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Despite of the evidence of high psychopathological disorders in patients with ATSCI, few data are available on their psychiatric morbidity prior to the injury.
Identify psychiatric morbidity pre-post ATSCI in a sample of patients admitted in the Spinal Injuries Unit of the Vall d’ Hebron University Hospital in Barcelona (Spain).
Material and methods
54 patients with ATSCI patients were admitted between 1st. October 2009 and 1st. October 2010. SPSS (version 16.1) was used to analyze the data.
Seventy-six percent of the inpatients with ATSCI (41 cases) were evaluated by the psychiatrist and constitute the study sample. Twenty-seven (66%) were male and 14 (33%) female. The average age of the sample was 41 years with younger males (p < 0.05).
Reasons for ATSCI in males were traffic accident (26%), accidental falls and sports accidents (both 18.5%). In women were suicidal attempt by precipitation, fall accident (28.6% both) and traffic accident (21.4%).
41% of men versus 14% of women had a history of substance misuse (p < 0.01) while 64% of women versus the 14.8% of males had a prior psychiatric disorder (p < 0.01). 72.5% of men with ATSCI caused by traffic accident had used substances prior to the accident, those association was not found for women.
91% of patients underwent psychopharmacological intervention.
ATSCI patients exhibit high psychiatric morbidity and require specialized assessment. The high incidence of substance use associated with road traffic injuries suggests the need to identify risk groups in order to establish effective preventive measures.
Background. Orthotopic heart transplantation (OHT) is a major surgical intervention inducing distress and anxiety. Psychiatric evaluation of organ transplant candidates is now routinely proposed. This study purposed to assess the psychological evolution in patients having received psychological and/or psychiatric assistance before and during 1–6 postoperative months. Methods. Twenty-two consecutive transplant candidates were psychically evaluated as part of the preoperative protocol. In the waiting period, 1 and 6 months after OHT, they were asked to fill out the following questionnaires: the General Health Questionnaire, the Spielberger’s State-Trait Anxiety Inventory, the Beck Depression Inventory, the Perceived Social Support Scale, the Toronto Alexithymia Scale and the Personal Reaction Inventory. Results. A DSM-IV Axis I diagnosis was found in nine patients (41%); four patients (18%) presented with an Axis II diagnosis. One month after OHT, scores of depression, anxiety and general health significantly improved, while scores of social support, alexithymia and social desirability did not differ. In the sixth postoperative month, all psychological scores remained stable. Conclusions. A high prevalence of preoperative psychopathology was reported in 22 candidates who received OHT. Surgical intervention obviously improved the quality of life after cardiac transplantation. If the impact of psychological and/or psychiatric aid remains difficult to appraise, these results emphasize the positive impact of surgery on psychological status and the appropriateness of the psychosomatician’s social support intervention on patients facing the transplant process.
Livestock farming is an essential activity in many rural areas, where it contributes to the maintenance of soil fertility and farmland biodiversity, as well as to a set of social public goods including food security, rural vitality and culture. However, livestock sustainability assessments tend to focus primarily on environmental and economic dimensions; therefore, these valuations might be limited because they do not consider the complete set of associated goods and services (GS). Hence, a need exists to recognise the multiple contributions provided by livestock to human well-being and society. The objective of this study was to analyse the provision of multiple GS derived from livestock across regions in France and empirically demonstrate sets of GS that repeatedly appeared together. We designated these multiple GS provided by livestock as contributions to productive, environmental, rural vitality and cultural benefits that human populations derive directly or indirectly from livestock agroecosystems. First, we combined expert knowledge with results of a literature review to define a bundle of GS provided by livestock. We then described indicators that quantified each good or service and screened national databases to determine the availability of supporting data. Finally, we assessed the GS and their relationships (synergies or trade-offs) on a nation-wide gradient in France at the department level (Nomenclature of Territorial Units for Statistics 3). Four main categories of GS were considered: provisioning (e.g. food quantity and quality), environmental quality (e.g. biodiversity, landscape heterogeneity, water quality), rural vitality (e.g. employment, rural dynamism) and culture (e.g. gastronomy and landscape heritage). Four major types of GS bundles were identified, which suggested strong contrasts among French rural areas in terms of the nature of the GS that occurred together and their levels of provision. GS bundles in France had a non-random spatial distribution. This study represents an initial step towards developing a methodology to consider GS bundles provided by livestock. Nonetheless, further research is needed to understand socio-economic, environmental, political and geographic determinants of the composition of GS bundles.
