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Trypanosoma cruzi has three biochemically and morphologically distinct developmental stages that are programmed to rapidly respond to environmental changes the parasite faces during its life cycle. Unlike other eukaryotes, Trypanosomatid genomes contain protein coding genes that are transcribed into polycistronic pre-mRNAs and have their expression controlled by post-transcriptional mechanisms. Transcriptome analyses comparing three stages of the T. cruzi life cycle revealed changes in gene expression that reflect the parasite adaptation to distinct environments. Several genes encoding RNA binding proteins (RBPs), known to act as key post-transcriptional regulatory factors, were also differentially expressed. We characterized one T. cruzi RBP, named TcZH3H12, which contains a zinc finger domain and is up-regulated in epimastigotes compared to trypomastigotes and amastigotes. TcZC3H12 knockout (KO) epimastigotes showed decreased growth rates and increased capacity to differentiate into metacyclic trypomastigotes. Transcriptome analyses comparing wild type and TcZC3H12 KOs revealed a TcZC3H12-dependent expression of epimastigote-specific genes such as genes encoding amino acid transporters and proteins associated with differentiation (PADs). RNA immunoprecipitation assays showed that transcripts from the PAD family interact with TcZC3H12. Taken together, these findings suggest that TcZC3H12 positively regulates the expression of genes involved in epimastigote proliferation and also acts as a negative regulator of metacyclogenesis.
To investigate the role of perfectionism in the development of disordered eating behaviours.
Method:
382 female university students completed the Hewitt & Flett MPS and the EAT-40 at baseline, one year after (T1) and two years later (T2).
Results:
Perfectionism at baseline was significantly associated with long-term abnormal eating attitudes/behaviours. Self-Oriented Perfectionism (SOP) and Socially Prescribed Perfectionism (SPP) were significant predictors of disordered eating behaviours. SOP at baseline was predictive of diet concerns, at T1 and T2. Baseline SPP was correlated with overall eating disturbance at T1 and T2. Regression analysis revealed that only SPP was a significant predictor of bulimic behaviours and social pressure to eat at T1, but not at T2.
Conclusion:
Our findings contribute to a more clear understanding of the association between perfectionism and eating disorders. SOP and SPP were prospectively associated with abnormal eating attitudes/behaviours and SOP was found to be predictive of diet concerns.
Cognitive impairment is increasingly regarded as a core aspect of schizophrenia. It is associated with poor functional outcome, may represent a rate limiting factor in rehabilitation programs and is not largely influenced by pharmacological interventions.
Several studies suggest the efficacy of cognitive training programs and advice their inclusion in treatment strategies, while others discourage clinical application.
We recently completed a study involving three Mental Health Departments located in the South of Italy and coordinated by the Department of Psychiatry of the University of Naples SUN. Fifty-eight patients with either a diagnosis of schizophrenia or schizoaffective disorder were recruited and randomly allocated to one of two rehabilitation programs: Social Skill Training (SST) + Computerized Cognitive Training (CCT) (Group A) and usual rehabilitation activities of the Department (Group B). The active treatment phase lasted 6 months. Psychopathological aspects, as well as psychosocial and neurocognitive functioning, were assessed both before and after treatment. Group A subjects participated in two one-hour sessions of CCT and one two-hour session of SST. Group B patients spent an equivalent amount of time in the usual rehabilitation activities.
The two groups did not differ on baseline clinical, neurocognitive and psychosocial variables.
At the end of treatment, a worsening of the negative dimension was observed in group B, but not in group A, in which a significant improvement of two psychosocial indices (participation in family life and availability to work) was found.
The experimental program (SST+CCT) was more effective than usual rehabilitation activities of the departments.
To investigate associations between perfectionism dimensions and psychological distress 421 pregnant women (M=29.8, SD=4.48 years) completed measures of Self-Oriented Perfectionism (SOP), Socially-Prescribed Perfectionism (SPP) (MPS; Hewitt & Flett, 1991; Soares et al., 2003), mood (POMS; McNair et al., 1971; Azevedo et al., 1991) and depressive symptomatology (BDI-II; Beck et al., 1996; Coelho et al., 2002).
