A new device is presented for the combinatorial analysis of complex nano-scale material systems. The parallel nano-differential scanning calorimeter (PnDSC) is a micro-machined array of calorimetric cells. This new approach to combinatorial calorimetry should expedite the analysis of nano-scale material thermal properties. A power compensation differential scanning calorimetry measurement, not yet performed on a device of this type, is described. A NiTi specific heat measurement demonstrates the scanning calorimetry capability of the PnDSC.