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We describe system verification tests and early science results from the pulsar processor (PTUSE) developed for the newly commissioned 64-dish SARAO MeerKAT radio telescope in South Africa. MeerKAT is a high-gain (
${\sim}2.8\,\mbox{K Jy}^{-1}$
) low-system temperature (
${\sim}18\,\mbox{K at }20\,\mbox{cm}$
) radio array that currently operates at 580–1 670 MHz and can produce tied-array beams suitable for pulsar observations. This paper presents results from the MeerTime Large Survey Project and commissioning tests with PTUSE. Highlights include observations of the double pulsar
$\mbox{J}0737{-}3039\mbox{A}$
, pulse profiles from 34 millisecond pulsars (MSPs) from a single 2.5-h observation of the Globular cluster Terzan 5, the rotation measure of Ter5O, a 420-sigma giant pulse from the Large Magellanic Cloud pulsar PSR
$\mbox{J}0540{-}6919$
, and nulling identified in the slow pulsar PSR J0633–2015. One of the key design specifications for MeerKAT was absolute timing errors of less than 5 ns using their novel precise time system. Our timing of two bright MSPs confirm that MeerKAT delivers exceptional timing. PSR
$\mbox{J}2241{-}5236$
exhibits a jitter limit of
$<4\,\mbox{ns h}^{-1}$
whilst timing of PSR
$\mbox{J}1909{-}3744$
over almost 11 months yields an rms residual of 66 ns with only 4 min integrations. Our results confirm that the MeerKAT is an exceptional pulsar telescope. The array can be split into four separate sub-arrays to time over 1 000 pulsars per day and the future deployment of S-band (1 750–3 500 MHz) receivers will further enhance its capabilities.
Levels of serotonin in the body are regulated by the serotonin transporters (SERT), which are predominantly located on the presynaptic terminals of serotonin-containing neurons. Alterations in the density of SERT have been implicated in the pathophysiology of many neuropsychiatric disorders.
Aim
To evaluate 123-I mZIENT (2(S)-[(S)-2b-carbomethoxy-3b-[3′-((Z)-2-iodoethenyl)phenyl]nortropane), a novel radiopharmaceutical for imaging SERT. The bio-distribution of the radiopharmaceutical in humans was investigated and dosimetry performed.
Methods
The study includes three healthy volunteers and three patients receiving SSRIs. Whole body images obtained on a gamma camera at 10 minutes, 1, 2, 3, 6, 24 and 48 hours post administration. Dosimetry was performed. ROIs were drawn over the brain, heart, kidneys, liver, lungs, salivary glands, spleen, thyroid and intestines. Blood was sampled at 5, 15, & 30 minutes and 1, 2, 3, 6, 24 and 48 hours post administration. Urine was collected at 1, 2, 3, 4, 6, 24 and 48 hours. Brain SPECT images were obtained using a neuroSPECT scanner at 4 hours, evaluated visually and analysed using ROI analysis.
Results
High quality SPECT images can be obtained after 100–150 MBq 123-ImZEINT. Regional brain uptake was observed in midbrain and basal ganglia in healthy volunteers, consistent with the known distribution of SERT. Biodistribution images demonstrated highest uptake in the lungs, brain, liver and intestines. The effective dose was within range of other commonly used ligands and is acceptable for clinical imaging.
Conclusion
123-ImZIENT is a promising agent for imaging SERT in humans with acceptable dosimetry.
The recession of mountain glaciers worldwide is increasing global sea level and, in many regions, human activities will have to adapt to changes in surface hydrology. Thus, it is important to provide up-to-date analyses of glacier change and the factors modulating their response to climate warming. Here we report changes in the extent of >120 glaciers on the Lyngen Peninsula, northern Norway, where glacier runoff is utilised for hydropower and where glacial lake outburst floods have occurred. Glaciers covered at least 114 km2 in 1953 and we compare this inventory with those from 1988, 2001 and a new one from 2014, and previously-dated Little Ice Age (LIA) limits. Results show a steady reduction in area (~0.3% a−1) between their LIA maximum (~1915) and 1988, consistent with increasing summer air temperatures, but recession paused between 1988 and 2001, coinciding with increased winter precipitation. Air temperatures increased 0.5°C per decade from the 1990s and the rate of recession accelerated to ~1% a−1 between 2001 and 2014 when glacier area totalled ~95.7 km2. Small glaciers (<0.05 km2) with low maximum elevations (<1400 m) experienced the largest percentage losses and, if warming continues, several glaciers may disappear within the next two decades.
