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20 results

Early Pregnancy
  • Early Pregnancy
  • 2nd edition
  • Edited by Roy G. Farquharson, Mary D. Stephenson
  • Published online: 16 February 2017
  • Print publication: 02 February 2017
  • View description
    Updated in light of recent research findings on fertilization, implantation and early pregnancy, this new edition combines the expertise of a wide range of internationally renowned authors to produce an authoritative, multidisciplinary approach to the management of first-trimester complications. Several international guidelines and consensus statements have been released since publication of the first edition and this has stimulated new focussed research questions that are addressed. The book's key recommendations provide clinicians with the tools to improve the patient's experience of the management of first-trimester complications. By combining essential elements of scientific research and clinical care, Early Pregnancy continues to set a benchmark for evidence-based management and will be essential reading for obstetricians, gynaecologists, neonatologists, ultrasonographers, and nurses seeking an understanding of the reproductive science of early pregnancy.
  • The Blairgowrie magnetic anomaly and its interpretation using simplex optimisation
  • Colin G. Farquharson, Roy Thompson
  • Journal: Earth and Environmental Science Transactions of The Royal Society of Edinburgh / Volume 83 / Issue 3 / 1992
  • Published online by Cambridge University Press: 03 November 2011, pp. 509-518
  • Print publication: 1992
  • View abstract

    The large magnetic anomaly which runs along the Highland Boundary Fault of Scotland immediately to the NW of Blairgowrie has been studied by both a ground-based magnetic survey and a palaeomagnetic investigation. A newly developed optimisation program, making use of a simplex algorithm, was used to model the long wavelength component of this effectively two-dimensional anomaly. The consequent model consists of a vertical, rectangular body, 3 km wide and 13 km deep, whose top surface is 2 km below ground level, with a magnetisation directed vertically downwards. The composition of this body is most likely to be that of an ultra-basic, metamorphic complex which has been brought up to its present position between two of the many near-vertical faults in the area. The medium wavelength structure of the anomaly was modelled using the common technique of trial and error, and can be interpreted in terms of a pair of Devonian andesitic lavas and a small extension of the main ultrabasic block. Subsequent palaeomagnetic remanence measurements confirmed that the magnetisation of the two lavas recorded a Devonian polarity reversal. The magnetisation of the ultrabasics is directed vertically downwards, exactly as deduced from the earlier modelling work.

  • Preface
  • Geeta Kumar, Bidyut Kumar
  • Book: Early Pregnancy Issues for the MRCOG and Beyond
  • Published online: 05 July 2014
  • Print publication: 01 November 2011, pp xi-xii
  • View extract

    Summary

    The emergence of early pregnancy units into clinical practice demands educational support and the development of clear guidelines. For the inquisitive trainee, the array of information portals, both paper and electronic, can be bewildering leading to initial confusion about where to start.

    This book provides a useful vade mecum that allows a ready and accurate reference source as well as encouraging more complex reading and critical analysis for those that aspire to improved practice. This compendium represents an excellent primer while providing a solid foundation from where to start.

    It makes another useful addition to a burgeoning series.

  • Chapter 7 - Investigation of recurrent miscarriage
  • Edited by Roy G. Farquharson, University of Liverpool, Mary D. Stephenson, University of Chicago
  • Book: Early Pregnancy
  • Published online: 05 October 2010
  • Print publication: 09 September 2010, pp 59-66
  • View abstract

    Summary

    In recent years ultrasound diagnosis and improved understanding of problems related to early pregnancy have led to the introduction of medical and expectant management of miscarriage and selected cases of ectopic pregnancy. The commonest early pregnancy complication of spontaneous miscarriage occurs in approximately 15-20% of all pregnancies, as recorded by hospital episode statistics. The embryonic period occupies the first 8 postfertilization weeks, during which organogenesis takes place. Gynecologists and ultrasonographers acknowledge the embryonic period by speaking about fetal heart action and fetal activity before the end of organogenesis. Between 1% and 2% of fertile women will experience recurring miscarriage (RM). Recent papers testify to the high rate of abnormal chromosome type when pregnancy loss has occurred. By actuarial analysis, the success rate for the next pregnancy can be reasonably predicted based on maternal age and number of losses. High-resolution transvaginal ultrasound provides surveillance and reassurance for the majority of women.
Early Pregnancy
  • Early Pregnancy
  • Edited by Roy G. Farquharson, Mary D. Stephenson
  • Published online: 05 October 2010
  • Print publication: 09 September 2010
  • View description
    Problems in early pregnancy are among the most common conditions in gynaecology and obstetrics, and in recent years have become an increasingly studied and important field of reproductive medicine. Early Pregnancy is the first book to embrace a multidisciplinary approach to this rapidly growing field. It combines the expertise of a wide range of internationally renowned authors to produce an authoritative reference on the subject, aiming to improve patient care in early pregnancy by making key recommendations for clinicians. The chapters cover a wide range of core subjects as well as addressing the latest developments by translating research into clinical practice. By bringing together essential elements of scientific research and clinical care Early Pregnancy sets a new benchmark for evidence-based patient care and will be essential reading for all clinicians, nurses, trainees and scientific researchers with an interest in early pregnancy.
  • Chapter 26 - Late pregnancy loss
  • Edited by Roy G. Farquharson, University of Liverpool, Mary D. Stephenson, University of Chicago
  • Book: Early Pregnancy
  • Published online: 05 October 2010
  • Print publication: 09 September 2010, pp 277-286
  • View abstract

    Summary

    This chapter describes the principal putative causes of implantation failure and reviews therapeutic strategies. Recurrent implantation failure is a significant and distressing clinical problem. Adjuvant medical therapies to those required for ovarian hyperstimulation are frequently applied for improving embryo implantation and particularly when the clinician is faced with recurrent implantation failure. The appropriate management of the medically complicated patient presenting for in-vitro fertilization (IVF) can be complex and often requires an interdisciplinary approach. Standard ovarian hyperstimulation and the resultant supraphysiological estradiol levels have been shown to impact negatively on endometrial receptivity and embryo quality. Studies of mild ovarian stimulation regimens have shown encouraging results. Although fewer embryos are obtained, an increased percentage of euploid embryos per number of oocytes retrieved have been reported. Significant improvements in clinical pregnancy rates can be achieved by giving due attention to embryo transfer technique.