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At first sight, these two volumes represent different views of the task of interpreting material culture: the first seems to announce a post-processual paradigm, emphasising the agency of objects and the ambivalence of meanings in the area of magical practice, whereas the second makes no overt claims about materiality while based firmly on museum objects. In fact, however, the differences between them are rather smaller than first impressions suggest.
Electroconvulsive therapy (ECT) is recommended in treatment guidelines as an efficacious therapy for treatment-resistant depression. However, it has been associated with loss of autobiographical memory and short-term reduction in new learning.
To provide clinically useful guidelines to aid clinicians in informing patients regarding the cognitive side-effects of ECT and in monitoring these during a course of ECT, using complex data.
A Committee of clinical and academic experts from Australia and New Zealand met to the discuss the key issues pertaining to ECT and cognitive side-effects. Evidence regarding cognitive side-effects was reviewed, as was the limited evidence regarding how to monitor them. Both issues were supplemented by the clinical experience of the authors.
Meta-analyses suggest that new learning is impaired immediately following ECT but that group mean scores return at least to baseline by 14 days after ECT. Other cognitive functions are generally unaffected. However, the finding of a mean score that is not reduced from baseline cannot be taken to indicate that impairment, particularly of new learning, cannot occur in individuals, particularly those who are at greater risk. Therefore, monitoring is still important. Evidence suggests that ECT does cause deficits in autobiographical memory. The evidence for schedules of testing to monitor cognitive side-effects is currently limited. We therefore make practical recommendations based on clinical experience.
Despite modern ECT techniques, cognitive side-effects remain an important issue, although their nature and degree remains to be clarified fully. In these circumstances it is useful for clinicians to have guidance regarding what to tell patients and how to monitor these side-effects clinically.
On March 28, 2019, less than two weeks after the Christchurch, New Zealand massacre, the United Nations Security Council unanimously adopted Resolution 2462. It stands as a signal of the United Nations' continued recognition of the critical importance of finance in combatting and countering global terrorism. Unfortunately, it may also be an indication that states are not doing what they have been urged to do in previous resolutions. The text of 2462 and its preamble are riddled with language like “Reminding,” “Reaffirming,” “Encouraging,” and “Noting with Concern,” rather than with language and ideas that break new ground.
This introductory chapter of volume II of the Cambridge World History of Violence, which focuses on the thousand years between 500 and 1500, or what is also known as the Middle Millennium, examines .institutions and forms of violence in the geographical area including Japan and China, Central Asia, North Africa, and Europe, with two additional chapters extending coverage into Aztec and Mayan culture. The topics of this introduction are set in four contexts in which violence occurred across this broad chronology and vast territory. They are: the formation of centralized polities through war and conquest; institution building and ideological expression by these same polities; control of extensive trade networks; and the emergence and dominance of religious ecumenes. Attention is also given to the idea of how theories of violence are relevant to the specific historical circumstances discussed in the volume’s chapters. A final section on the depiction of violence, both visual and literary, demonstrates the ubiquity of societal efforts to confront meanings of violence during this longue durée.
Terrestrial plant macrofossils from the sedimentary record of Lake Suigetsu, Japan, provide the only quasi-continuous direct atmospheric record of radiocarbon (14C) covering the last 50 ka cal BP (Bronk Ramsey et al. 2012). Since then, new high precision data have become available on U-Th dated speleothems from Hulu Cave China, covering the same time range (Cheng et al. 2018). In addition, an updated varve-based chronology has also been published for the 2006 core from Lake Suigetsu (SG06) based on extended microscopic analysis of the sediments and improved algorithms for interpolation (Schlolaut et al. 2018). Here we reanalyze the radiocarbon dataset from Suigetsu based on the new varve counting information and the constraints imposed by the speleothem data. This enables the new information on the calendar age scale of the Suigetsu dataset to be used in the construction of the consensus IntCal calibration curve. Comparison of the speleothem and plant macrofossil records provides insight into the mechanisms underlying the incorporation of carbon into different types of record and the relative strengths of different types of archive for calibration purposes.
Violence permeated much of social life across the vast geographical space of the European, American, Asian and Islamic lands and through the broad sweep of what is often termed the Middle Millennium (roughly 500 to 1500). Focusing on four contexts in which violence occurred across this huge area, the contributors to this volume explore the formation of centralised polities through war and conquest; institution building and ideological expression by these same polities; control of extensive trade networks; and the emergence and dominance of religious ecumenes. Attention is also given to the idea of how theories of violence are relevant to the specific historical circumstances discussed in the volume's chapters. A final section on the depiction of violence, both visual and literary, demonstrates the ubiquity of societal efforts to confront meanings of violence during this longue durée.
New radiocarbon (14C) dates suggest a simultaneous appearance of two technologically and geographically distinct axe production practices in Neolithic Britain; igneous open-air quarries in Great Langdale, Cumbria, and from flint mines in southern England at ~4000–3700 cal BC. In light of the recent evidence that farming was introduced at this time by large-scale immigration from northwest Europe, and that expansion within Britain was extremely rapid, we argue that this synchronicity supports this speed of colonization and reflects a knowledge of complex extraction processes and associated exchange networks already possessed by the immigrant groups; long-range connections developed as colonization rapidly expanded. Although we can model the start of these new extraction activities, it remains difficult to estimate how long significant production activity lasted at these key sites given the nature of the record from which samples could be obtained.
Studies involving clinically recruited samples show that genetic liability to schizophrenia overlaps with that for several psychiatric disorders including bipolar disorder, major depression and, in a population study, anxiety disorder and negative symptoms in adolescence.
We examined whether, at a population level, association between schizophrenia liability and anxiety disorders continues into adulthood, for specific anxiety disorders and as a group. We explored in an epidemiologically based cohort the nature of adult psychopathology sharing liability to schizophrenia.
Schizophrenia polygenic risk scores (PRSs) were calculated for 590 European-descent individuals from the Christchurch Health and Development Study. Logistic regression was used to examine associations between schizophrenia PRS and four anxiety disorders (social phobia, specific phobia, panic disorder and generalised anxiety disorder), schizophrenia/schizophreniform disorder, manic/hypomanic episode, alcohol dependence, major depression, and – using linear regression – total number of anxiety disorders. A novel population-level association with hypomania was tested in a UK birth cohort (Avon Longitudinal Study of Parents and Children).
Schizophrenia PRS was associated with total number of anxiety disorders and with generalised anxiety disorder and panic disorder. We show a novel population-level association between schizophrenia PRS and manic/hypomanic episode.
The relationship between schizophrenia liability and anxiety disorders is not restricted to psychopathology in adolescence but is present in adulthood and specifically linked to generalised anxiety disorder and panic disorder. We suggest that the association between schizophrenia liability and hypomanic/manic episodes found in clinical samples may not be due to bias.
The term ‘mood stabiliser’ is ill-defined and lacks clinical utility. We propose a framework to evaluate medications and effectively communicate their mood stabilising properties – their acute and prophylactic efficacy across the domains of mania and depression. The standardised framework provides a common definition to facilitate research and clinical practice.
Declaration of interest
The Treatment Algorithm Group (TAG) was supported logistically by Servier who provided financial assistance with travel and accommodation for those TAG members travelling interstate or overseas to attend the meeting in Sydney (held on 18 November 2017). None of the committee were paid to participate in this project and Servier have not had any input into the content, format or outputs from this project.