Methods:
A 2-factor model of Perfectionism with SOP and SPP dimensions and a 3-factor model with SOP, SPP-Others’ High Standards and SPP-Conditional Acceptance factors were explored. Correlations and Linear Regressions were calculated between perfectionism factors and mood variables/depressive symptoms.
Results:
Higher levels of SPP factors were in general associated with increased Anxiety, Depression, Anger, Fatigue and Confusion, with decreased Vigour and with more severe depressive symptomatology. SPP dimension and both SPP sub-scales explained depressive symptoms.
Conclusion:
Our results, in contrast with those from the study of Campbell and DiPaula (2002) did not confirm a preferential association between SPP-Conditional Acceptance and psychological distress (PD), revealing that both components of SPP were associated with PD.
Bipolar Disorder is a serious, common and disabling mental disorder which is associated to high morbidity and high suicide attempt rates.
Objectives
To identify clinical and social-demographic variables associated to suicidal behaviour in Bipolar Disorder.
Methods
The samples comprises 124 patients (62.1% females) diagnosed with Bipolar Disorder (ICD-10 diagnosis following DIGS/OPCRIT). The variables selected to the analysis were extracted from DIGS and OPCRIT.
Results
Suicidal behaviour occurs in 27.1% of the patients; the most used method was voluntary drug poisoning; it's more frequent in females, with males using more violent methods - remaining results still unavailable.
Conclusions
This study identifies several clinical and social-demographic variables that can help the clinician to delineate a suicidal profile among his Bipolar patients, hence improving his ability to develop an early intervention plan and suicide prevention strategies.
Several studies provided evidence that relationship of cognitive impairment with social functioning is stronger than that of psychopathology. In a group of 88 subjects with schizophrenia or schizoaffective disorders we found that verbal memory, executive function and sustained attention indices explained 19.9% of the global disability variance, while negative symptoms explained 4.4% of the variance.
Based on these data our group designed an individualized rehabilitation program including two one-hour sessions of computerized cognitive training and one two-hour session of social skills training per week (Social Skills And Neurocognitive Individualized Training, SSANIT).
In the present study the efficacy of this rehabilitation program was investigated in 58 subjects with chronic schizophrenia or schizoaffective disorder. Patients were recruited in three Mental Health Departments located in the South of Italy and randomly allocated to one of two rehabilitation programs: SSANIT or Usual Rehabilitation Activities (URA) of each department. The active treatment phase lasted 6 months.
At the end of treatment a significant improvement of psychosocial functioning (global psychosocial index, participation in family life and availability to work) was found in the SSANIT but not in the URA group; furthermore a worsening of the negative dimension was observed in the URA, but not in the SSANIT group.
According to our findings, the SSANIT program is more effective than the rehabilitation activities usually implemented in Mental Health Departments (e.g. carpentry and decoupage).
To investigate the role of perfectionism in the development of disordered eating behaviours.
Method:
382 female university students completed the Hewitt & Flett MPS and the EAT-40 at baseline, one year after (T1) and two years later (T2).
Results:
Perfectionism at baseline was significantly associated with long-term abnormal eating attitudes/behaviours. Self-Oriented Perfectionism (SOP) and Socially Prescribed Perfectionism (SPP) were significant predictors of disordered eating behaviours. SOP at baseline was predictive of diet concerns, at T1 and T2. Baseline SPP was correlated with overall eating disturbance at T1 and T2. Regression analysis revealed that only SPP was a significant predictor of bulimic behaviours and social pressure to eat at T1, but not at T2.
Conclusion:
Our findings contribute to a more clear understanding of the association between perfectionism and eating disorders. SOP and SPP were prospectively associated with abnormal eating attitudes/behaviours and SOP was found to be predictive of diet concerns.
This study examines the relationship between the personality traits of Neuroticism and Extroversion and sleep patterns and others sleep behaviours in medical students.
Method:
Neuroticism and Extroversion were assessed using the Portuguese version of the Eysenck Personality Inventory. Sleep was assessed with a self-response questionnaire covering a wide range of sleep-wake habits and difficulties. A factor analysis with varimax rotation was performed with seventeen items of the questionnaire and four factors were extracted: Sleep Disturbance, Sleep Timing, Insufficient Sleep and Dreams/Nightmares. A total of 203 third year medical students (127 females, 62.6%) mean age 20.01 (SD=1.09; Range=18-24) participated in the study.
