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As wildlife becomes more isolated in human-dominated and rapidly changing environments, species conservation requires investment in landscape connectivity. Identifying stepping stones (discrete areas of suitable habitat that facilitate the movement of dispersing individuals) can help meet connectivity goals. We report the occurrence of the snow leopard Panthera uncia in Ikh Nart Nature Reserve, Mongolia, over 250 km from the nearest known population, one of the easternmost records for the species. Ikh Nart Nature Reserve lies within a region considered highly resistant to movement but harbours high densities of argali sheep Ovis ammon and Siberian ibexes Capra sibirica, both important prey items for snow leopards. This occurrence reveals a new distribution record for the species, the capacity of the species to move across low-quality environments, the value of investment in community conservation and collaborative park management, and the role of remote protected areas such as Ikh Nart Nature Reserve as stepping stones for facilitating population expansion and broader connectivity to other potentially suitable but unoccupied areas.
Among nursing home outbreaks of coronavirus disease 2019 (COVID-19) with ≥3 breakthrough infections when the predominant severe acute respiratory coronavirus virus 2 (SARS-CoV-2) variant circulating was the SARS-CoV-2 δ (delta) variant, fully vaccinated residents were 28% less likely to be infected than were unvaccinated residents. Once infected, they had approximately half the risk for all-cause hospitalization and all-cause death compared with unvaccinated infected residents.
The Residual Lesion Score is a novel tool for assessing the achievement of surgical objectives in congenital heart surgery based on widely available clinical and echocardiographic characteristics. This article describes the methodology used to develop the Residual Lesion Score from the previously developed Technical Performance Score for five common congenital cardiac procedures using the RAND Delphi methodology.
Methods:
A panel of 11 experts from the field of paediatric and congenital cardiology and cardiac surgery, 2 co-chairs, and a consultant were assembled to review and comment on validity and feasibility of measuring the sub-components of intraoperative and discharge Residual Lesion Score for five congenital cardiac procedures. In the first email round, the panel reviewed and commented on the Residual Lesion Score and provided validity and feasibility scores for sub-components of each of the five procedures. In the second in-person round, email comments and scores were reviewed and the Residual Lesion Score revised. The modified Residual Lesion Score was scored independently by each panellist for validity and feasibility and used to develop the “final” Residual Lesion Score.
Results:
The Residual Lesion Score sub-components with a median validity score of ≥7 and median feasibility score of ≥4 that were scored without disagreement and with low absolute deviation from the median were included in the “final” Residual Lesion Score.
Conclusion:
Using the RAND Delphi methodology, we were able to develop Residual Lesion Score modules for five important congenital cardiac procedures for the Pediatric Heart Network’s Residual Lesion Score study.
While dependency analysis has a long tradition within Latin America, only recently has it emerged from the relative obscurity of certain Latin American writers to be included among the approaches used by scholars in the United States. The dependency approach was first adopted by a group of “radicals” in the United States, partially as a reaction to U.S. involvement in Vietnam, but also as part of a general attack on the capitalist system, the military-industrial complex, and U.S. imperialism. It is now evident that dependency analysis has emerged as a legitimate field of inquiry for Latin Americanists, even if some scholars refuse to acknowledge its existence. In spite of generating considerable analysis of Latin America and the inter-American system, the dependen tistas have not been subjected to the critical scrutiny they deserve, primarily because of the lack of academic respectability of the radicals and the different channels through which their publications appear. Aside from the critiques of Raul Prebisch (Flanders, 1964; Hodgson, 1966; Salera, 1971), an article by David Ray (1973), and the internal bickerings among the dependentistas themselves, systematic criticism of the dependency approach has been lacking. For this reason we felt the need to delineate the broad outlines of the dependency theory of underdevelopment; present a selective critique of the methodologies, content, and conclusions of the major writers; and identify some of the more potentially rewarding areas for subsequent research.
