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We developed a tilt sensor for studying ice deformation and installed our tilt sensor systems in two boreholes drilled close to the shear margin of Jarvis Glacier, Alaska to obtain kinematic measurements of streaming ice. We used the collected tilt data to calculate borehole deformation by tracking the orientation of the sensors over time. The sensors' tilts generally trended down-glacier, with an element of cross-glacier flow in the borehole closer to the shear margin. We also evaluated our results against flow dynamic parameters derived from Glen's exponential flow law and explored the parameter space of the stress exponent n and enhancement factor E. Comparison with values from ice deformation experiments shows that the ice on Jarvis is characterized by higher n values than that is expected in regions of low stress, particularly at the shear margin (~3.4). The higher n values could be attributed to the observed high total strains coupled with potential dynamic recrystallization, causing anisotropic development and consequently sped up ice flow. Jarvis' n values place the creep regime of the ice between basal slip and dislocation creep. Tuning E towards a theoretical upper limit of 10 for anisotropic ice with single-maximum fabric reduces the n values by 0.2.
Chapter 1 argues that the Clerk’s performance, like Chaucer’s earlier House of Fame, presents an array of different and even contradictory conceptions of literary value in order to give Chaucer’s fiction the distinctive meta-value of standing above any one commitment to literary value, playfully and provocatively assessing competing options, and thereby positioning the implied author as a master of the literary game. For the House of Fame this sort of meta-value serves the purpose of imagining the social identity of customs controller as a legitimate and distinctive locus for poetic composition. In the Clerk’s performance Chaucer imagines the university student as a normative masculine occupation for which meta-axiology is an end in itself, and thereby gives his earlier position a more authoritative and traditional institutional home. To pursue this argument, the chapter considers the House of Fame; select features of the Clerk’s prologue, tale, and epilogue, for the tale focusing on specific wording in light of its Petrarchan source; and the Clerk’s portrait, placing it against the backdrop of what we know about the normative function of the university in Chaucer’s day.
Chapter 2 argues that the positioning of the Merchant’s performance as an answer to the Clerk’s stages a stern critique of the naïve escapism of the poet-student occupation as the Clerk’s performance imagines it. In this view, the Clerk’s meta-value is an attempt to avoid confronting the true nature of value in the sublunary realm: the material desires of flesh-and-blood individuals. According to the Merchant’s performance, all discourse is a self-interested instrument of these desires. Yet the chapter also argues that this grim position is not one voiced by a bitter man far removed from Chaucer, but rather that the tale is told with the very narratorial wit and playfulness most characteristic of Chaucer’s fiction, whether in his first-person voice or otherwise. For this reason, the Merchant’s dialectical negation of the Clerk’s notion of literary value represents at once Chaucer’s skepticism about the value of his own craft and his reveling in his mastery over it. To pursue this argument, the chapter performs a close reading of the Merchant’s Prologue, examines key moments in the Merchant’s Tale, and considers the Merchant’s portrait in its historical context.
Chapter 3 argues that the division of the four-tale sequence into two fragments has obscured the pivotal function of the Squire’s performance, and especially of the linking passage that accomplishes the positioning of this performance as the dialectical answer to the Merchant’s response to the Clerk. Negating the Merchant’s negation of the Clerk, the Squire’s performance reinstates literary value as the power of the distinctive discourse of romance fiction: the power to provide a restorative vision of a world governed by exactly the kind of ideals that the Merchant’s view understands as mere smokescreens for material desire. Moreover, by associating this kind of literary value with the normative sociocultural practice of a young aristocrat, the Squire’s performance understands literary discourse as also possessing the concrete value of the cultural capital that helps distinguish the elite from the common. The chapter concludes that the Squire’s response to the Merchant nonetheless collapses, not for dramatic reasons (as one trend in criticism has held), but because of a contradiction at the heart of its view of literary value that Chaucer could not overcome.
