In this paper, longitudinal and lateral-directional aerodynamic characterisation of the Cropped Delta Reflex Wing (CDRW) configuration–based unmanned aerial vehicle is carried out by means of full-scale static wind-tunnel tests followed by full-scale flight testing. A predecided set of longitudinal and lateral/directional manoeuvres is performed to acquire the respective flight data, using a dedicated onboard flight data acquisition system. The compatibility of the acquired dynamics is quantified, in terms of scale factors and biases of the measured variables, using Kinematic consistency check. Maximum likelihood (ML), least squares and newly emerging neural Gauss–Newton (NGN) methods were implemented for a wing-alone delta configuration, mainly to capture the dynamic derivatives for both longitudinal and lateral directional cases. Estimated damping and weak dynamic derivatives, which are in general challenging to capture for a wing alone configuration, are consistent using ML and NGN methods. Validation of the estimated parameters with aerodynamic model is performed by proof-of-match exercise and are presented therein.

Background: Buprenorphine/naloxone (bup/nal) is a partial opioid agonist/antagonist and recommended first line treatment for opioid use disorder (OUD). Emergency departments (EDs) are a key point of contact with the healthcare system for patients living with OUD. Aim Statement: We implemented a multi-disciplinary quality improvement project to screen patients for OUD, initiate bup/nal for eligible individuals, and provide rapid next business day walk-in referrals to addiction clinics in the community. Measures & Design: From May to September 2018, our team worked with three ED sites and three addiction clinics to pilot the program. Implementation involved alignment with regulatory requirements, physician education, coordination with pharmacy to ensure in-ED medication access, and nurse education. The project is supported by a full-time project manager, data analyst, operations leaders, physician champions, provincial pharmacy, and the Emergency Strategic Clinical Network leadership team. For our pilot, our evaluation objective was to determine the degree to which our initiation and referral pathway was being utilized. We used administrative data to track the number of patients given bup/nal in ED, their demographics and whether they continued to fill bup/nal prescriptions 30 days after their ED visit. Addiction clinics reported both the number of patients referred to them and the number of patients attending their referral. Evaluation/Results: Administrative data shows 568 opioid-related visits to ED pilot sites during the pilot phase. Bup/nal was given to 60 unique patients in the ED during 66 unique visits. There were 32 (53%) male patients and 28 (47%) female patients. Median patient age was 34 (range: 21 to 79). ED visits where bup/nal was given had a median length of stay of 6 hours 57 minutes (IQR: 6 hours 20 minutes) and Canadian Triage Acuity Scores as follows: Level 1 – 1 (2%), Level 2 – 21 (32%), Level 3 – 32 (48%), Level 4 – 11 (17%), Level 5 – 1 (2%). 51 (77%) of these visits led to discharge. 24 (47%) discharged patients given bup/nal in ED continued to fill bup/nal prescriptions 30 days after their index ED visit. EDs also referred 37 patients with OUD to the 3 community clinics, and 16 of those individuals (43%) attended their first follow-up appointment. Discussion/Impact: Our pilot project demonstrates that with dedicated resources and broad institutional support, ED patients with OUD can be appropriately initiated on bup/nal and referred to community care.

The detection of a neutron star merger by the Advanced Laser Interferometer Gravitational-Wave Observatory and Advanced Virgo gravitational wave detectors, and the subsequent detection of an electromagnetic counterpart have opened a new era of transient astronomy. With upgrades to the Advanced Laser Interferometer Gravitational-Wave Observatory and Advanced Virgo detectors and new detectors coming online in Japan and India, neutron star mergers will be detected at a higher rate in the future, starting with the O3 observing run which will begin in early 2019. The detection of electromagnetic emission from these mergers provides vital information about merger parameters and allows independent measurement of the Hubble constant. The Australian Square Kilometre Array Pathfinder is expected to become fully operational in early 2019, and its 30 deg2 field of view will enable us to rapidly survey large areas of sky. In this work we explore prospects for detecting both prompt and long-term radio emission from neutron star mergers with Australian Square Kilometre Array Pathfinder and determine an observing strategy that optimises the use of telescope time. We investigate different strategies to tile the sky with telescope pointings in order to detect radio counterparts with limited observing time, using 475 simulated gravitational wave events. Our results show a significant improvement in observing efficiency when compared with a naïve strategy of covering the entire localisation above some confidence threshold, even when achieving the same total probability covered.

The problem of unsteady boundary layer flow of a nanofluid over a stretching surface is studied. Heat transfer due to melting is analyzed. Using a similarity transformation the governing coupled nonlinear partial differential equations of the model are reduced to a system of nonlinear ordinary differential equations, and then solved numerically by a Runge-Kutta method with a shooting technique. Dual solutions are observed numerically and their characteristics are analyzed. The effects of the pertinent parameters such as the acceleration parameter, the Brownian motion parameter, the thermophoresis parameter, the Prandtl number and the Lewis number on the velocity, temperature and concentration fields are discussed. Also the effects of these parameters on the skin friction coefficient, the Nusselt number and the Sherwood number are analyzed through graphs. It is observed that the melting phenomenon has a significant effect on the flow, heat and mass transfer characteristics.