This article develops a conceptual framework for explaining variation in the United States’ economic statecraft in the Cold War and the present day, focusing on how US officials perceived the type of geoeconomic capability that its rivals possessed and the type of national security challenge that they posed. This framework specifies four ideal-type strategies on the part of the United States: economic containment, national economic competition, technological containment, and national technological competition. Analyses of U.S. strategy toward the Soviet Union, China, and Japan support the theory. These ideal types explain why, in the rivalry with Japan in the 1980s, the United States openly engaged in competition but did not adopt containment, relying on Voluntary Export Restraints, currency devaluation agreements, and bilateral semiconductor agreements rather than placing Japan on something historically analogous to the Commerce Department's contemporary Entity List or targeting Japan with comprehensive export controls through an institution like CoCom. These ideal types (and the theory behind them) also explain why the United States has implemented containment measures against specific Chinese companies but has not pursued a systematic “decoupling” of the US and Chinese economies.
Wet winter conditions can create animal welfare issues in feedlots if the pen surface becomes a deep, wet, penetrable substrate. Feedlot pens with a clay and gravel base (N = 30) bedded with 150 mm (W15) and 300 mm (W30) depth of woodchips were compared to a control treatment with no bedding over a 109-day feeding period, while irrigated to supplement natural rainfall. The pad substrate was measured for variables which would affect cattle comfort and value of the substrate for composting. The penetrable depth of control pens was higher than both woodchip-bedded treatments from week 2, and increased until the end of the experiment. Meanwhile these scores were steady for W30 throughout the experiment, and increased for W15 only after week 10. Moisture content of the pad was higher throughout the experiment in the control pens than in the woodchip-bedded pens. In the control pens, the force required to pull a cattle leg analogue out of the pen substrate was three times that required in woodchip-bedded treatments. The W15 treatment increased C : N in the substrate to the upper limit of suitability for composting, and in W30, C : N was too high for composting after a 109-day feeding period. Overall, providing feedlot cattle with 150 or 300 mm of woodchip bedding during a 109-day feeding period improved the condition of the pad substrate for cattle comfort by reducing penetrable depth and moisture content of the substrate surface stratum, but composting value decreased in W30 over this feeding period duration.
Benevolent intersubjectivity developed in parent–infant interactions and compassion toward friend and foe alike are non-violent interventions to group behavior in conflict. Based on a dyadic active inference framework rooted in specific parental brain mechanisms, we suggest that interventions promoting compassion and intersubjectivity can reduce stress, and that compassionate mediation may resolve conflicts.
Pangolins are some of the most overexploited but least studied mammals. The giant pangolin Smutsia gigantea is the largest of the eight pangolin species, measuring up to 180 cm in length and weighing up to 40 kg. It is a nocturnal, solitary species that occurs at low densities and little is known regarding its biology and ecology. It is distributed widely across the rainforests and forest savannah mosaics of equatorial Africa but its exact range extent is unknown. Apart from a single record in Kenya predating 1971, the eastern limit of its range was thought only to extend to central Uganda and western Tanzania. Here we present three spatially separate records confirming the presence of this species in Kenyan Afromontane forests. The three records are c. 120 km apart and c. 500 km east of the nearest confirmed giant pangolin population in Uganda. These records represent a significant range extension for the species and highlight the biodiversity and conservation importance of the Afromontane forests of western Kenya.
This chapter presents a synopsis of some of the latest developments in our understanding of pyroconvective interactions, their links to fire geometrym and their role in driving dynamic fire behavior and extreme wildfire development. We highlight the need to augment traditional quasi-steady wildfire modeling paradigms with more sophisticated approaches that combine highly-instrumented, larger-scale experimental studies with state-of-the-art computational modeling. We identify the need to take maximum advantage of technical advances in remote sensing technology to provide new ways of observing extreme fire events.
