A number of studies suggest that individual cognitive-behavioural therapy (CBT) is beneficial to patients suffering from Chronic Fatigue Syndrome (CFS). This study investigated the effectiveness of group CBT in reducing fatigue and distress in five outpatients with a diagnosis of CFS throughout therapy and at 3-month follow-up. The nature of the group, treatment outcomes and benefits of this approach are outlined. Group CBT was acceptable to participants and led to improvements in fatigue as well as cognitive functioning.