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The effect of grain boundary (GB) misorientation on hot tearing susceptibility of directionally solidified (DS) nickel-based superalloys was explored. We found that the castability of second generation nickel-based superalloy CMSX-4 is inferior to DS superalloy IN792, an alloy well known for bad castability. The castability of CMSX-4 is somewhat improved at a higher solidification rate. The hot tearing tendency increases with increasing GB misorientation angle. As feeding tendency becomes greater with increasing misorientation, this points to the importance of GB cohesion for solidification cracking in the alloy. Microstructure investigation reveals that hot tearing is associated with formation of continuous gamma and gamma prime eutectic films at the GB in CMSX-4. We assume that the gamma and gamma prime eutectic, which reflects the remaining liquid at the end of solidification, prevents the impinging dendrite arms from touching and in this way decreases cohesion.