After presenting book’s justification, the introduction articulates its central argument: that the four-tale sequence of Clerk, Merchant, Squire, and Franklin enacts a dynamically unfolding, conflicted meditation on how literary value may be construed in a way that justifies the time, energy, and expense devoted to the writing of fiction - a justification made in respect to other activities pertaining to other values, especially to economic value in the sense of making a living. The introduction then considers the metacritical stakes and implications of this argument along the methodological dimension of the bearing of manuscript evidence on the principles of Chaucer interpretation and the conceptual dimension of the problem literary value. The former consideration reviews the manuscript basis for the book’s claim about the four-tale sequence; the latter consideration indicates theoretical debts (to, e.g., Bruno Latour and Georg Simmel) and introduces several key terms used throughout the book (the most important: literary axiology, axiological person, and axiological logic), explaining the relation of these terms to more traditional ones of Chaucer criticism.
Chapter 4 argues that the Franklin’s performance serves as the dialectical synthesis of the views on value of the preceding performances, encompassing the wondrous renewal of the Squire, the amoral instrumentalism of the Merchant, and the meta-value of the Clerk. In this way, the Franklin’s performance presents a sober, disenchanted, but nonetheless ultimately affirmative meditation on the creative power of fiction - one that recognizes fiction’s instrumental value but insists that a paradoxically knowing mystification of this instrumentality can be the basis for a practicable ethics for living in a fallen world. To pursue this argument, the chapter performs a close reading of the Squire-Franklin link (taking into account the bearing of manuscript evidence), examines key aspects of the tale’s prologue and narrative, and considers the Franklin’s portrait in respect to the social status of franklins in Chaucer’s day. It concludes that the performance formulates a commitment to literary value that not only transcends the vulnerabilities of the preceding tales, but is also precisely the literary value that someone socially situated like Chaucer is best positioned to create.
Literary authors, especially those with other occupations, must come to grips with the question of why they should write at all, when the world urges them to devote their time and energy to other pursuits. They must reach, at the very least, a provisional conclusion regarding the relation between the uncertain value of their literary efforts and the more immediate values of their non-authorial social identities. Geoffrey Chaucer, with his several middle-strata identities, grappled with this question in a remarkably searching, complex manner. In this book, Robert J. Meyer-Lee examines the multiform, dynamic meditation on the relation between literary value and social identity that Chaucer stitched into the heart of The Canterbury Tales. He traces the unfolding of this meditation through what he shows to be the tightly linked performances of Clerk, Merchant, Franklin and Squire, offering the first full-scale reading of this sequence.
Catheter-associated urinary tract infections in 592 hospitals immediately declined after federal value-based incentive program implementation, but this was fully attributable to a concurrent surveillance case definition revision. Post revision, more hospitals had favorable standardized infection ratios, likely leading to artificial inflation of their performance scores unrelated to changes in patient safety.
However well-regarded Chaucer’s works were during his lifetime, it was his immediate successors who fashioned him into the ‘father of English poetry’ they then bequeathed to the subsequent English literary tradition. In particular, the poets Thomas Hoccleve and John Lydgate not only represented Chaucer in this manner in their own, widely disseminated works, they were also instrumental in the broad dissemination of Chaucer’s works. Importantly, these activities were motivated not just by admiration but also by a politico-literary context in which Hoccleve and Lydgate, unlike Chaucer, were asked to produce works that spoke both for a prince and to a prince. Their invention of Chaucer’s literary authority cannot then be separated from their intervention into politics, and this conflation they also bequeathed to the English literary tradition, where it remained plainly visible in the works of their own successors, and where it persists, more obscurely, to the present.
We investigated whether neurobehavioral markers of risk for emotion dysregulation were evident among newborns, as well as whether the identified markers were associated with prenatal exposure to maternal emotion dysregulation. Pregnant women (N = 162) reported on their emotion dysregulation prior to a laboratory assessment. The women were then invited to the laboratory to assess baseline respiratory sinus arrhythmia (RSA) and RSA in response to an infant cry. Newborns were assessed after birth via the NICU Network Neurobehavioral Scale. We identified two newborn neurobehavioral factors—arousal and attention—via exploratory factor analysis. Low arousal was characterized by less irritability, excitability, and motor agitation, while low attention was related to a lower threshold for auditory and visual stimulation, less sustained attention, and poorer visual tracking abilities. Pregnant women who reported higher levels of emotion dysregulation had newborns with low arousal levels and less attention. Larger decreases in maternal RSA in response to cry were also related to lower newborn arousal. We provide the first evidence that a woman's emotion dysregulation while pregnant is associated with risks for dysregulation in her newborn. Implications for intergenerational transmission of emotion dysregulation are discussed.