The performance benefits of deploying tidal turbines in close side-by-side proximity to exploit constructive interference effects are demonstrated experimentally using two 1.2 m diameter turbines. The turbines are arrayed side-by-side at 1/4 diameter tip-to-tip spacing, and their performance compared with that of a single rotor. Tests were completed in the 25 m diameter, 2 m deep wave and current FloWave Ocean Energy Research facility. A detailed assessment of inflow conditions at different control points is used to understand the impact that rotors, designed for high blockage conditions, have on the approach flow. After accounting for global blockage, a 10.8 % uplift in the twin-turbine-averaged power coefficient, relative to that for a single turbine, is found for the turbine design speed, at the expense of a 5.2 % increase in thrust coefficient and 3.1 % increase in tip-speed-ratio. Flowfield mapping demonstrated flow effects at array and device scale including array bypass flows and jetting between turbines. Azimuthal variation of blade root flapwise and edgewise bending moments show that the turbines interact in a beneficial manner, with additional and sustained loading peaks as the blades pass in close proximity to the neighbouring rotor. Peak performance for the twin turbines occurred at a higher tip-speed-ratio than for the single turbine, which is consistent with the twin turbines exerting a higher thrust on the flow to achieve maximum power. The twin turbine performance variation with tip-speed-ratio is found to be more gradual than for the single turbine. Using differential rotor speed control we observe that array performance is robust to small differences in neighbouring rotor operating point. Through these experiments we demonstrate that there is a substantial, achievable performance benefit from closely arraying turbines for side-by-side operation and designing them for constructive interference.
The Homa Peninsula has been known to science since 1911, and fossil specimens from the area comprise many type specimens for common African mammalian paleospecies. Here we discuss the fauna and the paleoenvironmental information from the Homa Peninsula. The Homa Peninsula is a 200 km2 area in Homa Bay County, situated on the southern margin of the Winam Gulf of Lake Victoria in Kenya (Figure 29.1). Lake Victoria is estimated to be the third largest lake in the world, with a surface area of 68,900 km2 and a maximum length of approximately 616 km. Although its catchment is extensive, it is relatively shallow compared to any other lake of similar size, with a maximum depth of 84 m. Lake Victoria is located in a depression formed by the western and eastern branches of the East African Rift System (EARS), and is at an average elevation of 1135 m a.s.l. (Database for Hydrological Time Series of Inland Waters, 2017).
Prisons are susceptible to outbreaks. Control measures focusing on isolation and cohorting negatively affect wellbeing. We present an outbreak of coronavirus disease 2019 (COVID-19) in a large male prison in Wales, UK, October 2020 to April 2021, and discuss control measures.
We gathered case-information, including demographics, staff-residence postcode, resident cell number, work areas/dates, test results, staff interview dates/notes and resident prison-transfer dates. Epidemiological curves were mapped by prison location. Control measures included isolation (exclusion from work or cell-isolation), cohorting (new admissions and work-area groups), asymptomatic testing (case-finding), removal of communal dining and movement restrictions. Facemask use and enhanced hygiene were already in place. Whole-genome sequencing (WGS) and interviews determined the genetic relationship between cases plausibility of transmission.
Of 453 cases, 53% (n = 242) were staff, most aged 25–34 years (11.5% females, 27.15% males) and symptomatic (64%). Crude attack-rate was higher in staff (29%, 95% CI 26–64%) than in residents (12%, 95% CI 9–15%).
Whole-genome sequencing can help differentiate multiple introductions from person-to-person transmission in prisons. It should be introduced alongside asymptomatic testing as soon as possible to control prison outbreaks. Timely epidemiological investigation, including data visualisation, allowed dynamic risk assessment and proportionate control measures, minimising the reduction in resident welfare.
Democratic cooperation is a particularly complex type of arrangement that requires attendant institutions to ensure that the problems inherent in collective action do not subvert the public good. It is perhaps due to this complexity that historians, political scientists, and others generally associate the birth of democracy with the emergence of so-called states and center it geographically in the “West,” where it then diffused to the rest of the world. We argue that the archaeological record of the American Southeast provides a case to examine the emergence of democratic institutions and to highlight the distinctive ways in which such long-lived institutions were—and continue to be—expressed by Native Americans. Our research at the Cold Springs site in northern Georgia, USA, provides important insight into the earliest documented council houses in the American Southeast. We present new radiocarbon dating of these structures along with dates for the associated early platform mounds that place their use as early as cal AD 500. This new dating makes the institution of the Muskogean council, whose active participants have always included both men and women, at least 1,500 years old, and therefore one of the most enduring and inclusive democratic institutions in world history.