Results:
There were no significant gender differences in Neuroticism and Extroversion mean scores (Neuroticism: p=.454; Extroversion: p=.891). Extroversion was significantly correlated with Sleep Timing (p=.000), whereasthere was a trend for Neuroticism to be associated with Sleep Disturbance (p=.095). Concerning the relationship of Neuroticism and Extroversion mean scores with other Sleep problems, Neuroticism was found associated with concentration difficulties in the morning (p=.006), inadequate sleep duration (p=.001), sleep problems (p=.012), and use of sleep medication (p=.052). No significant associations were found with Extroversion.
Conclusion:
Neuroticism was significantly associated with sleep problems, use of sleep medication, inadequate sleep duration, and concentration difficulties in the morning. Extroversion was correlated only with later Sleep Timing.
The role of perfectionism as a correlate of perinatal depressive symptomatology, and as a predictor of postpartum depressive disorder was examined.
Methods
386 women in their third trimester of pregnancy (mean age = 30.08 years; SD = 4.205; range = 19–44) completed the Portuguese versions of Multidimensional Perfectionism Scale, Beck Depression Inventory-II/BDI-II, Postpartum Depression Screening Scale/PDSS and three additional questions evaluating anxiety trait, life stress perception and social support. Diagnoses of depression (ICD-10/DSM-IV) were obtained using the Portuguese version of the Diagnostic Interview for Genetic Studies/OPCRIT system. Women who were clinically depressed in pregnancy (ICD-10/DSM-IV) were excluded from the analysis.
Results
Self-Oriented Perfectionism/SOP and Socially Prescribed Perfectionism/SPP subcomponents were significant correlates of depressive symptomatology (BDI-II/PDSS) in pregnancy. SPP-Others High Standards/OHS was a significant predictor of postpartum depressive symptomatology (BDI-II/PDSS), and SPP-Conditional Acceptance/CA was a predictor of postpartum depressive symptomatology (PDSS). None of the perfectionism subscales predicted postpartum depressive disorder (ICD-10/DSM-IV).
Conclusions
SOP and SPP have shown to be relevant correlates of depressive symptomatology in pregnancy. In the present study, SPP-OHS and SPP-CA were also significant correlates of perinatal depressive symptomatology, as well as important risk factors for depressive symptomatology in postpartum. Perfectionism subscales were not significant predictors of postpartum depressive disorder (ICD-10/DSM-IV). While SPP maladaptive influence was supported, SOP was shown to be more heterogeneous in its consequences. These findings may have important implications both for clinical practice and for research.
The objective of this study was to examine the sleep patterns of medical students and its associations with significant health behaviours.
Methods:
Sleep was assessed with a self-response questionnaire covering a wide range of sleep-wake habits and difficulties. A factor analysis with varimax rotation was performed with seventeen items of the questionnaire and four factors were extracted: Sleep Disturbance, Sleep Timing, Insufficient Sleep and Dreams/Nightmares. The questionnaire also included questions on coffee use, cigarette smoking, alcohol intake and physical exercise. The sample consisted of 212 females (M age=20.32 years, SD=1.26) and 128 males (M age=20.19 years, SD=1.23) third year medical students.
Results:
Habitual alcohol intake was reported by 6.5% of the students (males=14.8% vs females=1.4%; p=.000) and regular physical exercise by 37.9% (males=47.7% vs females=32.1%; p=.004); The mean number of coffee cups used per day was 2.16±1.16 (males M=2.18±1.35 vs females M=2.13±1.03; NS) and the mean number of cigarettes smoked per day was 3.69±5.71 (males M=4.41+6.55 vs females M=3.25±5.10; NS). Students who regularly practice physical exercise reported less Sleep Disturbance (p=.004). Habitual alcohol intake was significantly associated with Sleep Timing (p=.051) and Insufficient Sleep (p=.007). Significant correlations were also found between cigarette smoking and Sleep Timing (p=.000), Dreams/nightmares (p=.023) and Insufficient Sleep (p=.001). Coffee use was correlated only with Sleep Timing (p=.000).