Irradiation of reactor pressure vessel (RPV) steels causes the formation of nanoscale microstructural features (termed radiation damage), which affect the mechanical properties of the vessel. A key tool for characterizing these nanoscale features is atom probe tomography (APT), due to its high spatial resolution and the ability to identify different chemical species in three dimensions. Microstructural observations using APT can underpin development of a mechanistic understanding of defect formation. However, with atom probe analyses there are currently multiple methods for analyzing the data. This can result in inconsistencies between results obtained from different researchers and unnecessary scatter when combining data from multiple sources. This makes interpretation of results more complex and calibration of radiation damage models challenging. In this work simulations of a range of different microstructures are used to directly compare different cluster analysis algorithms and identify their strengths and weaknesses.
Poor effortful control is a key temperamental factor underlying behavioral problems. The bidirectional association of child effortful control with both positive parenting and negative discipline was examined from ages approximately 3 to 13–14 years, involving five time points, and using data from parents and children in the Oregon Youth Study—Three Generational Study (N = 318 children from 150 families). Based on a dynamic developmental systems approach, it was hypothesized that there would be concurrent associations between parenting and child effortful control and bidirectional effects across time from each aspect of parenting to effortful control and from effortful control to each aspect of parenting. It was also hypothesized that associations would be more robust in early childhood, from ages 3 to 7 years, and would diminish as indicated by significantly weaker effects at the older ages, 11–12 to 13–14 years. Longitudinal feedback or mediated effects were also tested. The findings supported (a) stability in each construct over multiple developmental periods; (b) concurrent associations, which were significantly weaker at the older ages; (c) bidirectional effects, consistent with the interpretation that at younger ages children's effortful control influenced parenting, whereas at older child ages, parenting influenced effortful control; and (d) a transactional effect, such that maternal parenting in late childhood was a mechanism explaining children's development of effortful control from middle childhood to early adolescence.
This paper presents an innovative design of an Ultra Wide-Band (UWB) impulse radiation source. The transmitting system is composed of an UWB antenna with an integrated optoelectronic generator, which is able to feed the system with appropriate waveforms, a pulsed high voltage source, and an optical command system. The radiation source is the elementary part of a forthcoming short-range UWB Radar with autonomous scanning capability. In this paper, we present in detail the necessary subsystems required to design the elementary radiation source. Measurements have been performed to validate the proposed radiation source and this offers a mathematical method of calculation to trace back to the radiated field at 1 m.
The Teff (effective temperature) scale for M dwarfs is very uncertain. One method which can be used to establish this scale is to compare observed spectra to synthetic ones derived from appropriate model atmospheres. With this method the adequacy of the model atmosphere is of great importance and simple models can give incorrect results. Alternatively if the Teff scale is known with some accuracy then this comparison is a good test of the adequacy of the models. We have computed some new and preliminary model atmospheres for late type dwarfs which accurately treat the line opacity with the opacity sampling technique and employ laboratory values for the transition strengths of molecular bands. With the above two considerations in mind we compare the fluxes of these models to observed fluxes of late K and early M dwarfs. This preliminary analysis indicates a discrepancy with the currently accepted Teff scale for early M dwarfs with the models suggesting values some 200 K hotter.
Breed risk status assessment methods are key components of country-based early warning and response systems. In this study, a multi-indicator method was developed to assess the risk status of livestock populations. Six indicators were used: (i) the current number of breeding females; (ii) the change in the number of breeding females over the last 5 years or generations (depending on the species); (iii) percentage of cross-breeding; (iv) effective population size; (v) breeders organization and technical support; and (vi) socio-economic context. To make these indicators comparable, observed values were converted into scores on a six-point scale (from 0 = no threat to 5 = maximum threat); a specific conversion method was used for each indicator. For each breed, the different scores were analysed graphically and an overall score was calculated by averaging the six separate indicator scores. This approach was applied to 178 French local breeds, belonging to ten different species: horse, donkey, goat, pig, chicken, turkey, goose and Pekin duck. A large percentage of local breeds were found to be at risk to be lost for farming, although the results were species dependent. All local equine and pig breeds, as well as almost all local poultry breeds appeared to be endangered. About 80 percent of local goat and cattle breeds, and half local sheep breeds were also found to be at risk. The usefulness of this method with regards to conservation strategies and public policy is discussed.
Stars in low-mass dwarf galaxies show a larger range in their chemical properties than those in the Milky Way halo. The slower star formation efficiency make dwarf galaxies ideal systems for testing nucleosynthetic yields. Not only are alpha-poor stars found at lower metallicities, and a higher fraction of carbon-enhanced stars, but we are also finding stars in dwarf galaxies that appear to be iron-rich. These are compared with yields from a variety of supernova predictions.