Post-operative oral feeding difficulties in neonates and infants with CHD is common. While pre-operative oral feeding may be normal, oral feeding challenges manifest in the post-operative period without a clearly defined aetiology. The objective of this scoping review was to examine post-operative oral feeding in full-term neonates and infants with a CHD. Electronic databases query (1 January 1975–31 May 2021), hand-search of the reference lists of included studies, contact with experts, and review of relevant conferences were performed to identify quantitative studies evaluating post-operative oral feeding in full-term neonates and infants with a CHD. Associations with additional quantitative variables in these studies were also examined. Twenty-five studies met inclusion criteria. Eighty per cent were cohort studies that utilised retrospective chart review from a single institution. The primary variable of interest in all studies was oral feeding status upon discharge from neonatal hospitalisation. The most common risk factors evaluated with poor feeding at time of discharge were birth weight (36% of included studies), gestational age (44%), duration of post-operative intubation (48%), cardiac diagnosis (40%), and presence of genetic syndrome or chromosomal anomaly (36%). The most common health-related outcomes evaluated were length of hospital stay (40%) and length of ICU stay (16%). Only the health-related outcomes of length of hospital stay and length of ICU stay were consistently significantly associated with poor post-operative oral feeding across studies in this review. A clear aetiology of poor post-operative oral feeding remains unknown.
Theorems of hyperarithmetic analysis (THAs) occupy an unusual neighborhood in the realms of reverse mathematics and recursion-theoretic complexity. They lie above all the fixed (recursive) iterations of the Turing jump but below ATR
$_{0}$
(and so
$\Pi _{1}^{1}$
-CA
$_{0}$
or the hyperjump). There is a long history of proof-theoretic principles which are THAs. Until the papers reported on in this communication, there was only one mathematical example. Barnes, Goh, and Shore [1] analyze an array of ubiquity theorems in graph theory descended from Halin’s [9] work on rays in graphs. They seem to be typical applications of ACA
$_{0}$
but are actually THAs. These results answer Question 30 of Montalbán’s Open Questions in Reverse Mathematics [19] and supply several other natural principles of different and unusual levels of complexity.
This work led in [25] to a new neighborhood of the reverse mathematical zoo: almost theorems of hyperarithmetic analysis (ATHAs). When combined with ACA
$_{0}$
they are THAs but on their own are very weak. Denizens both mathematical and logical are provided. Generalizations of several conservativity classes (
$\Pi _{1}^{1}$
, r-
$\Pi _{1}^{1}$
, and Tanaka) are defined and these ATHAs as well as many other principles are shown to be conservative over RCA
$_{0}$
in all these senses and weak in other recursion-theoretic ways as well. These results answer a question raised by Hirschfeldt and reported in [19] by providing a long list of pairs of principles one of which is very weak over RCA
$_{0}$
but over ACA
$_{0}$
is equivalent to the other which may be strong (THA) or very strong going up a standard hierarchy and at the end being stronger than full second-order arithmetic.
The mental health impact of the initial years of military service is an under-researched area. This study is the first to explore mental health trajectories and associated predictors in military members across the first 3–4 years of their career to provide evidence to inform early interventions.
Methods
This prospective cohort study surveyed Australian Defence personnel (n = 5329) at four time-points across their early military career. Core outcomes were psychological distress (K10+) and posttraumatic stress symptoms [four-item PTSD Checklist (PCL-4)] with intra-individual, organizational and event-related trajectory predictors. Latent class growth analyses (LCGAs) identified subgroups within the sample that followed similar longitudinal trajectories for these outcomes, while conditional LCGAs examined the variables that influenced patterns of mental health.
