We investigated and synthesized different orientation and substituted group of the thieno-pyridine framework organo-iridium complexes (PO-01, PO-02, PO-03). These materials exhibited yellow light. Fabrication of these emissive phosphorescent dopants with the device configuration of ITO/ NPB/ CBP: Ir-complex (4–6%) /BCP/Alq3/LiF/Al showed the EL emitting peak from 532nm to 564nm. The electroluminescent efficiencies of the devices were from 9.62 lm/W to 30.41 lm/W and maximum brightness was all above 7000 cd/m2. We demonstrated high-efficiency, high-brightness and saturated yellow Ir-complex phosphorescent materials for OLED.