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4 results

  • Nutritional status is strongly correlated with grip strength and depression in community-living elderly Japanese

  • Tomoko Kaburagi, Reiko Hirasawa, Haruka Yoshino, Yukino Odaka, Mariko Satomi, Mana Nakano, Eka Fujimoto, Kazuyuki Kabasawa, Kazuto Sato
  • Journal:
    Public Health Nutrition / Volume 14 / Issue 11 / November 2011
    Published online by Cambridge University Press:
    23 March 2011, pp. 1893-1899
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  • Objectives

    To evaluate the utility of the Mini-Nutritional Assessment (MNA) in assessing nutritional, physical and psychosocial functions in community-living elderly individuals.

    Design

    A cross-sectional study of elderly individuals investigated in August 2007 and August–September 2008. Nutritional status was assessed using serum biomarkers, anthropometric measurements and the MNA. Physical function was assessed by measuring grip strength and both usual and maximum walking speeds. The Geriatric Depression Scale (GDS) was used to measure the individual's depressive state.

    Setting

    Elder-care facilities in Tokyo, Japan.

    Subjects

    Community-living elderly individuals aged ≥65 years (n 130).

    Results

    The MNA evaluation classified twenty-seven (20·8 %) individuals as being at risk for malnutrition (MNA score ≤23·5); these at-risk individuals included a high proportion of the elderly aged ≥75 years. MNA scores correlated with nutritional biomarkers (total protein, albumin, cholinesterase, Hb) and anthropometric measurements (triceps skinfold, subscapular skinfold, mid-arm muscle area) and exhibited a strong correlation with grip strength and GDS score. Multivariate analysis revealed that grip strength, GDS score, marital status and maximum walking speed are strong predictors of MNA score.

    Conclusions

    The MNA is considerably useful in providing a comprehensive assessment of nutritional status in elderly, community-living Japanese. However, larger-scale epidemiological studies are needed to determine the utility and the appropriate cut-off point of the MNA as a screen for risk of malnutrition.

  • Analysis of cyclic feed intake in rats fed on a zinc-deficient diet and the level of dihydropyrimidinase (EC 3.5.2.2)

  • Nanaya Tamaki, Shigeko Fujimoto-Sakata, Mariko Kikugawa, Masae Kaneko, Satomi Onosaka, Tatsuya Takagi
  • Journal:
    British Journal of Nutrition / Volume 73 / Issue 5 / May 1995
    Published online by Cambridge University Press:
    09 March 2007, pp. 711-722
    Print publication:
    May 1995
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  • The body weight and feed intake of rats fed on a Zn-deficient diet for 28 d were reduced compared with those of control rats. The feed intakes of the Zn-deficient and control groups during the period were 10·2 (SE 0·3) and 15·7 (SE 0·2) g/d respectively. Cyclic variations in feed intake and body-weight changes were found in analysis not only of all the data for five rats but also that in each individual rat. Cosinor analysis revealed that the cyclical period of both the feed intake and body-weight change in the Zn-deficient rats was 3·5 (SE 0·1) d. The mesor and amplitude value of the feed intake in the Zn-deficient rats was 10 1 (SE 0·4) g/d and 3·5 (SE 0·5) g/d respectively, and that of body-weight change was 1·4 (SE 0·1) g/d and 7·9 (SE 1·3) gObihiro d respectively. Among pyrimidine-catabolizing enzymes, dihydropyrimidinase (EC3.5.2.2) activity showed significantretardation in the Zn-deficient rat liver with decrease of the enzyme protein. The ratio of apo-form to holo-form dihydropyrimidinase in the liver was not affected by the Zn-deficient diet.