Crystal structure analysis of a pyrazole carboxylic acid derivative, 5-(trifluoromethyl)-1-phenyl-1H-pyrazole-4-carboxylic acid (1) has been carried out from laboratory powder X-ray diffraction data. The crystal packing in the pyrazole carboxylic acid derivative exhibits an interplay of strong O–H…O, C–H…N and C–H…F hydrogen bonds to generate a three-dimensional molecular packing via the formation of R22(8) and R22(9) rings. Molecular electrostatic potential calculations indicated that carbonyl oxygen, pyrazole nitrogen and fluorine atoms to be the strongest acceptors. The relative contribution of different interactions to the Hirshfeld surface of pyrazole carboxylic acid and a few related structures retrieved from CSD indicates that H…H, N…H and O…H interactions can account for almost 70% of the Hirsfeld surface area in these compounds.

Dust vortices with a void at the centre are reported in this paper. The role of the spatial variation of the plasma potential in the rotation of dust particles is studied in a parallel plate glow discharge plasma. Probe measurements reveal the existence of a local potential minimum in the region of formation of the dust vortex. The minimum in the potential well attracts positively charged ions, while it repels the negatively charged dust particles. Dust rotation is caused by the interplay of the two oppositely directed ion drag and Coulomb forces. The balance between these two forces is found to play a major role in the radial confinement of the dust particles above the cathode surface. Evolution of the dust vortex is studied by increasing the discharge current from 15 to 20 mA. The local minimum of the potential profile is found to coincide with the location of the dust vortex for both values of discharge currents. Additionally, it is found that the size of the dust vortex as well as the void at the centre increases with the discharge current.

In this paper, a Gaussian process regression (GPR)-based novel method is proposed for non-linear aerodynamic modelling of the aircraft using flight data. This data-driven regression approach uses the kernel-based probabilistic model to predict the non-linearity. The efficacy of this method is examined and validated by estimating force and moment coefficients using research aircraft flight data. Estimated coefficients of aerodynamic force and moment using GPR method are compared with the estimated coefficients using maximum-likelihood estimation (MLE) method. Estimated coefficients from the GPR method are statistically analysed and found to be at par with estimated coefficients from MLE, which is popularly used as a conventional method. GPR approach does not require to solve the complex equations of motion. GPR further can be directed for the generalised applications in the area of aeroelasticity, load estimation, and optimisation.

The current research paper describes the lateral-directional parameter estimation from flight data of a miniature Unmanned Aerial Vehicle (UAV) using Maximum Likelihood (ML), and Neural-Gauss-Newton (NGN) methods. An unmanned configuration with a cropped delta planform and thin rectangular cross-section has been designed, fabricated and instrumented. Exhaustive full-scale wind-tunnel tests were performed on the UAV to extract the form of aerodynamic model that has to be postulated a priori for parameter estimation. Rigorous flight tests have been performed to acquire the flight data for several prescribed manoeuvres. Four sets of compatible flight data have been used to carry out parameter estimation using classical ML and neural-network-based NGN methods. It is observed that the estimated parameters are consistent and the lower values of the Cramer-Rao bound for the corresponding estimates have shown significant confidence in the obtained parameters. Furthermore, to validate the aerodynamic model used and to enhance the confidence in the estimated parameters, a proof of match exercise has been carried out.

Artificial Neural Network based Nonlinear Autoregressive Model is designed to reconstruct and predict Forbush Decrease (FD) Data obtained from Izmiran, Russia. Result indicates that the model seems adequate for short term prediction of the FD data.

A new species, Gentiana arunii D.Maity, S.K.Dey, J.Ghosh & Midday, from alpine pasture in Sikkim Himalaya is described and illustrated, and placed in Gentiana section Chondrophyllae Bunge. The new species is compared morphologically with two related taxa, Gentiana glabriuscula T.N.Ho and Gentiana pluviarum W.W.Sm. subsp. subtilis (Harry Sm.) T.N.Ho.

While sharply different rotational temperature for the lower and higher rotational states of H2 have been observed in astrophysical situations, studies on heavier molecules are less encountered. We report here results of plasma spectroscopic studies on the nitrogen system where the FNS bands (0,0) and (0,1) show much distinctive ‘two-temperature’ phenomena, the departure from the high rotational temperature part (840 ± 50°K and 920 ± 30°K respectively) being perceptible at N' (N' + 1) ≅ 160. the experimental system is an electron beam sustained magnetoplasma at 5 × 10−3 torr, with kTe ≅ 1.5 eV and ne ≅ 4 × 1010 cm−3 obtained from in situ measurements of plasma parameters. Relative excitation-deexcitation rates of the N2 + B2Σu + rotational states and also in relation to those of H2 are discussed.

