We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure coreplatform@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Coronavirus disease 2019 (COVID-19) has rapidly spread globally, forcing countries to apply lockdowns and strict social distancing measures. The aim of this study was to assess eating habits and lifestyle behaviours among residents of the Middle East and North Africa (MENA) region during the lockdown. A cross-sectional study among adult residents of the MENA region was conducted using an online questionnaire designed on Google Forms during April 2020. A total of 2970 participants from eighteen countries participated in the present study. During the pandemic, over 30 % reported weight gain, 6·2 % consumed five or more meals per d compared with 2·2 % before the pandemic (P < 0·001) and 48·8 % did not consume fruits on a daily basis. Moreover, 39·1 % did not engage in physical activity, and over 35 % spent more than 5 h/d on screens. A significant association between the frequency of training during the pandemic and the reported change in weight was found (P < 0·001). A significantly higher percentage of participants reported physical and emotional exhaustion, irritability and tension either all the time or a large part of the time during the pandemic (P < 0·001). Although a high percentage of participants reported sleeping more hours per night during the pandemic, 63 % had sleep disturbances. The study highlights that the lockdown due to the COVID-19 pandemic caused a variety of lifestyle changes, physical inactivity and psychological problems among adults in the MENA region.
The DSM-IV criteria recognize the existence of obsessive–compulsive disorder (OCD) with poor insight. However, there is paucity of literature on the clinical correlates and treatment response in poor and good insight OCD. In this study, insight is measured by using the Brown Assessment of Beliefs Scale (BABS) developed specifically to assess insight. One hundred subjects with DSM-IV OCD were ascertained from the OCD clinic of a large psychiatric hospital in India. All subjects were evaluated extensively by using structured instruments and established measures of psychopathology. The subjects were treated with adequate doses of drugs for adequate period. The results showed that 25% of the subjects had poor insight. Poor insight was associated with earlier age-at-onset, longer duration of illness, more number of obsessive–compulsive symptoms, more severe illness and higher comorbidity rate, particularly major depression. Of the subjects who were treated adequately (N = 73), 44 (60%) were treatment responders. Poor insight was associated with poor response to drug treatment. In the step-wise logistic regression analysis, baseline BABS score was highly predictive of poor treatment response. Poor insight appears to be associated with specific clinical correlates and poor response to drug treatment. Further studies are needed in larger samples to replicate our findings.
To investigate a Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak event involving multiple healthcare facilities in Riyadh, Saudi Arabia; to characterize transmission; and to explore infection control implications.
Design
Outbreak investigation.
Setting
Cases presented in 4 healthcare facilities in Riyadh, Saudi Arabia: a tertiary-care hospital, a specialty pulmonary hospital, an outpatient clinic, and an outpatient dialysis unit.
Methods
Contact tracing and testing were performed following reports of cases at 2 hospitals. Laboratory results were confirmed by real-time reverse transcription polymerase chain reaction (rRT-PCR) and/or genome sequencing. We assessed exposures and determined seropositivity among available healthcare personnel (HCP) cases and HCP contacts of cases.
Results
In total, 48 cases were identified, involving patients, HCP, and family members across 2 hospitals, an outpatient clinic, and a dialysis clinic. At each hospital, transmission was linked to a unique index case. Moreover, 4 cases were associated with superspreading events (any interaction where a case patient transmitted to ≥5 subsequent case patients). All 4 of these patients were severely ill, were initially not recognized as MERS-CoV cases, and subsequently died. Genomic sequences clustered separately, suggesting 2 distinct outbreaks. Overall, 4 (24%) of 17 HCP cases and 3 (3%) of 114 HCP contacts of cases were seropositive.
Conclusions
We describe 2 distinct healthcare-associated outbreaks, each initiated by a unique index case and characterized by multiple superspreading events. Delays in recognition and in subsequent implementation of control measures contributed to secondary transmission. Prompt contact tracing, repeated testing, HCP furloughing, and implementation of recommended transmission-based precautions for suspected cases ultimately halted transmission.
This paper presents the concept of using cylindrical pins as short protuberances for trajectory control of a blunted cone in the supersonic and hypersonic regimes. Supersonic and hypersonic flow interactions for cylindrical protuberances, installed on a blunt cone are studied for their aerodynamic effects. The utility of these protuberances for aerodynamic control and trajectory shaping of a re-entry cone are explored. Static aerodynamic coefficients in the Mach range of 2–9·7 at various incidences are computed. The pressure distribution along the vehicle longitudinal axis in the presence of the pin-protuberance is studied using CFD analysis. With the altered pressure distribution, a net increase in the aerodynamic force is obtained which can be actively utilised for flight control and maneuvering of the vehicle during re-entry. After quantifying the aerodynamic effects of the protuberance, it is modelled and used as an effective actuation mechanism for flight feedback control. It is shown that this can work as an effective control device for Mach numbers less than five. An actuator design for insertion/retraction of the protuberance is presented and modelled, and a robust controller is synthesised which can in real time govern the position of the protuberance to control the flight attitude angle to achieve a desired trajectory. The controller takes in measurements of the vehicle’s pitch angle and actuates the pin height continuously to control the pitch angle to a desired value. The control performance is demonstrated on a high fidelity six degrees-of-freedom (6-DOF) nonlinear flight simulation.
