This study investigated fatigue and anger in people with SCI. Participants were 27 adults with SCI living in the community (males = 26, females = 1; mean age = 50 years, SD = 9.47 years) and a comparison group of 27 other adults without SCI. Data about their experience of fatigue and anger were collected using the Chalder Fatigue Scale and the Profile of Mood States. Kruskal-Wallis ANOVA by ranks and chi-square analyses were used to determine whether the SCI participants had elevated levels of fatigue and anger than the typical or noninjured community group. Persons with SCI reported significantly elevated fatigue and elevated levels of anger than typical others. These findings are discussed with reference to adjustment following SCI, and interpreted in light of the Stress Appraisal and Coping Model (SAC) of adjustment following SCI.