Expose is a multi-user instrument for astrobiological and astrochemical experiments in space. Installed at the outer surface of the International Space Station, it enables investigators to study the impact of the open space environment on biological and biochemical test samples. Two Expose missions have been completed so far, designated as Expose-E (Rabbow et al. 2012) and Expose-R (Rabbow et al. this issue). One of the space-unique environmental factors offered by Expose is full-spectrum, ultraviolet (UV)-rich electromagnetic radiation from the Sun. This paper describes and analyses how on Expose-R, access of the test samples to Solar radiation degraded during space exposure in an unpredicted way. Several windows in front of the Sun-exposed test samples acquired a brown shade, resulting in a reduced transparency in visible light, UV and vacuum UV (VUV). Post-flight investigations revealed the discolouration to be caused by a homogenous film of cross-linked organic polymers at the inside of the windows. The chemical signature varied per sample carrier. No such films were found on windows from sealed, pressurized compartments, or on windows that had been kept out of the Sun. This suggests that volatile compounds originating from the interior of the Expose facility were cross-linked and photo-fixed by Solar irradiation at the rear side of the windows. The origin of the volatiles was not fully identified; most probably there was a variety of sources involved including the biological test samples, adhesives, plastics and printed circuit boards. The outer surface of the windows (pointing into space) was chemically impacted as well, with a probable effect on the transparency in VUV. The reported analysis of the window contamination on Expose-R is expected to help the interpretation of the scientific results and offers possibilities to mitigate this problem on future missions – in particular Expose-R2, the direct successor of Expose-R.
The study of the evolution of organic matter subjected to space conditions, and more specifically to Solar photons in the vacuum ultraviolet range (120–200 nm) has been undertaken in low-Earth orbit since the 1990s, and implemented on various space platforms. This paper describes a photochemistry experiment called AMINO, conducted during 22 months between 2009 and 2011 on the EXPOSE-R ESA facility, outside the International Space Station. Samples with relevance to astrobiology (connected to comets, carbonaceous meteorites and micrometeorites, the atmosphere of Titan and RNA world hypothesis) have been selected and exposed to space environment. They have been analysed after return to the Earth. This paper is not discussing the results of the experiment, but rather gives a general overview of the project, the details of the hardware used, its configuration and recent developments to enable long-duration exposure of gaseous samples in tight closed cells enabling for the first time to derive quantitative results from gaseous phase samples exposed in space.
Interventional cardiologists (ICs) are repeatedly exposed to scattered ionising radiation
during the cardiac procedures they perform, and radiation protection is an important issue
for these medical professionals. The use of radiation protection tools is particularly
relevant to this population. SISERI (Système d’Information de la Surveillance de
l’Exposition aux Rayonnement Ionisants, that is, an information system for monitoring
exposure to ionising radiation) is a register that stores personal dosimeter readings for
dosimetric monitoring. This paper, based on data for a sample of French ICs from the
O’CLOC epidemiological study, aims to provide an overview of the use of radiation
protection equipment and dosimetric devices reported by ICs in a specific questionnaire as
well as the dosimetric information found in the SISERI database for this population.
Material and Methods − Annual information on interventional cardiology activity for the
period from 01/01/2005 to 31/12/2009 was collected in an occupational questionnaire. ICs
were asked to report the frequency in which they used individual dosimeter and radiation
protection tools (lead apron, thyroid shield, eyewear or face shield, ceiling-suspended
shield) as follows: never (0% of the time), occasionally (<50%), regularly (>50%), always (100%). We retrieved their
medical radiation exposure information (monitored status and monthly effective doses) from
the SISERI database for the period 2005−2009. Results – Information for 132 ICs (mean age in
2005 = 46 ± 7 years) was
available. All ICs reported routine use of lead aprons, in contrast to their occasional
use of lead eyewear or face shields. During the study period, 49% reported systematic use
of personal dosimeters, and 21% more regular use. On the other hand, 18% never used a
dosimeter during this period. The SISTERI database included 92% of our population, 73% of
whom had complete annual dose monitoring in SISERI (corresponding to at least 11 months
per year of recorded data). Conclusion − ICs must improve their regular use of
radiation protection tools and systematic use of personal dosimeters. The SISERI database
is an appropriate tool for flagging those medical professionals exposed to ionising
radiation. Better awareness of the importance of radiation protection rules in this
population, in particular, systematic dosimeter use, remains an important issue.
The nature of the intermetallic layer which forms on the steel surface during immersion
in typical galvanizing baths for galvannealed (GA) sheets production has been investigated
on two commercial Titanium-stabilized Interstitial-Free (Ti-IF) steel substrates
galvanized in baths with different Al contents. Results from this study show that in both
cases the inhibition layer is biphasic and composed of a very thin Al-rich phase layer,
identified as Fe2Al5Znx, and a thicker Zn-rich phase layer
on top of it, identified as δ. Experimental results also show that the
Fe2Al5Znx phase layer becomes discontinuous
when decreasing the bath Al content. Discussions about the mechanisms of formation and the
final microstructure of this inhibiting layer are also tackled in this paper by means of
the Al-Fe-Zn ternary phase diagram at 460 °C and assumptions to justify any deviation from
thermodynamic equilibrium are as well proposed.