No existing models of alcohol prevention concurrently adopt universal and selective approaches. This study aims to evaluate the first combined universal and selective approach to alcohol prevention.
Method
A total of 26 Australian schools with 2190 students (mean age: 13.3 years) were randomized to receive: universal prevention (Climate Schools); selective prevention (Preventure); combined prevention (Climate Schools and Preventure; CAP); or health education as usual (control). Primary outcomes were alcohol use, binge drinking and alcohol-related harms at 6, 12 and 24 months.
Results
Climate, Preventure and CAP students demonstrated significantly lower growth in their likelihood to drink and binge drink, relative to controls over 24 months. Preventure students displayed significantly lower growth in their likelihood to experience alcohol harms, relative to controls. While adolescents in both the CAP and Climate groups demonstrated slower growth in drinking compared with adolescents in the control group over the 2-year study period, CAP adolescents demonstrated faster growth in drinking compared with Climate adolescents.
Conclusions
Findings support universal, selective and combined approaches to alcohol prevention. Particularly novel are the findings of no advantage of the combined approach over universal or selective prevention alone.
Most empirical studies into the covariance structure of psychopathology have been confined to adults. This work is not developmentally informed as the meaning, age-of-onset, persistence and expression of disorders differ across the lifespan. This study investigates the underlying structure of adolescent psychopathology and associations between the psychopathological dimensions and sex and personality risk profiles for substance misuse and mental health problems.
Method
This study analyzed data from 2175 adolescents aged 13.3 years. Five dimensional models were tested using confirmatory factor analysis and the external validity was examined using a multiple-indicators multiple-causes model.
Results
A modified bifactor model, with three correlated specific factors (internalizing, externalizing, thought disorder) and one general psychopathology factor, provided the best fit to the data. Females reported higher mean levels of internalizing, and males reported higher mean levels of externalizing. No significant sex differences emerged in liability to thought disorder or general psychopathology. Liability to internalizing, externalizing, thought disorder and general psychopathology was characterized by a number of differences in personality profiles.
Conclusions
This study is the first to identify a bifactor model including a specific thought disorder factor. The findings highlight the utility of transdiagnostic treatment approaches and the importance of restructuring psychopathology in an empirically based manner.
This article proposes an assessment of the ingestion doses potentially received by people
living in the Japanese areas most severely affected by the radioactive deposits due to the
Fukushima nuclear accident. The assessment distinguishes two consecutive periods: the
first 2 months (March 15th to May 15th 2011) and the rest of the year 2011, according to
the two main foodstuff contamination periods identified (Renaud et al.,
2013). On the basis of the worst-case hypothesis that can reasonably be made, the
estimated doses are much lower than they might have been in other circumstances, on
account of generally moderate levels of contamination for most foods, early evacuation of
the most severely affected areas and the consumption bans ordered by the Japanese
authorities. Thus, a single ingestion of 100 g of leafy vegetables in the early days by a
one-year-old child living in non-evacuated localities near Iitate and Kawamata could have
led to an equivalent dose to the thyroid of about 25 mSv; and to a thyroid dose of about
140 mSv for the rather unrealistic scenario of a daily consumption. Because of the rapid
decrease in the contamination of vegetables and a much weaker contamination of other
crops, and thanks to measures taken by the authorities (prohibition of consumption, use of
certain fodder, etc.), the ingestion doses potentially received during the remainder of
the year 2011 are estimated to be below 1 mSv. In the event that sales limits would have
been ignored, only repeated consumption of mushrooms would have led to doses above that
level. Even with the worst-case hypotheses, the doses potentially caused by ingestion are
much lower than those resulting from outdoor exposure to radioactive deposits:
approximately several millisieverts in a year for the population living in the
non-evacuated localities near Iitate and Kawamata.
During and after the Fukushima accident, the IRSN collected and interpreted the results
of radiological measurements performed on foodstuffs of terrestrial origin published by
Japan's Ministry of Health between mid-March 2011 and July 2012. Analysis of the findings
shows that the accident's date, livestock-rearing practices and the deposits'
characteristics had a decisive influence. The fact that radioactive fallout occurred very
early in the growing and breeding season largely explains the moderate contamination of
most foodstuffs of terrestrial origin, notably in the areas with the largest deposits. In
the case of dairy products and meat, feeding imported fodder to livestock in stables, a
common practice in Japan, compounded the calendar effect. Measurements published in Japan
have also borne out the particular sensitivity of mushrooms, including cultivated species,
and game.
