To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
The renowned Gallic poet Pacatus Drepanius journeyed to Rome in the summer of AD 389 to deliver a speech to the Emperor Theodosius; both men stood for the first time before the Roman Senators. It was a moment of high political charge. The Latin speech survives and is here presented both in the original and with facing English translation; the introduction and commentary capture the groundbreaking character of the work and set it in its historical, rhetorical and literary contexts.
Transient Ischaemic Attack (TIA) is a neurologic event with symptom resolution within 24 hours. Early specialist assessment of TIA reduces risk of stroke and death. National United Kingdom (UK) guidelines recommend patients with TIA are seen in specialist clinics within 24 hours (high risk) or seven days (low risk).
We aimed to develop a complex intervention for patients with low risk TIA presenting to the emergency ambulance service. The intervention is being tested in the TIER feasibility trial, in line with Medical Research Council (MRC) guidance on staged development and evaluation of complex interventions.
We conducted three interrelated activities to produce the TIER intervention:
•Survey of UK Ambulance Services (n = 13) to gather information about TIA pathways already in use
•Scoping review of literature describing prehospital care of patients with TIA
•Synthesis of data and definition of intervention by specialist panel of: paramedics; Emergency Department (ED) and stroke consultants; service users; ambulance service managers.
The panel used results to define the TIER intervention, to include:
1.Protocol for paramedics to assess patients presenting with TIA and identify and refer low risk patients for prompt (< 7day) specialist review at TIA clinic
2.Patient Group Directive and information pack to allow paramedic administration of aspirin to patients left at home with referral to TIA clinic
3.Referral process via ambulance control room
4.Training package for paramedics
5.Agreement with TIA clinic service provider including rapid review of referred patients
We followed MRC guidance to develop a clinical intervention for assessment and referral of low risk TIA patients attended by emergency ambulance paramedic. We are testing feasibility of implementing and evaluating this intervention in the TIER feasibility trial which may lead to fully powered multicentre randomized controlled trial (RCT) if predefined progression criteria are met.
Pliny's intention that the oratio (i.e. the written version, Ep. 1.20.9) of his Panegyricus be available to posterity was explicit (Ep. 3.13, 3.18). So if his self-important aspiration that the speech prove directly instructive to future emperors (Ep. 3.18.2–3; Pan. 4.1) was not to be realized, it was not for lack of effort on his behalf, since his conscious attempt to revise and expand the original version and to secure the speech's survival through distribution seems to have been an ambitious and original project. This process of revision and publication was in keeping not only with Pliny's general practice in publishing his oratory, but also perhaps with his long-term commitment to publish his letters. As his own literary agent for his speeches and letters, Pliny was bold and innovative, but if he would have been pleased with the reception of his Panegyricus in later antiquity, it was perhaps not what he would have imagined.
Forty-three years after Pliny's suffect consulship, Fronto was to take similar office, in July and August. In a letter to Marcus Aurelius in early July 143 ce, prompted by a question from the Caesar, Fronto explained that he was postponing delivery of his gratiarum actio to Augustus Antoninus Pius for the consulship until 13 August.