A novel shape penta-band microstrip patch antenna is presented in this paper. The proposed antenna shows five operating frequencies and can be used for various wireless applications, i.e. 2.58 GHz for non-direct line of sight, wireless Internet service providers, and compatible with Navini Networks; 3.17 and 3.42 GHz for WiMAX; 4 GHz for C-band application such as weather radar systems; and 5.3 GHz for higher WLAN. Very small frequency ratios of the values 1.2286, 1.078, 1.169, and 1.325 are achieved between two consecutive resonant frequencies. Antenna design techniques for achieving five bands are presented and discussed step by step. The analysis is done by Ansoft HFSS v.15, and results are verified with experimental results of fabricated prototypes.