Results
Three clear trajectories emerged for psychological distress: resilient (84.0%), worsening (9.6%) and recovery (6.5%). Four trajectories emerged for post-traumatic stress, including resilient (82.5%), recovery (9.6%), worsening (5.8%) and chronic subthreshold (2.3%) trajectories. Across both outcomes, prior trauma exposure alongside modifiable factors, such as maladaptive coping styles, and increased anger and sleep difficulties were associated with the worsening and chronic subthreshold trajectories, whilst members in the resilient trajectories were more likely to be male, report increased social support from family/friends and Australian Defence Force (ADF) sources, and use adaptive coping styles.
Conclusions
The emergence of symptoms of mental health problems occurs early in the military lifecycle for a significant proportion of individuals. Modifiable factors associated with wellbeing identified in this study are ideal targets for intervention, and should be embedded and consolidated throughout the military career.
Sexual violence has proven to be associated with sexually transmitted infections (STIs) in sub-Saharan Africa (SSA). We examined the association between sexual violence and self-reported STIs (SR-STIs) among women in sexual unions in 15 sub-Saharan African countries. This was a cross-sectional study involving the analysis of data from the Demographic and Health Surveys (DHS) from 15 countries in SSA. A total sample of 65,392 women in sexual unions were included in the final analysis. A multilevel binary logistic regression analysis was carried out and the results were presented using adjusted odds ratios (aOR) at 95% Confidence Interval (CI). Women who experienced sexual violence in the last 12 months were more likely to self-report STIs compared to those who did not experience sexual violence [aOR = 1.76, 95% CI = 1.59-1.94]. Compared to women in Angola, those who were in Mali, Nigeria, Sierra Leone, Uganda, and Liberia were more likely to self-report STIs while those in Burundi, Cameroon, Chad, Ethiopia, Malawi, Rwanda, South Africa, Zambia, and Zimbabwe were less likely to self-report STIs. The study has revealed variations in the country level regarding the prevalence of sexual violence and SR-STI in the last 12 months among women in sexual unions in the selected countries. This study has demostrated that sexual violence in the last 12 months is associated with SR-STIs among women in sexual unions. Moreover, factors that predict SR-STIs were observed in this study. Policymakers and agencies that matter could consider the factors identified in this study when designing policies or strengthening existing ones to tackle STIs among women in SSA. To accelerate the progress towards the achievement of Sustainable Development Goal 3, its imperative efforts and interventions must be intensified in SSA to reduce sexual violence which will go a long way to reduce SR-STIs among women.
Schizophrenia (SZ), bipolar disorder (BD) and depression (D) run in families. This susceptibility is partly due to hundreds or thousands of common genetic variants, each conferring a fractional risk. The cumulative effects of the associated variants can be summarised as a polygenic risk score (PRS). Using data from the EUropean Network of national schizophrenia networks studying Gene-Environment Interactions (EU-GEI) first episode case–control study, we aimed to test whether PRSs for three major psychiatric disorders (SZ, BD, D) and for intelligent quotient (IQ) as a neurodevelopmental proxy, can discriminate affective psychosis (AP) from schizophrenia-spectrum disorder (SSD).
Methods
Participants (842 cases, 1284 controls) from 16 European EU-GEI sites were successfully genotyped following standard quality control procedures. The sample was stratified based on genomic ancestry and analyses were done only on the subsample representing the European population (573 cases, 1005 controls). Using PRS for SZ, BD, D, and IQ built from the latest available summary statistics, we performed simple or multinomial logistic regression models adjusted for 10 principal components for the different clinical comparisons.
Results
In case–control comparisons PRS-SZ, PRS-BD and PRS-D distributed differentially across psychotic subcategories. In case–case comparisons, both PRS-SZ [odds ratio (OR) = 0.7, 95% confidence interval (CI) 0.54–0.92] and PRS-D (OR = 1.31, 95% CI 1.06–1.61) differentiated AP from SSD; and within AP categories, only PRS-SZ differentiated BD from psychotic depression (OR = 2.14, 95% CI 1.23–3.74).
Conclusions
Combining PRS for severe psychiatric disorders in prediction models for psychosis phenotypes can increase discriminative ability and improve our understanding of these phenotypes. Our results point towards the potential usefulness of PRSs in specific populations such as high-risk or early psychosis phases.