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To examine the quality of life (QOL) of parents of children with a specific mental disorder (any age).
Relevant articles were searched using different databases. Articles were included that compared the QOL of parents with mentally-ill children to parents of healthy controls or norm values or provided the required data for this comparison. A meta-analysis was conducted to obtain an overall mean effect size estimate. Additional analyses were performed to assess publication bias and moderation.
Twenty-six out of 10 548 articles met the pre-defined inclusion criteria. Most of these studies focused on attention-deficit/hyperactivity disorder or autism spectrum disorder, used clinical samples that mainly included males and young children and studied the QOL of mothers. The meta-analysis revealed that parents of mentally-ill children are experiencing a clinically relevant reduction in their QOL relative to parents of healthy children and norm values (g = −0.66).
The compromised QOL of parents of mentally-ill children needs to be considered and addressed by health professionals who are in contact with them. The paper provides insights into existing research gaps and suggests improvements for subsequent work.
The Learning Health System Network clinical data research network includes academic medical centers, health-care systems, public health departments, and health plans, and is designed to facilitate outcomes research, pragmatic trials, comparative effectiveness research, and evaluation of population health interventions.
The Learning Health System Network is 1 of 13 clinical data research networks assembled to create, in partnership with 20 patient-powered research networks, a National Patient-Centered Clinical Research Network.
Results and Conclusions
Herein, we describe the Learning Health System Network as an emerging resource for translational research, providing details on the governance and organizational structure of the network, the key milestones of the current funding period, and challenges and opportunities for collaborative science leveraging the network.
Published in English in 1884, this is the posthumous third edition of an 1862 study by the German orientalist Martin Haug (1827–76). He produced this groundbreaking analysis and comparison of Sanskrit and the Avesta while professor of Sanskrit at the Government College of Poona. His time in India enabled him to make an unprecedented study of Zoroastrian texts, becoming the first to translate the seventeen Gathas into a European language, thereby helping to highlight that they were composed by Zoroaster. Edward William West (1824–1905), an engineer and self-taught orientalist, met Haug in India. Having read this work's first edition, he was inspired to study further the Pahlavi language. On his and Haug's return to Europe in 1866, they worked closely together in translating and publishing Zoroastrian texts. West's edition of Haug's Essays includes several updates, unpublished papers from Haug's collection, appendices of further translations, and a biography of the author.