wide association studies for total number born and number born alive (NBA) of Erhualian sows. In total, one significant single nucleotide polymorphism (SNP) (P<1.78e−06) and 11 suggestive SNPs (P<3.57e−05) were identified on 10 chromosomes, confirming seven previously reported quantitative trait loci (QTL) and uncovering six QTL for litter size or uterus length. One locus on Sus scrofa chromosome (SSC) 13 (79.28 to 90.43 Mb) harbored a cluster of suggestive SNPs associated with multiparous NBA. The SNP (rs81447100) within this region was confirmed to be significantly (P<0.05) associated with litter size in Erhualian (n=313), Sutai (n=173) and Yorkshire (n=488) populations. Retinol binding protein 2 and retinol binding protein 1 functionally related to the development of uterus were located in a region of 2 Mb around rs81447100. Moreover, four genes related to embryo implantation and development were also detected around other significant SNPs. Taken together, our findings provide a potential marker (rs81447100) for the genetic improvement of litter size not only in Chinese Erhualian pigs but also in European commercial pig breeds like Yorkshire, and would facilitate the final identification of causative variant(s) underlying the effect of SSC13 QTL on litter size.
On 27 December 2012 it was announced officially that the Chinese Navigation Satellite System BeiDou (BDS) was able to provide operational services over the Asia-Pacific region. The quality of BDS observations was confirmed as comparable with those of GPS, and relative positioning in static and kinematic modes were also demonstrated to be very promising. As Precise Point Positioning (PPP) technology is widely recognized as a method of precise positioning service, especially in real-time, in this contribution we concentrate on the PPP performance using BDS data only. BDS PPP in static, kinematic and simulated real-time kinematic mode is carried out for a regional network with six stations equipped with GPS- and BDS-capable receivers, using precise satellite orbits and clocks estimated from a global BDS tracking network. To validate the derived positions and trajectories, they are compared to the daily PPP solution using GPS data. The assessment confirms that the performance of BDS PPP is very comparable with GPS in terms of both convergence time and accuracy.
Polyaniline nanofibers (PANI-NFs)/graphite oxide (GO) nanocomposites with excellent interfacial interaction and elongated fiber structures were synthesized via a facile interfacial polymerization method. This method efficiently exfoliated the expanded layer structure of GO into individual sheet and thus significantly enhanced the specific surface area. The reduced diameter of PANI-NFs in PANI-NF/GO than that of pure PANI-NFs could shorten the diffusion distance and enhance the electro-active sites. The PANI-NFs/GO hybrid materials showed orders of magnitude enhancement in capacitance and better cycling stability than that of individual GO and PANI-NF components.
Polypropylene(PP)/Fe2O3 nanocomposites are fabricated using an in-situ method to uniformly disperse the magnetic nanoparticles (NPs) in polymer matrix. Maleic anhydride functionalized PP (f-PP) with different molecular weight is used as surfactant to stabilize the in-situ produced nanoparticles. The thermal behavior of PP and its nanocomposites with the incorporation of small amount f-PP is studied with thermal gravimetric analysis (TGA). The results show that the onset degradation temperature is increased by ~117 oC with the addition of NPs. Both melt rheology and transmission electron microscopy are used to investigate the NPs dispersion. Strong saturated magnetization (Ms) is observed after introducing f-PP to the nanocomposites through protecting the as-formed NPs from oxidation.
The characteristics of Si+ implanted into SI GaAs and its annealing behavior have been studied by x-ray double-crystal diffraction method. Results show that there is much information on strain contained in the rocking curves. When implanting at low doses, most of the implanted Si+ is in interstitial positions in the GaAs, and this produces tensile strain. After annealing, most of the implanted Si+ can be activated and the strain can be relieved. But when implanting at large doses, the strain can not be completely relieved even after annealing at high temperature
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