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17 results

  • 1 - Introduction

  • Edited by Katherine Blouin, University of Toronto
  • Book:
    The Nile Delta
    Published online:
    15 February 2024
    Print publication:
    22 February 2024, pp 1-67

  • Summary

    This volume is not a textbook or a handbook. It does not survey the history of the Nile Delta in a linear, streamlined and homogeneous way. Neither is it a volume that pretends to account for all places, peoples and stories from or tied to the region. Rather than aiming for exhaustiveness or completeness, the contributors offer over a dozen ‘stories made of true events’ about the history of Egypt’s ‘Northern Land’. Taken together, the following chapters illuminate the historical significance and complex webs of the region’s shifting landscapes and imperial histories over the course of over five millennia.

  • 2 - Call Me by My Names

  • Edited by Katherine Blouin, University of Toronto
  • Book:
    The Nile Delta
    Published online:
    15 February 2024
    Print publication:
    22 February 2024, pp 68-104

  • Summary

    The ancient-to-modern Nile Delta has been consistently conceptualised as a coherent, distinctive region, and toponymy is one of the manifestations of this space-making process. In that regard, available evidence, which ranges from the Old Kingdom to modern times and covers a variety of scripts and languages, testifies to two partly overlapping yet simultaneously distinctive takes on the region. One adopts an insider’s, fluvial and south–north vantage point; the other, an outsider’s, maritime and north–south one. The etymology, diachronic endurance and translation of the toponyms (t3-)mḥw and Δέλτα indicate a tension between the unswerving appeal of the indigenous understanding of the Delta as a place and the long-lasting, far-reaching posterity of the ancient Greek tradition beyond and within Egypt. This chapter analyses available literary and documentary evidence of the name(s) given to what we now commonly call the Nile Delta, from Antiquity to the modern period. I propose that we consider these place names as both manifestations and vectors of stories, and reflect on their contribution to our understanding of human pluri-millennial entanglements with this territory. I first discuss the two, Egyptian and Greek, names associated with the region, before focusing on the polysignificance of the apex region.

The Nile Delta
  • Histories from Antiquity to the Modern Period
  • Edited by Katherine Blouin
  • Published online:
    15 February 2024
    Print publication:
    22 February 2024
  • This is the first volume on the history of the Nile Delta to cover the c.7000 years from the Predynastic period to the twentieth century. It offers a multidisciplinary approach engaging with varied aspects of the region's long, complex, yet still underappreciated history. Readers will learn of the history of settlement, agriculture and the management of water resources at different periods and in different places, as well as the naming and mapping of the Delta and the roles played by tourism and archaeology. The wide range of backgrounds of the contributors and the broad panoply of methodological and conceptual practices deployed enable new spaces to be opened up for conversations and cross-fertilization across disciplinary and chronological boundaries. The result is a potent tribute to the historical significance of this region and the instrumental role it has played in the shaping of past, present and future Afro-Eurasian worlds.

  • Applications of a cell culture system for studying the interaction of Anaplasma marginale with tick cells

  • Edmour F. Blouin, José de la Fuente, Jose C. Garcia-Garcia, John R. Sauer, Jeremiah T. Saliki, Katherine M. Kocan
  • Journal:
    Animal Health Research Reviews / Volume 3 / Issue 2 / December 2002
    Published online by Cambridge University Press:
    09 March 2007, pp. 57-68

  • A cell culture system for the tick-borne rickettsia Anaplasma marginale offers new opportunities for research on this economically important pathogen of cattle. A. marginale multiplies in membrane-bound inclusions in host cells. Whereas erythrocytes appear to be the only site of infection in cattle, A. marginale undergoes a complex developmental cycle in ticks and transmission occurs via the salivary glands during feeding. We recently developed a cell culture system for A. marginale using a cell line derived from embryos of Ixodes scapularis. Here we review the use of this cell culture system for studying the interaction of A. marginale with tick cells. Several assays were developed using the A. marginale/tick cell system. An adhesion assay was developed for the identification of proteins required by A. marginale for adhesion to tick cells. The effect of antibodies against selected major surface proteins in inhibiting A. marginale infection was tested in an assay that allowed further confirmation of the role of surface proteins in the infection of tick cells. A drug screening assay for A. marginale was developed and provides a method of initial drug selection without the use of cattle. The culture system was used to test for enhancing effects of tick saliva and saliva components on A. marginale infection. The tick cell culture system has proved to be a good model for studying A. marginale–tick interactions. Information gained from these studies may be applicable to other closely related tick-borne pathogens that have been propagated in the same tick cell line.

  • Evolution and function of tandem repeats in the major surface protein 1a of the ehrlichial pathogen Anaplasma marginale

  • José de la Fuente, Jose C. Garcia-Garcia, Edmour F. Blouin, Sergio D. Rodríguez, Migel A. García, Katherine M. Kocan
  • Journal:
    Animal Health Research Reviews / Volume 2 / Issue 2 / December 2001
    Published online by Cambridge University Press:
    28 February 2007, pp. 163-174

  • The major surface protein (MSP) 1a of the ehrlichial cattle pathogen Anaplasma marginale, encoded by the single-copy gene msp1α, has been shown to have a neutralization-sensitive epitope and to be an adhesin for bovine erythrocytes and tick cells. msp1α has been found to be a stable genetic marker for the identification of geographic isolates of A. marginale throughout development in acutely and persistently infected cattle and in ticks. The molecular weight of MSP1a varies among geographic isolates of A. marginale because of a varying number of tandemly repeated peptides of 28–29 amino acids. Variation in the sequence of the tandem repeats occurs within and among isolates, and may have resulted from evolutionary pressures exerted by ligand–receptor and host–parasite interactions. These repeated sequences include markers for tick transmissibility that may be important in the identification of ehrlichial pathogens because they may influence control strategies and the design of subunit vaccines.