The reactions between O and N atoms and certain interstellar molecules (H2S, NH3, H2CO, CH3 OH, C2 H5 OH) are studied using the dynamicalflowing after glow method. It is found that NH and OH radicals are formed which can be used as a diagnostic probe to differentiate between interstellar shocked and heated regions.

the pathways for the formation and destruction processes of ring molecules in interstellar medium have been proposed and their abundances have been calculated under steady state conditions and calculated abundances are of the order of 10−12 n(H), where n(H) is the abundance of hydrogen. Also their detection proposal has been presented.

Heterodyne spectroscopy at 11 μm combines high spectral resolution (λ/Δ λ ~106), high spatial resolution (< 1 arcsec at 3 m telescopes) and high penetration depth. Therefore, it seems promising to use it also for the investigation of bright circumstellar atmospheres.

IRAS has provided infrared maps of a large number of galaxies. However the size of IRAS survey detectors is quite large (∼5′ in the cross-scan direction) and there is a need for improving the resolution of these maps. In order to understand the spatial structure of galaxies, we have generated high resolution maps of 18 large galaxies by deconvolving the IRAS pointed observations from survey detectors as well as from Chopped Photometric Channel (CPC) using Maximum Entropy Method (MEM).

IRAS has provided infrared maps of a large number of galaxies. However the size of IRAS survey detectors is quite large (∼5′ in the cross-scan direction) and there is a need for improving the resolution of these maps. In order to understand the spatial structure of galaxies, we have generated high resolution maps of 18 large galaxies by deconvolving the IRAS pointed observations from survey detectors as well as from Chopped Photometric Channel (CPC) using Maximum Entropy Method (MEM).

Measurements of local plasma parameters in dusty plasma are crucial for understanding the physics issues related to such systems. The Langmuir probe, a small electrode immersed in the plasma, provides such measurements. However, designing of a Langmuir probe system in a dusty plasma environment demands special consideration. First, the probe has to be miniaturized enough so that its perturbation on the ambient dust structure is minimal. At the same time, the probe dimensions must be such that a well-defined theory exists for interpretation of its characteristics. The associated instrumentation must also support the measurement of current collected by the probe with high signal to noise ratio. The most important consideration, of course, comes from the fact that the probes are prone to dust contamination, as the dust particles tend to stick to the probe surface and alter the current collecting area in unpredictable ways. This article describes the design and operation of a Langmuir probe system that resolves these challenging issues in dusty plasma. In doing so, first, different theories that are used to interpret the probe characteristics in collisionless as well as in collisional regimes are discussed, with special emphasis on application. The critical issues associated with the current–voltage characteristics of Langmuir probe obtained in different operating regimes are discussed. Then, an algorithm for processing these characteristics efficiently in presence of ion-neutral collisions in the probe sheath is presented.

Most nutritional studies on the development of children focus on mother–infant interactions. Maternal nutrition is critically involved in the growth and development of the fetus, but what about the father? The aim is to investigate the effects of paternal methyl-group donor intake (methionine, folate, betaine, choline) on paternal and offspring global DNA (hydroxy)methylation, offspring IGF2 DMR DNA methylation, and birth weight. Questionnaires, 7-day estimated dietary records, whole blood samples, and anthropometric measurements from 74 fathers were obtained. A total of 51 cord blood samples were collected and birth weight was obtained. DNA methylation status was measured using liquid chromatography-tandem mass spectrometry (global DNA (hydroxy)methylation) and pyrosequencing (IGF2 DMR methylation). Paternal betaine intake was positively associated with paternal global DNA hydroxymethylation (0.028% per 100 mg betaine increase, 95% CI: 0.003, 0.053, P=0.03) and cord blood global DNA methylation (0.679% per 100 mg betaine increase, 95% CI: 0.057, 1.302, P=0.03). Paternal methionine intake was positively associated with CpG1 (0.336% per 100 mg methionine increase, 95% CI: 0.103, 0.569, P=0.006), and mean CpG (0.201% per 100 mg methionine increase, 95% CI: 0.001, 0.402, P=0.049) methylation of the IGF2 DMR in cord blood. Further, a negative association between birth weight/birth weight-for-gestational age z-score and paternal betaine/methionine intake was found. In addition, a positive association between choline and birth weight/birth weight-for-gestational age z-score was also observed. Our data indicate a potential impact of paternal methyl-group donor intake on paternal global DNA hydroxymethylation, offspring global and IGF2 DMR DNA methylation, and prenatal growth.