The effects of four different neem formulations (Neemros®, Neemroc EC®, Neemroc Combi and Saroneem) and a combination of Neemros® with a synthetic acaricide (Mitac®) on the twospotted spider mite (Tetranychus urticae Koch) were compared with Mitac® on tomato (Lycopersicon esculentum Mill.) leaf discs in the laboratory, The following LC50 were determined: Neemroc EC® 12.9 ml/1, Saroneem 5.8 ml/1, Neemroc Combi 1.0 ml/1 and Mitac® + Neemros® 1 ml/1 + 17.6 g/1. No LC50 was determined for Neemros® since the highest mortality observed was 11.4 %. The combination of Mitac® and Neemros® resulted in the highest mortality after 24 hours (83.3 %), followed by Neemroc EC® (78.3 %), Saroneem (53.4 %), Mitac® (50.8 %), Neemroc Combi (38.9 %), the control (4.5 %) and Neemros® (0.0 %). All neem formulations also caused repellence and oviposition deterrence in T. urticae.