For two decades, the Hopi Cultural Preservation Office has worked with archaeologists to co-create knowledge about the past and document contemporary values associated with heritage sites. Much of this work has been accomplished within the framework of research mandated by the National Historic Preservation Act and National Environmental Policy Act. Here we describe a case study that illustrates the processes of this community-based participatory research, including research design, implementation of fieldwork, peer review of research findings, and reporting. The case study is a project conducted in 2014 by the Hopi Tribe in partnership with Anthropological Research, LLC, to investigate traditional cultural properties associated with an Arizona Public Service Company transmission line. The Hopi Tribe’s collaborative research with archaeologists provides intellectual benefits for the management of archaeological resources and the humanistic and scientific understanding of the past.