Borsboom et al. discuss the implications of network structures for neurobiology-based reductionism, but inherent in the network approach is that dimensional models of psychopathology are untenable as well. Insofar as mental disorders are complex dynamic constellations of symptoms, the “trait reductionism” of dimensional psychopathology frameworks suffers from the same limitations as neurobiological reductionism.

Although the network model represents a promising new approach to conceptualizing comorbidity in psychiatric diagnosis, the model applies most directly to Axis I symptom disorders; the degree to which the model generalizes to Axis II disorders remains open to question. This commentary addresses that issue, discussing opportunities and challenges in applying the network model to DSM-diagnosed personality pathology.

Contrary to Perruchet & Vinter's self-organizing consciousness (SOC) model, subliminal mere exposure (SME) research indicates that stimuli perceived without awareness produce robust effects. Moreover, SME effects are significantly stronger than mere exposure effects produced by clearly recognized stimuli. The SOC model must be revised to accommodate findings from studies that use affect-based outcome measures.

A comprehensive theory of implicit and explicit knowledge must explain phenomenal knowledge (e.g., knowledge regarding one's affective and motivational states), as well as propositional (i.e., “fact”-based) knowledge. Findings from several research areas (i.e., the subliminal mere exposure effect, artificial grammar learning, implicit and self-attributed dependency needs) are used to illustrate the importance of both phenomenal and propositional knowledge for a unified theory of implicit and explicit mental states.

Antimicrobial resistance results in increased morbidity, mortality, and costs of health care. Prevention of the emergence of resistance and the dissemination of resistant microorganisms will reduce these adverse effects and their attendant costs. Appropriate antimicrobial stewardship that includes optimal selection, dose, and duration of treatment, as well as control of antibiotic use, will prevent or slow the emergence of resistance among microorganisms. A comprehensively applied infection control program will interdict the dissemination of resistant strains

Mele's analysis of self-deception is persuasive but it might also be useful to consider the varieties of self-deception that occur in real-world settings. Instances of self-deception can be classified along three dimensions: implicit versus explicit, motivated versus process-based, and public versus private. All three types of self-deception have implications for the scientific research enterprise.