Conclusion:
In this sample of healthy young adults habitual alcohol intake and cigarette smoking was associated with Insufficient Sleep and regular physical exercise was associated with less Sleep Disturbance.
Screening for perinatal depression is essential. The Postpartum Depression Screening Scale (PDSS; Beck & Gable, 2002) is a self-report instrument, composed of 35 items. The Portuguese version of the PDSS revealed to be a valid instrument to screen for perinatal depression (Pereira et al., 2010a,b).
Objectives
To develop PDSS short version and to determine its cut-off points and associated conditional probabilities to screen for depression according to DSM-IV and ICD-10 criteria.
Methods
Participants were 452 women in their third month post-partum (M = 13.07 weeks post-partum; SD = 1.808). All women completed the Portuguese PDSS and were interviewed using the Mood Disorders Section/Diagnostic Interview for Genetic Studies. To select items for the short version the items that showed the highest correlations with their respective seven dimension scores were retained. ROC analysis was applied and both cut-off points and associated conditional probabilities adjusted to the real prevalence were determined.
Results
For major depression/DSM-IV the cut-off point of 15, resulted in sensitivity of 77.8%, specificity of 88.9%, positive predictive value (PPV) of 21.7% and negative predictive value (NPV) of 98.9%; for depressive disorder/ICD-10 the cut-off point of 14 determined sensitivity 77.3%, specificity 84.0%, PPV 19.7%, NPV 98.6%; for mild/moderate depression with somatic syndrome or severe depression without psychotic symptoms/ICD-10 the cut-off point of 18 was associated to sensitivity 91.7%, specificity 94.5%, PPV 31.4% and NPV 99.8%.
Conclusions
The Portuguese short version of PDSS is a good alternative to the 35-items version, equally valid and precise, but more economic, faster and easier.
The aim of the present study was to determine the frequency of emotional and disruptive behaviours and the rates of hyperactivity, conduct and emotional problems in school-aged children. The Rutter Children’s Behaviour Questionnaire for completion by teachers was used to assess psychiatric symptoms. A total deviance score is derived from the sum of scores for the individual items (n= 26). An emotional sub-score can be obtained from the sum of scores of four items (worried, miserable, fearful, tears on arrival at school), a conduct sub-score obtained from the sum of scores of six items (destructive, fights, disobedient, lies, steals, bullies) and a hyperactivity sub-score obtained from the sum of scores of three items (restless/overactive, poor concentration, fidgety/squirmy). The sample comprised 877 children (446 girls) with an age range between 6 and 11 years. Compared to girls, boys showed a significantly higher frequency of restless/overactive (15.8% vs. 5.8%), fidgety/squirmy (9.3% vs. 3.6%), fights (6.3% vs. 2.2%), disobedient (6.0% vs. 2.7%), bullies (5.3% vs. 2.0%) and irritable (5.1% vs. 1.8%) behaviours. Rates of conduct and hyperactivity behavioural problems were also significantly more frequent in boys than in girls (conduct problems: 17.9% vs. 8.1%; hyperactivity problems: 20.4% vs. 9.6%). The high rates of disruptive behaviours and problems in boys are in accordance with the literature.
Screening for postpartum depression has been considered essential. The Postpartum Depression Screening Scale (PDSS; Beck & Gable, 2002) is a self-report instrument, composed of 35 items placed in the specific context of new maternity. The aim of the present study was to determine, for the first time, PDSS cut-off points (adjusted to the real prevalence) and associated conditional probabilities to screen for depression in the post-partum, according to DSM-IV and ICD-10 criteria. Participants were 452 women, mean age=30.52 years (SD=4.176) in their third month post-partum (M=13.07 weeks post-partum; SD=1.808). All women completed the Portuguese version of the PDSS and were interviewed using the Mood disorders Section/Diagnostic Interview for Genetic Studies. ROC analysis was applied and both cut-off points and associated conditional probabilities adjusted to the real prevalence were determined. For major depression/DSM-IV the cut-off point of 69 (prevalence - 4.0%), resulted in sensitivity of 77.8%, specificity of 86.9%, positive predictive value (PPV) of 19.7% and negative predictive value (NPV) of 98.9%; for depressive disorder/ICD-10 the cut-off point of 67 (prevalence - 4.9%) determined sensitivity 77.3%, specificity 85.3%, PPV 21.2%, NPV 98.6%; for mild/moderate depression with somatic syndrome or severe depression without psychotic symptoms/ICD-10 (prevalence - 2.7%) the cut-off point of 80 was associated to sensitivity 91.7%, specificity 94.3%, PPV 30.6% and NPV 99.8%.In conclusion, the Portuguese version of the PDSS revealed to be a valid instrument to screen for depression in the post-partum.
