A two-year project of survey, surface collection, and excavation on the hill of Cerro Danush within the site of Dainzú-Macuilxóchitl in Oaxaca, Mexico, was focused on identifying and characterizing the Late Classic (A.D. 600–850/900) and Early Postclassic (A.D. 850/900–1300) components of the site, which coincide with the political fragmentation and reorganization of complex society within the Valley of Oaxaca. The transition in sociopolitical organization from the Classic to Postclassic has been the subject of several research projects, but few, if any, have clearly identified an Early Postclassic settlement. A radiocarbon analysis of charcoal samples collected during the excavation of a residential complex on Cerro Danush reveals its most recent period of occupation to be between A.D. 1000 and 1300, placing it firmly within the Early Postclassic. The excavation data are contextualized with data from the surface collection, illuminating patterns of Late Classic political fragmentation and Early Postclassic household resilience. Since Dainzú-Macuilxóchitl emerged in the Late Postclassic (A.D. 1300–1521) as a powerful city-state, exploring its Early Postclassic component contributes to the study of how societies reorganize on a local level after the collapse of centralized authority, such as the Classic period Monte Albán state.