Recent analyses use geometric morphometrics (GM), the quantitative study of shape and its variation, to examine aspects of the archaeological record. Our research builds on such applications to examine the organization of production by applying GM analysis to whole ceramic vessels from the Casas Grandes culture of northwest Mexico. We quantify variation in vessel shape and size and conclude that specialists made at least some of the Ramos and Babicora Polychromes, but that the other Casas Grandes ceramic types were generally made by nonspecialists. This bolsters arguments for Medio period (AD 1200 to 1450) specialized production above the household level but indicates that specialized production was limited to a subset of economically valuable goods. We further suggest some Ramos Polychrome was made by attached specialists associated with elites at Paquime, the religious center of the Medio period, whereas some Babicora Polychrome was made by independent specialists. The analysis contributes to three important anthropological topics: (1) the study of the Medio period Casas Grandes culture, and by extension the organization of production in mid-level hierarchically organized societies; (2) geometric morphometric analysis of archaeological collections; and (3) the Standardization Hypothesis and the relationship between artifact standardization and the organization of production.