*Data for this study were drawn from a research project on Postpartum Depression and Sleep, FCT (POCI/SAU-ESP/57068/2004).
Insight and treatment adherence in serious mental illness, namely psychotic disorders, are well recognized as strong predictors of prognosis; several psychometric instruments have been developed for their evaluation.
Objectives and aims
To analyze the relation between self and hetero-evaluated insight and treatment attitudes in a clinical sample of psychiatric patients, besides assessing it's clinical correlates and relevance.
Methods
60 patients with serious mental illness (schizophrenia and bipolar disorder with psychotic features) were assessed using the Portuguese versions of the ‘Insight Scale' (IS), ‘Medication Adherence Rating Scale’ (MARS) and ‘Insight and Treatment Attitudes Questionnaire’ (ITAQ). General psychopathology and functioning scales were also applied, such as the BPRS, BDI-II and FAST. Relevant sociodemographic and clinical variables were also obtained. Statistical analysis was conducted using SPSS version 19.
Results
Self-reported insight using the IS was not correlated with the insight subscale of the ITAQ, a hetero-evaluation instrument. Similarly, we found no correlation regarding attitudes to treatment when comparing self-report (MARS) and hetero- evaluation (treatment attitudes subscale of the ITAQ). Nonetheless, patients with a history of medication non-compliance and worse clinical outcomes had significantly lower (p< .05) scores in hetero-evaluation measures of insight and treatment attitudes (ITAQ), yet exhibited no differences in the self-evaluation measures of those dimensions.
Discussion and conclusions
Insight and treatment attitudes assessments can be valuable in clinical practice, contributing to decisions in both in- and outpatient settings involving treatment planning and level of monitoring. Clinician-rated instruments are probably more reliable, with clearer prognostic relevance.
The Maudsley Obsessional-Compulsive Inventory (MOCI; Hodgson & Rachman, 1977) continues to be a widely used self-report measure of obsessive-compulsive symptoms. It has been translated into at least seven languages and the respective validations have resulted in good psychometric characteristics. It has not been validated to the Portuguese population yet.
Objectives
To investigate the psychometric properties and factorial structure of the MOCI Portuguese version.
Methods
The process of translation/re-translation followed the required steps. The MOCI was administered to a community sample of 217 first year university students (178 girls; 82.0%). The mean age was 18.50 (± 2.345: range: 17–35). To study the temporal stability 166 (135 girls; 81.3%) respondents answered the questionnaires again after approximately six weeks.
Results
The MOCI Cronbach's a was good (.79). The test-retest coefficient for the total score was high (.79; p < .001). An inspection of the Cattel's Scree plot and also of the item's content led us to select a three factors structure, which explained variance was of 29.17%: Factor (F) 1 “Doubting and Rumination” (VE = 15.43%; a = .72); F2 “Checking” (VE = 7.65%; a = .66) and F3 “Cleaning” (VE = 6.08%; a = .63). Temporal stability of F1, F2 and F3 were high: .67, .65 and .73 (all p < .001), respectively. Pearson correlations between factors were moderate and significant (≥.30).
Conclusions
The MOCI Portuguese version has good psychometric properties and its factorial structure is in accordance with those reported by other groups. It could be very useful to clinical and epidemiological purposes, as well as to transcultural studies.
Perfectionism has been a topic of increased interest in recent years. Findings from the literature have shown that perfectionism is associated in the development and maintenance of a wide range of psychopathological conditions.
Objectives/aims
1) to analyze the psychometric properties of the Portuguese version of the Frost Multidimensional Perfectionism Scale (FMPS);
2) to explore the associations between perfectionism dimensions and positive/negative affectivity.