The PULSE@Parkes project has been designed to monitor the rotation of radio pulsars over time spans of days to years. The observations are obtained using the Parkes 64-m and 12-m radio telescopes by Australian and international high school students. These students learn the basis of radio astronomy and undertake small projects with their observations. The data are fully calibrated and obtained with the state-of-the-art pulsar hardware available at Parkes. The final data sets are archived and are currently being used to carry out studies of 1) pulsar glitches, 2) timing noise, 3) pulse profile stability over long time scales and 4) the extreme nulling phenomenon. The data are also included in other projects such as gamma-ray observatory support and for the Parkes Pulsar Timing Array project. In this paper we describe the current status of the project and present the first scientific results from the Parkes 12-m radio telescope. We emphasise that this project offers a straightforward means to enthuse high school students and the general public about radio astronomy while obtaining scientifically valuable data sets.
The first direct detection of gravitational waves may be made through observations of pulsars. The principal aim of pulsar timing-array projects being carried out worldwide is to detect ultra-low frequency gravitational waves (f ∼ 10−9–10−8 Hz). Such waves are expected to be caused by coalescing supermassive binary black holes in the cores of merged galaxies. It is also possible that a detectable signal could have been produced in the inflationary era or by cosmic strings. In this paper, we review the current status of the Parkes Pulsar Timing Array project (the only such project in the Southern hemisphere) and compare the pulsar timing technique with other forms of gravitational-wave detection such as ground- and space-based interferometer systems.
A ‘pulsar timing array’ (PTA), in which observations of a large sample of pulsars spread across the celestial sphere are combined, allows investigation of ‘global’ phenomena such as a background of gravitational waves or instabilities in atomic timescales that produce correlated timing residuals in the pulsars of the array. The Parkes Pulsar Timing Array (PPTA) is an implementation of the PTA concept based on observations with the Parkes 64-m radio telescope. A sample of 20 ms pulsars is being observed at three radio-frequency bands, 50 cm (~700 MHz), 20 cm (~1400 MHz), and 10 cm (~3100 MHz), with observations at intervals of two to three weeks. Regular observations commenced in early 2005. This paper describes the systems used for the PPTA observations and data processing, including calibration and timing analysis. The strategy behind the choice of pulsars, observing parameters, and analysis methods is discussed. Results are presented for PPTA data in the three bands taken between 2005 March and 2011 March. For 10 of the 20 pulsars, rms timing residuals are less than 1 μs for the best band after fitting for pulse frequency and its first time derivative. Significant ‘red’ timing noise is detected in about half of the sample. We discuss the implications of these results on future projects including the International Pulsar Timing Array and a PTA based on the Square Kilometre Array. We also present an ‘extended PPTA’ data set that combines PPTA data with earlier Parkes timing data for these pulsars.
We report here on two years of timing of 168 pulsars using the Parkes radio telescope. The vast majority of these pulsars have spin-down luminosities in excess of 1034 erg s−1 and are prime target candidates to be detected in gamma-rays by the Fermi Gamma-Ray Space Telescope. We provide the ephemerides for the ten pulsars being timed at Parkes which have been detected by Fermi in its first year of operation. These ephemerides, in conjunction with the publicly available photonlist, can be used to generate gamma-ray profiles from the Fermi archive. We will make the ephemerides of any pulsars of interest available to the community upon request. In addition to the timing ephemerides, we present the parameters for 14 glitches which have occurred in 13 pulsars, seven of which have no previously known glitch history.The Parkes timing programme, in conjunction with Fermi observations, is expected to continue for at least the next four years.
In 2011 the IRSN conducted several assessments of atmospheric
radioactive releases due to the Fukushima Daiichi NPP accident (March
11, 2011) and of their impact on Japan’s terrestrial environment.
They were based on the IRSN’s emergency management tools and on
the abundant information and technical data gradually published
in Japan. According to these assessments, the main release phase
lasted from March 12 to 25, 2011 and impacted Japanese land in two
events, the first on 15 and 16 March, in which the main radioactive
deposits were formed, and the second from March 20 to 23, which
was less significant. The highest amounts of radioactive deposits were
found in an area extending upwards of several tens of kilometers
northwest of the plant. Lower amounts were discontinuously scattered
in an area extending up to over 250 km away. Initially composed
mainly of short-lived radionuclides, the deposits’ activity sharply
decreased in the subsequent weeks. Since the summer of 2011, cesium-134
and cesium-137 have become the residual deposits’ main components.
According to IRSN estimates, in the absence of protection, the doses
due to exposure to the radioactive plume during the atmospheric
release phase may have been potentially higher for people who remained
in coastal areas up to several tens of kilometers north and south
of the damaged plant. Thereafter, people living up to 50 km northwest
of the plant, outside the 20-km emergency evacuation zone, were potentially
most vulnerable to residual radioactive deposits over time.
