To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Parkinson's disease (PD) is associated with cognitive and emotional disturbances, whose response to dopamine therapy is either absent or, occasionally, deleterious to the patient. By measuring cerebral blood flow (CBF), first with positron emission tomography (PET) and now with functional magnetic resonance imaging (fMRI), researchers have mapped the neurobiological substrates of cognitive and behavioral symptoms in PD. Basal ganglia processing is based on the anatomy of parallel cortico-striatal loops, each of which has a functional role. Dopaminergic overmedication may lead to cognitive impairment via an action on the relatively preserved mesocortical or mesolimbic systems. The overmedication hypothesis has been rekindled recently with the description of disorders of motivation and impulse control in PD. fMRI provides evidence that dopamine may contribute to impulse control disorders (ICDs) in PD via its role as an energizing or activating agent that assigns incentive value to stimuli and actions.
Email your librarian or administrator to recommend adding this to your organisation's collection.