Methods
217 students from two Portuguese Universities filled in the FMPS and the Profile of Mood States (POMS). A subgroup (n=166) completed a retest of the FMPS with a four weeks interval.
Results
Scale reliability was good (Cronbach alpha = .857). Corrected item-total correlations ranged from .019 and .548, and were higher than .2 for most of the items. Test-retest reliability suggested a good temporal stability for FMPS total score (r=.765). A principal component analysis with Varimax rotation was performed and based on Scree plot, two robust factorial structures were suggested (four and six factors). The more maladaptive dimensions of perfectionism were significantly and positively associated with negative affect and negatively associated with positive affect. Depression and anxiety/hostility dimensions are both positively associated with concern over mistakes (respectively, r=.338, r=.360, p< .01), parental criticism (respectively, r=.180, r=.254, p< .01) and doubts about actions (respectively, r=.312, r=.189, p< .01). An unexpected result was the positive association with personal standards dimension (respectively, r=.178, p< .05; r=.204, p< .01).
Conclusions
The Portuguese version of FMPS showed good reliability and internal consistency. The perfectionism personality trait is associated with mood states.
To investigate in non-depressed perinatal women, whichBeck Depression Inventory-II (BDI-II) and Postpartum Postpartum DepressionScreening Scale (PDSS) scores and proportions of symptomatic items significantlydiffer through the perinatal period.
Methods
273 women were assessed with the Diagnostic Interviewfor Genetic Studies, BDI-II and the PDSS at the third trimester of pregnancy/T0(mean age =29.42±7.159 years; mean weeks gestation=32.6±3.61),three/T1, six/T2 and twelve/T3 months postpartum.
Results
Significantlyhigher scores in T0 than in T1/T2/T3 and in T1 than in T2/T3 were found for: Total PDSS, Sleeping-Eating Disturbances, Emotional Liability, Total BDI-II andits dimension Somatic-Anxiety. Only T0 and T1/T2 didnot significantly differ in Anxiety/Insecurity, Mental Confusion, and Loss of Self. In Guilty/Shame only T1 was significantly higher than T3. Suicidalthoughts were significantly higher in T0 than T1 and lower in T1 than T2/T3.
Theproportions of symptomatic items systematically and significantly decreased fromT0 to T3 in changes of sleep, loss of interest in sex, feeling overwhelmed. Significantlyhigher symptomatic proportions in T0 than in all post-partum moments were foundfor: loss of energy, irritability, fatigue, changes in appetite, crying, indecisiveness and worthlessness (these last three also higher in T1 than inT3). Agitation was significantly higherin T1 than in T0. All the cognitive-affective symptoms from BDI-II and PDSSdid not differ.
Conclusion
From pregnancy to the twelfth month postpartum the depressivesymptomatology, particularly somatic-affective symptoms, significantlydecreased. However even for the women who are not clinically depressed, theperinatal period requires considerable psychological adjustment.
Factors associated with postpartum/PPT anxiety have been insufficiently investigated.
Objective
To identify correlates of PPT anxiety.
Methods
201 3-months postpartum women completed the Portuguese versions of Postpartum Depression Screening Scale (PDSS), Beck Depression Inventory/BDI-II, Profile of Mood States, Difficult Infant Temperament Questionnaire/DITQ, Multidimensional Perfectionism Scale and questions on sociodemographic variables, Lifetime history of insomnia/LTHD, Lifetime history of depressive symptomatology/LTHDS, Current insomnia, Health perception/HP, Stress perception/SP, Perceived social support/PSS, Quality of life/QOL, Health problem/complication postpartum, Sensibility to hormonal fluctuations, Type of delivery and Type of feeding. Postpartum anxiety was measured with the Anxiety/Insecurity (AI) subscale of the PDSS.
