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Endometrial hyperplasia can be termed as a premalignant condition of the endometrium. Women presenting with postmenopausal bleeding are at the risk of having endometrial cancer and investigations to confirm or exclude such a possibility should be performed. The standard surgical procedure for the management of endometrial cancer is hysterectomy and bilateral salpingo-oophorectomy by the method for evaluation of the peritoneal cavity. Patients with clear-cell or papillary serous tumours may receive pelvic radiotherapy and adjuvant chemotherapy to try to impact on the possibility of extrapelvic relapse. The optimum management of endometrial cancers requires close coordination between the primary healthcare team, the treatment teams at the cancer unit and cancer centre, the palliative care team and patients and their families. For endometrial cancer, the cancer unit should provide a rapid and appropriate assessment service at the local level for women with postmenopausal bleeding.
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