The major part of groundwater contaminants strongly interact with soils and aquifer rocks. Therefore sorption processes on porous matrix are of utmost importance in the frame of the nuclear waste disposal. The objectives of this study were to evaluate sorption uptake by silica sand of some safety-relevant metal ions such as Cs+, Sr2+, Cu2+, Ni2+ and to investigate the existence of competitive sorption processes between these ions. To this aim, kinetic and equilibrium, mono-component and multi-component, batch experiments were carried out in order to study: i) the influence of metal concentration, pH and contact time, on sorption onto silica sand of the above ions in aqueous solution, and ii) the presence of competition phenomena. Sorption data were well fitted by Langmuir and Freundlich models. Multi-component tests show that the uptake of each ion is reduced in presence of other ions in solution with respect to mono-component batch tests results and that competition between species appears influenced by the equilibrium times of the single species in solution and by pH.