Results
AI significantly correlated with LTHDS (rS=.32), LHI (rS=.18), Current insomnia (rS=.32), BDI-II (r=.76), SP (rS=.38), PSS (rS=.25), Perceived QOL (rS=.37), Health perception (rS=.29), Health problem in the postpartum (rS=.26), Negative Affect/NA (r=.66), Positive Affect/PA (r=.58), Conditional Acceptance/CA (r=.29) and DIT (r=.38) (all p< .01). Mean comparisons revealed that women with vs. without LHDS, with vs. without LTHI, good sleepers vs. with insomnia syndrome, high vs. low SP, low vs. high PSS, bad/very bad vs. good/very good QOL, bad/very bad vs. good/very good HP, high (< M+1DP) vs. low (>M-1DP) DIT, CA, NA and low vs. high PA had significantly higher mean scores in AI (all p< .01). Linear regression model composed of all correlated variables explained 53.7% of AI variance and showed that NA, PA and DIT are significant (p< .05) predictors of AI.
Conclusion
Our findings are in accordance with previous research and contribute to the progress on this topic.
Postpartum depressive symptomatology is highly prevalent and has negative impact in the entire family.
Objective
To identify correlates of postpartum depressive symptomatology.
Methods
201 3-months postpartum women completed the Portuguese versions of Postpartum Depression Screening Scale/PDSS, Profile of Mood States, Difficult Infant Temperament Questionnaire/DITQ, Multidimensional Perfectionism Scale and questions on sociodemographic variables (marital status, work status, educational level, parity), Lifetime history of insomnia/LTHD, Lifetime history of depressive symptomatology /LTHDS, Current insomnia, Sleep needs, Health perception/HP, Stress perception/SP, Perceived social support/PSS, Quality of life/QOL, Health problem/complication postpartum, Sensibility to hormonal fluctuations, Type of delivery and Type of feeding.
Results
Total PDSS significantly correlated with LTHDS (rs=.35), LHI (rs=.22), Current insomnia (rs=.37), SP (rs=39), PSS (rs=.25), Perceived QOL (rs=.31), Health perception (rs=.28), Health problem or complication in the postpartum (rs=.16), Negative Affect/NA (r=.59), Positive Affect/PA (r=-.67), Conditional Acceptance/CA(r=.29) and DIT (r=.40) (all p< .01). Mean comparisons revealed that women with vs. without LHDS, with vs. without LTHI, good sleepers vs. with insomnia syndrome, high vs. low SP, bad/very bad vs. good/very good QOL, bad/very bad vs. good very good HP, high (< M+1DP) vs. low (>M-1DP) DIT, CA, NA and low vs. high PA had significantly higher mean scores in AI (all p< .01). Linear regression model composed of all correlated variables explained 53.9% of depressive symptomatology variance and showed that NA, PA, DIT and HP are significant (p< .05) predictors of AI.
Conclusion
These results are in line with previous findings and contribute to the progress on this topic.
We wanted to explore the validity of measuring the tendency to worry and to overthink, in the Portuguese context. 714 medical students completed the following measures: Worry and Overthinking (two items each) “I worry a lot”, “The people around me consider that I worry a lot”, “I think a lot over things”, “The people around me consider that I think a lot over things”; Eysenck Personality Inventory (EPI) Neuroticism and Extroversion (NE-EPI/E-EPI); Arousal Predisposition Scale (Arousability); Revised NEO Personality Inventory (NEO-PI-R); Neuroticism facets Anxiety, Angry, Depression, Impulsiveness and Vulnerability; Profile of Mood States Positive and Negative Affect (POMS-PA/POMS-NA).
Worry and Overthinking were correlated (p < .001). Temporal stability was high (Worry p < .01; Overthinking p < .01; Worry+Overthinking p < .01). The 4 items factor structure yielded a single factor (a = .836). A factor analysis of these items with EPI items showed that they loaded highly (>.50) on the NE-EPI.
Worry and Overthinking were positively correlated with negative traits: NE-EPI, Arousability, POMS-NA, Neuroticism-NEO-PI-R (all p < .001) and with NEO-PI-R-N facets: all p values < .001, with the exception of Impulsiveness (p < .05). They were negatively correlated with positive traits: E-EPI and POMS-PA (all p < .001).
Based on Worry and Overthinking means and SD and considering frequencies five groups were formed: High worry/overthinking; High worry/low-medium overthinking; Medium worry/overthinking; Low worry/medium-high overthinking; High worry/overthinking. Groups mean comparisons significantly differ in positive and negative traits (means increased/decreased, respectively, from group 1 to 5). We provide preliminary evidence for the usefulness of this measure in this population.