Obsessive compulsive personality disorder (OCPD) is characterized by perfectionism, need for control, and cognitive rigidity. Currently, little neuropsychological data exist on this condition, though emerging evidence does suggest that disorders marked by compulsivity, including obsessive-compulsive disorder (OCD), are associated with impairment in cognitive flexibility and executive planning on neurocognitive tasks.
Aim
The current study investigated the neurocognitive profile in a nonclinical community-based sample of people fulfilling diagnostic criteria for OCPD in the absence of major psychiatric comorbidity.
Method
Twenty-one nonclinical subjects who fulfilled Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for OCPD were compared with 15 healthy controls on selected clinical and neurocognitive tasks. OCPD was measured using the Compulsive Personality Assessment Scale (CPAS). Participants completed tests from the Cambridge Automated Neuropsychological Test Battery including tests of set shifting (Intra-Extra Dimensional [IED] Set Shifting) executive planning (Stockings of Cambridge [SOC]), and decision making (Cambridge Gamble Task [CGT]).
Results
The OCPD group made significantly more IED-ED shift errors and total shift errors, and also showed longer mean initial thinking time on the SOC at moderate levels of difficulty. No differences emerged on the CGT.
Conclusions
Nonclinical cases of OCPD showed significant cognitive inflexibility coupled with executive planning deficits, whereas decision-making remained intact. This profile of impairment overlaps with that of OCD and implies that common neuropsychological changes affect individuals with these disorders.
Los criterios del DSM-IV reconocen la existencia del trastorno obsesivo-compulsivo (TOC) con poca conciencia de enfermedad. Sin embargo, hay una escasez de publicaciones sobre los correlatos clínicos y la respuesta al tratamiento en TOC con poca conciencia de enfermedad y con buena conciencia de enfermedad. En este estudio, la conciencia de enfermedad se mide utilizando la Escala de Evaluación de las Creencias de Brown (BABS) desarrollada específicamente para evaluar la conciencia de enfermedad. Se comprobó a cien sujetos con TOC del DSM-IV de la clínica de TOC de un gran hospital psiquiátrico en India. Todos los sujetos recibieron una evaluación arnplia utilizando instrumentos estructurados y medidas establecidas de trastornos psicopatológicos. Se trató a los sujetos con dosis adecuadas de fármacos durante un periodo adecuado. Los resultados mostraron que el 25% de los sujetos tenían poca conciencia de enfermedad. La poca conciencia de enfermedad se asociaba con edad anterior en el comienzo, duración más larga de la enfermedad, mayor número de síntomas obsesivo-compulsivos, enfermedad más grave y tasa más alta de comorbilidad, particularmente de depresión mayor. De los sujetos que recibieron tratamiento adecuado (n = 73), 44 (el 60%) respondieron al tratamiento. La poca conciencia de enfermedad se asociaba con mala respuesta al tratamiento farmacológico. En el análisis de regresión logística paso a paso, la puntuación de la BABS en la línea de base predecía muy bien la mala respuesta al tratamiento. La poca conciencia de enfermedad parece asociarse con correlatos clínicos específicos y mala respuesta al tratamiento farmacológico. Se necesitan más estudios en muestras mayores para replicar nuestros hallazgos.
The majority of high-efficiency space solar cells being produced today are based on multi-junction devices of lattice-matched III-V materials. An alternative which has been receiving an increasing amount of attention is the lattice mis-matched or metamorphic approach to multi-junction cell development. In the metamorphic triple junction cell under development by ERI and its partners, the InGaAs junction (bottom cell) of the three-cell stack is the current limiting entity, due to the current matching which must be maintained through the device. This limitation may be addressed through the incorporation of InAs quantum dot array into the depletion region of an InGaAs cell. The InAs quantum dots in the InGaAs cell will provide sub-gap absorption and thus improve its short circuit current. This cell could then be integrated into the three-cell stack to achieve a space solar cell whose efficiency exceeds current state-of-the-art standards. A theoretical estimate predicts that a InGaAlP(1.95eV)/InGaAsP(1.35 eV)/InGaAs(1.2 eV) triple junction cell incorporating quantum dots to improve the bottom cell current would have an efficiency exceeding 40%. In addition, theoretical estimates have demonstrated that the use of quantum dot structures may also hold other cell benefits such as improved temperature coefficients and better radiation tolerance, which are especially important for utilization in space. As a first step towards achieving that goal, we have initiated the development of InAs quantum dots on lattice-mismatched InGaAs (1.2 eV bandgap) grown epitaxially on GaAs by metallorganic vapor phase epitaxy (MOVPE). These quantum dots have been characterized via photoluminescence (PL) and atomic force microscopy (AFM). A correlation exists between the quantum dot size and resulting optical band structure and can be controlled via the synthesis parameters. Quantum dots were incorporated into prototype InGaAs devices. A comparison of the resulting photovoltaic efficiency under simulated 1 sun intensity and air mass zero (AM0) illumination and spectral response demonstrated that an improvement in the long-wavelength photoconversion efficiency was achieved through the incorporation of the InAs quantum dots.
Recommend this
Email your librarian or administrator to recommend adding this to your organisation's collection.