To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure email@example.com
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Six new species of Piezocerini (Coleoptera: Cerambycidae: Cerambycinae) are described: Alienosternus sanjacintero, Hemilissa bifasciata, Hemilissa erikae, Hemilissa claudiae, and Migorybia santossilvai from Colombia and Alienosternus wappesi from Bolivia. The genus Alienosternus Martins, 1976 is recorded for the first time for Colombia and Bolivia, and the genus Migorybia Martins, 1985 is recorded for the first time for Colombia. The geographical distribution of three species is expanded, and keys to species of Alienosternus and Hemilissa Pascoe, 1858 are provided.
In many developing countries, national legislative seats are considered less valuable than (subnational) executive positions. Even then, ambitious politicians may seek a legislative seat either (a) as a window of opportunity for jumping to an executive office; or (b) as a consolation prize when no better option is available. Using a regression discontinuity design adapted to a pr setting, we examine these possibilities in the Argentine Chamber of Deputies between 1983 and 2011. In line with the consolation prize story, we find that marginal candidates from the Peronist party—which controls most provincial governorships—are more likely to be renominated and serve an additional term in the legislature, but not necessarily to jump to an executive office. The effect is stronger in small provinces.
In Canada, recreational use of cannabis was legalized in October 2018. This policy change along with recent publications evaluating the efficacy of cannabis for the medical treatment of epilepsy and media awareness about its use have increased the public interest about this agent. The Canadian League Against Epilepsy Medical Therapeutics Committee, along with a multidisciplinary group of experts and Canadian Epilepsy Alliance representatives, has developed a position statement about the use of medical cannabis for epilepsy. This article addresses the current Canadian legal framework, recent publications about its efficacy and safety profile, and our understanding of the clinical issues that should be considered when contemplating cannabis use for medical purposes.
At the international level, there is an increasing recognition that victims can claim reparations from those convicted for crimes that caused harm on victims. The International Criminal Court contains the first reparations regime among international criminal tribunals. This chapter seeks to examine the human right to reparations as enjoyed by victims of international crimes at the International Criminal Court and demonstrate the interaction between international human rights law and international criminal law at the reparations system of the International Criminal Court. Thus, this chapter has three sections. First, human rights clauses of the International Criminal Court’s reparations system are discussed. Second, the status and procedural rights of victims as reparations claimants at the International Criminal Court are examined. Third, how the International Criminal Court Chambers have used and adapted international human rights law to interpret and apply reparations provisions of the International Criminal Court instruments is analysed.
The Sierra de Pie de Palo, in the Argentinean Sierras Pampeanas (Andean foreland), consists of a Mesoproterozoic basement and an Ediacaran – upper Cambrian sedimentary cover that underwent folding, thrusting and metamorphism during the Ordovician Famatinian orogeny. Mafic rocks and granitoids of the easternmost Sierra de Pie de Palo provide information about the magmatic activity at the proto-Andean margin of Gondwana during late Cambrian – Early Ordovician time. Magmatic activity began in the Sierra de Pie de Palo as dykes, sills and small intrusions of tholeiitic gabbros between 490 and 470 Ma, before shortening and regional metamorphism. Variable mantle sources (Nd depleted mantle age, TDM between 1.7 and 1.3 Ga) were involved in the mafic magmatism. Nd-isotope signatures were probably inherited from a Mesoproterozoic subcontinental mantle. Mafic magmatism was coincident with collapse of a Cambrian carbonate-siliciclastic platform that extended along SW Gondwana, and was probably coeval with the beginning of subduction. After mafic magmatism, peraluminous granitoids were emplaced in the Sierra de Pie de Palo along ductile shear zones during a contractional tectonic phase, coeval with moderate to high P/T metamorphism, and with the Cordilleran-type magmatic arc that resulted from a flare-up at c. 470 Ma. Granitoids resulted mainly from partial melting of metasedimentary rocks, although some hybridization with juvenile magmas and/or rocks cannot be ruled out. The evidence shown here further implies that the Pie de Palo block was part of the continental upper plate during the Famatinian subduction, and not an exotic block that collided with the Gondwana margin.
This is a retrospective cohort study based on data from five nursing homes which aims to appraise how physical and cognitive characteristics of nursing home residents were associated with the use of restraints, and to provide information on their prevalence in Spain. The goal was to assess, in a visual way, the possible interactions between the nursing homes residents’ characteristics and their association with the use of restraints. Motivation, risk factors, characteristics of the residents analysed by validated rating systems that assess mobility, level of dependence, cognitive condition and nutritional status, and their association with the use of restraints, were described by means of linear and non-linear multivariate approaches in the form of self-organised maps. Findings showed that the prevalence of restraints was high when compared to other developed countries. The visual analysis reinforced the knowledge that a greater impairment was associated with the use of restraints and vice versa. However, the residents’ characteristics were not always associated with the use of restraints. Subjective factors seem to play a relevant role in decision-making, so it is important to assess risk factors continuously and determine the actual need for the use of restraints from an individual perspective by basing the criteria on specific objectives, and on consistent, reproducible and reliable methods. Initiatives to minimise these subjective factors should be promoted. Likewise, a clear definition of physical restraints should be offered at each centre. In addition, effective legislation that clearly states the need, alternatives and motivation for the use of restraints is needed.
To determine whether (-)-epicatechin (Epi) could decrease visceral adipose tissue and improve the metabolic profile of male offspring rats, after maternal obesity was induced by a high-fat diet (HFD).
Maternal obesity in albino Wistar rats was induced with a HFD, whereas male offspring were fed with chow diet throughout the study. Eight male offspring per group, from different litters, were randomly assigned to the experimental or to the control groups. In the experimental group, Epi was administered at a dose of 1 mg/kg of body weight to the male offspring twice daily for two weeks, beginning at postnatal day (PND).
Weight of visceral adipose tissue, adipocyte size, and several metabolic parameters.
Epi administration in the male offspring induced a significant decrease in the amount of visceral fat (11.61 g less, P < 0.05) and in the size of adipose cells (28% smaller, P < 0.01). Besides, Epi was able to decrease insulin, leptin, and Homeostasis Model Assessment -Insulin Resistance (HOMA-IR) (P < 0.05), as well as triglycerides, when the experimental group was compared to the untreated male offspring of obese rats (P < 0.01).
Epi administration can reverse the negative effects that maternal obesity has on the male offspring. This could be because Epi reduces the amount of visceral fat and improves metabolic profile.