It has long been assumed that radiocarbon (Δ14C) content of dissolved inorganic carbon (DIC) is equal to that of particulate organic carbon (POC) in surface seawater; however, little research has been conducted to explicitly test this assumption. Here, we report Δ14C measurements of surface POC samples and compare them with contemporaneous DIC Δ14C measurements from the northeast Pacific Ocean (Hwang et al. 2004; Druffel et al. 2010). Samples were collected from surface waters at Station M off California between 1995 and 2004. The POC Δ14C values decreased 3.2% per year from 1995 to 2004, similar to the decline observed in the DIC Δ14C values during the same period. Overall, our results show no statistical difference between POC and DIC Δ14C—consistent with the assumption that DIC and POC Δ14C values can generally be considered equivalent. However, significant variability was observed for POC Δ14C values during several fall/summer events, where POC Δ14C signatures were lower than DIC Δ14C values. An evaluation of 2 sample pretreatments also suggests that non-homogenized POC samples deviated less from average POC Δ14C values and more closely matched the DIC Δ14C average for the time series. The presence of seasonal POC/DIC Δ14C disagreements, combined with sample processing effects, suggest that infrequent contributions of allochthonous, older carbon may have originated from deeper in the water column, especially during periods when upwelling in this area was prominent.
To evaluate the clinical course and pathological characteristics of basaloid head and neck squamous cell carcinoma.
Retrospective study of 18 cases of basaloid head and neck squamous cell carcinoma. Epidemiological, clinical and histological data were analysed and the Kaplan–Meier test used to estimate survival rates.
The majority of lesions were at an advanced stage. These lesions were primarily localised in the larynx, hypopharynx and oropharynx. Routine pre-therapeutic assessment of squamous cell carcinoma was performed. Pathological diagnosis was difficult, although immunostaining was extremely useful. Positive staining for KL1, MNF 116 and 34βE12 and negative immunostaining for chromogranin and synaptophysin were also important factors in obtaining a definitive diagnosis. In the majority of cases, treatment involved surgery and radiotherapy. The five-year survival rate was 5 per cent.
Basaloid squamous cell carcinoma is an uncommon head and neck lesion, with a challenging histological diagnosis. These lesions must be carefully monitored due to their aggressive course, and require multimodality treatment.
On 13 November 2009, the authorities of Flemish Brabant, Belgium, received an alert concerning a potential outbreak of Shigella sonnei at a public institution. A study was conducted to assess the extent, discover the source and to implement further measures. We performed a matched case-control study to test an association between shigellosis and canteen-food consumption. Water samples and food handlers' faecal samples were tested. The reference laboratory characterized the retrospectively collected Shigella specimens. We found 52 cases distributed over space (25/35 departments) and time (2 months). We found a matched odds ratio of 3·84 (95% confidence interval 1·02–14·44) for canteen-food consumption. A food handler had travelled to Morocco shortly before detection of the first laboratory-confirmed case. Water samples and food handlers' faecal samples tested negative for Shigella. Confirmed cases presented PFGE profiles, highly similar to archived isolates from Morocco. Foodborne transmission associated with the canteen was strongly suspected.
The ecosystem-based approach to fisheries management and, more specifically,
the European Marine Strategy Framework Directive require the assessment of
the state and dynamics of an ecosystem in order to determine suitable
management strategies. This paper takes an analytical approach to assess the
state of the Bay of Biscay ecosystem in the early 1990s, chosen as a period
of reference because key monitoring data series have been collected since
then. To assess the state of the ecosystem, the pressures exerted by six
broad categories of human activities were examined. A literature review of
the ecosystem components was made and a component tree was tailored
according to data availability. Data rich components were subdivided into
subcomponents for their assessment while data poor components were assessed
at an aggregated level. The component tree of the ecosystem comprised six
main branches, four of which further divided into sub-components. In total,
assessments were carried out at the level of 19 components. For four of
these (fished species, sensitive fish species, marine mammals and turtles)
the overall assessments were made combining the status of individual
species. Impact from human activities were categorised as (i) “widespread”
over the whole Bay of Biscay or “local” and (ii) “possible” when they
could be logically expected or “documented” when they were reported in the
literature. Fishing appeared to be the only activity exerting widespread
documented impacts on several ecosystem components. Terrestrial activities
had some possible and documented widespread impacts. With the exception of
marine transport impacting seabirds at the regional scale through oil
pollution, other activities had only local impacts, mostly nearshore. The
reference state in the early 1990s, suggests that continuation of monitoring
of vertebrates as well as estuarine and coastal habitats must be central to
the monitoring programme and management strategies to be set in the context
of the Marine Strategy Framework Directive. Additional monitoring is also
required for benthos, substrate and micro-organisms.