To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure email@example.com
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Antonio V. Delgado-Escueta, Comprehensive Epilepsy Program, UCLA and VA Greater Los Angeles Healthcare System, CA, USA,
Marco T. Medina, Department of Neurology, Autonomous University, Tegucigalpa, Honduras,
Maria Elisa Alonso, Department of Genetics National Institute of Neurology and Neurosurgery, Mexico City, Mexico,
G. C. Y. Fong, Division of Neurology, University Department of Medicine, Queen Mary Hospital, Hong Kong
This chapter initially reviews the new advances in molecular genetics of idiopathic epilepsies in infants, children, adolescents and adults and provides a progress report on the search for chromosomal loci of epilepsy syndromes. After presenting an overview on the molecular genetics of idiopathic epilepsies, this chapter focuses on phenotypes and genotypes of genetic epilepsies that are commonly mistaken for movement disorders.
Understanding the genotypes and phenotypes of movement disorders and epilepsies in infants, children and adolescents is important because some motor signs of idiopathic epilepsies of infants, children and adolescents are mistaken for movement disorders and some movement disorders of children and adolescents are mistaken for the epilepsies. Moreover, understanding the new advances in the molecular genetics of movement disorders and epilepsies is important because they provide us with more than a glimpse of the new practice of molecular neurology. The epilepsies have traditionally been classified and subtyped on the basis of clinical and neurophysiologic concepts. The complexity and variability of phenotype and overlapping clinical features limit the resolution of phenotype-based classification and confounds epilepsy nosology. Identification of tightly linked epilepsy DNA markers and discovery of epilepsy causing mutations provide a basis for refining the classification of epilepsies.
Table 27.1 lists some of the epilepsies commonly mistaken for movement disorders and Table 27.2 gives some descriptions used by the referring physicians that made them mistakenly suspect a movement disorder in patients with juvenile myoclonic epilepsy (JME). Patients initially diagnosed to have movement disorders were verified to have myoclonias and rapid spike-wave complexes on CCTV-EEG telemetry.
Email your librarian or administrator to recommend adding this to your organisation's collection.