We present the construction of a continuous-time stochastic process which has moments that satisfy an exact scaling relation, including odd-order moments. It is based on a natural extension of the multifractal random walk construction described in Bacry and Muzy (2003). This allows us to propose a continuous-time model for the price of a financial asset that reflects most major stylized facts observed on real data, including asymmetry and multifractal scaling.

Highly Focused Ion Beams (FIB) are used to produce in one step large quantities of solid state nanopores drilled in thin dielectric films with high reproducibility and well controlled morphologies. We explore both the production of nanopores of various diameters and study their applicability to different biological molecules such as DNA, or folded and unfolded proteins, and then we compare their transport properties. We also report on the translocation of Fibronectin which an original experiment made possible is using the methodology described in this article.

Here we propose to detail an innovative FIB instrumental approach and processing methodologies we have developed for sub-10 nm nanopore fabrication. The main advantage of our method is first to allow direct fabrication of nanopores in relatively large quantities with an excellent reproducibility. Second our approach offers the possibility to further process or functionalize the vicinity of each pore on the same scale keeping the required deep sub-10 nm scale positioning and patterning accuracy. We will summarise the optimisation efforts we have conducted aiming at fabricating thin (10-100 nm thick) and high quality dielectric films to be used as a template for the nanopore fabrication, and at performing efficient and controlled FIB nanoengraving of such a delicate media. Finally, we will describe the method we have developed for integrating these “single nanopore devices” in electrophoresis experiments and our preliminary measurements.

The temporal organization of the late babbling of a French child during the pivotal period between babbling and the production of meaningful utterances is studied. Two points are analysed: the segmental timing in terms of syllabic durations and the durations of sequences according to their intonational contours. Articulation rate in late babbling is fairly rapid and stable and does not vary with length of sequences. However, at the end of the period studied, longer durations are found for bi- and tri-syllabic sequences. This lengthening can be seen to reflect changes in the child's target programming and the constraints on co-articulation that it implies. Additional changes occur also as a function of intonational contours.

The late babbling productions of a French child are analysed and compared with a similar study of English-speaking children. English-speaking and French children are shown to share such universal phonetic preferences as cluster reduction, final devoicing, etc. However, there are also noticeable differences which may be ascribed to corresponding differences in the target language. Thus a selective, language-specific, phonetic acquisition has been taking place during the babbling stage. A comparison of the phonetic repertoires of French, English, Thai and the late babbling corpus confirmed the close similarity between the latter and French. This study reinforces the view that babbling is relevant to the study of linguistic performance.