Agetolites is a problematic Late Ordovician genus possessing traits of both tabulate and rugose corals. The presence of numerous mural pores has often been considered to indicate a relation to tabulates, although an affinity to rugosans has also been proposed, based mainly on well-developed septa that alternate in length. To further consider the taxonomic position of Agetolites, growth characteristics of coralla representing three species from the Xiazhen Formation in South China are documented and assessed, focusing on modes of corallite increase. Three major modes of increase are recognized. By far the most common mode involves the development of an offset from a connective mural pore, without a clear relationship to a particular parent corallite. This mode of increase is usually associated with corner pores, but in one case occurs at a wall pore. The lateral mode of increase, which is relatively uncommon, is a typical feature in corallites along the boundary of intergrowths with stromatoporoids. The axial mode of increase is rare, occurring during rejuvenation of a damaged corallite or during regeneration following termination of a corallite. The mode of corallite increase that is characteristic of Agetolites, involving a connective mural pore and occurring without evidence of a particular parent, supports the interpretation that this genus is not a rugosan or a typical favositid tabulate. Mural pores are unknown in rugosans, and offsets arise from distinct parent corallites in favositids. The Ordovician genus Lichenaria, considered a representative of the most primitive stock of tabulate corals, shows the closest similarities with types of increase in Agetolites. Certain aspects of lateral and axial increase in Agetolites are comparable to features in a few more genera of Ordovician tabulates, further supporting a tabulate affinity. The phylogenetic relation of Agetolites to those and other tabulate genera, however, remains unresolved.
OBJECTIVES/SPECIFIC AIMS: I would like to make clinicians aware about prescription opioid use and glycemic control among patients with diabetes. This is a quality of care issue that increases the disease burden for two conditions opioid dependence and diabetic complications. Big data analytics can bring out this quality of care issue and help in changing clinical practice through precision medicine METHODS/STUDY POPULATION: This is a population health study of patients on prescription opioid pain medications in Erie county medical center and local out patient clinic. The electronic data from the hospital records and Outpatient were collected, merged and de identified. The database was saved in a protected environment and made accessible to researchers through a secure login. The data was queried for the number of patients with diabetes. The glycohemoglobin levels were collected and then the analysis was made RESULTS/ANTICIPATED RESULTS: It was found that only 63 of the 89 patients with DPN and 156 of the 570 patients without DPN had any measurement of HbA1c in our data. It was found that 86 out of 156 patients without DPN had suboptimal glycemic control with a glycohemoglobin level > 7% while 36 out of 63 patients with DPN had a glycohemoglobin > 6.7%. The odds of patients with DPN having poor glycemic control is 0.57 while the odds of having poor glycemic control without DPN is.55. The relative risk being 1.03. DISCUSSION/SIGNIFICANCE OF IMPACT: Our population study revealed suboptimal glycemic control among a large set of patients in Western New York with a diagnosis of diabetes mellitus and a concurrent prescription for an opioid pain medication. A significant percentage of patients in our study population with a diagnosis of DPN might benefit in terms of decreased painful symptoms of neuropathy from monitoring and attempting to improve glycemic control. Additionally, in our patient population, there were no patients with diabetic peripheral neuropathy prescribed pregabalin or duloxetine, the first-line FDA-approved medications for painful DPN, Based on our population study, the quality of care for diabetic patients with DPN who are prescribed opioid pain medications should be monitored closely. First-line, FDA approved anticonvulsants and antidepressants should be considered for the treatment of painful symptoms when necessary. Attention should be directed towards monitoring and improving glycemic control in patients without DPN receiving opioid pain medications to attempt to prevent or delay the microvascular complications of diabetes, including the onset of painful peripheral neuropathy.