Personal digital assistants (PDA) and handheld global positioning systems (GPS) have become increasingly important in cotton production but little is known about their use. This research analyzed the adoption of PDA/handheld GPS devices in cotton production. A younger farmer who used a computer in farm management and had a positive perception of Extension had a greater likelihood of adopting the devices. In addition, farmers who used complementary remote sensing, plant mapping, and grid soil sampling information were more likely to use PDA/handheld GPS devices. Finally, the COTMAN in-field decision support program from Extension also positively impacted adoption.