The incidence of depression is higher in women than men but the reverse
pattern is seen with suicide. In a cohort of 50 692 Norwegians we found that
suicide risk associated with comorbid anxiety and depression was two-fold
higher in men (OR=7.4, 95% CI 3.1-17.5) than women (OR=2.9, 95% CI
0.8-10.6), although statistical evidence for a difference was weak (P=0.4).
If real, these gender differences could reflect either a more severe symptom
profile in men with self-reported anxiety and depression, perhaps because of
gender differences with regard to the stigma associated with mental illness,
or gender differences in the way men respond to mental illness (e.g.