Radio pulsars in relativistic binary systems are unique tools to study the curved space-time around massive compact objects. The discovery of a pulsar closely orbiting the super-massive black hole at the centre of our Galaxy, Sgr A⋆, would provide a superb test-bed for gravitational physics. To date, the absence of any radio pulsar discoveries within a few arc minutes of Sgr A⋆ has been explained by one principal factor: extreme scattering of radio waves caused by inhomogeneities in the ionized component of the interstellar medium in the central 100 pc around Sgr A⋆. Scattering, which causes temporal broadening of pulses, can only be mitigated by observing at higher frequencies. Here we describe recent searches of the Galactic centre region performed at a frequency of 18.95 GHz with the Effelsberg radio telescope.
The accident at the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) in March 2011 led to
an unprecedented direct input of artificial radioactivity into the marine environment. The
Institute for Radioprotection and Nuclear Safety was requested by the French authorities
to investigate the radioecological impact of this input, in particular the potential
contamination of products of marine origin used for human consumption. This article
describes the close link between the responses provided and the availability of the data,
as well as their nature and ability to meet the requirements of expert investigation.
These responses were needed: (i) to evaluate the inputs of radionuclides into the marine
environment, (ii) to understand their dispersion in seawater, and (iii) to estimate their
transfer to the biota and sediments. Three phases can be distinguished which characterise
these processes during the accident and post-accident periods. The first phase corresponds
to an emergency phase during which no measurements were available on samples from the
marine environment. It involved the formulation of hypotheses based solely on the
expertise of the Institute for Radioprotection and Nuclear Safety. The second phase
started when the Japanese authorities provided measurements of the concentrations of
radionuclides in seawater. Although these data were not yet adapted to addressing the
problems of radioecology, the scenarios could then be refined and the estimates developed
in more detail. During the third phase, the accumulation of data over the course of time
made it possible to study the phenomena in an appropriate way. The chronology of the
events shows that it is essential to have (i) significant measurements of concentration
from samples collected in the various matrices of the marine environment, regularly
updated and sufficiently well-documented, (ii) samples of seawater collected at the
earliest opportunity as close as possible to the damaged site to characterise the source
term, and (iii) a numerical tool allowing rapid modelling of the dispersion of
radionuclides in seawater, as well as their transfer to sediments and the biota,
ultimately for the purpose of estimating the dose to humans.
Strongly radiative shocks are characterized by an ionization front induced by the shock
wave. The role played together by opacity and geometry is critical for the physics of
these shock waves. Moreover, radiation is an obvious way of probing these shock waves,
either by self-emission or by probe absorption. These aspects will be illustrated by
recent experimental results obtained at the iodine PALS (Prague Asterix Laser System)
facility.
For many years, our group has been investigating the VUV spectroscopy and photochemistry
of molecules of astrophysical (Jochims et al. 2006a,b; Leach et al. 2008; Schwell et al. 2012) and prebiotic interest (Schwell et al. 2006). Polyynes and cyano-polyynes that are abundant in
the interstellar medium (ISM) and in planetary atmospheres, have been investigated too
(e.g. Fray et al. 2010). An aerosol source for reactive and thermo-labile compounds has been
developed (Gaie-Levrel et al. 2011)
to perform gas-phase measurements. These are necessary to measure intrinsic molecular
properties and to compare to quantum chemical calculations. Besides measuring absolute
absorption and photoionization cross sections, dissociative channels and their involved
excited states are identified for a number of molecules of interstellar interest.
Branching ratios of the respective elementary photoreactions are determined in order to
understand and model the photochemistry occurring in the ISM. Some very recent results on
the dissociative photoionization of methylformate (MF), glycolaldehyde (GA), dimethylether
(DIM), aminoacetonitrile (AAC) and cyanoacetylene (CA), are presented here.
Development of metallic glasses is hindered by the difficulties in manufacturing bulk parts. We report on the preparation of glassy alloys using the spark plasma sintering of gas atomized powders. The Zr57Cu20Al10Ni8Ti5 alloy processed has a high glass forming ability. Densification is obtained at the glass transition temperature (390 °C) under high pressure (≈500 MPa). Systematic study of the effect of powder particles size and sintering time is performed through structural and thermal analyses. Local and partial devitrification of the amorphous alloy is detected, resulting from local temperature overshoots. From these analyses, an approach of the spark plasma sintering mechanism of metallic glasses is proposed.