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Over the past decade, the World Health Summit (WHS) has provided a global platform for policy-makers and decision-makers to interact with academics and practitioners on global health. Recently the WHS adopted health security into their agenda for transnational disease risks (eg, Ebola and antimicrobial resistance) that increasingly threaten multiple sectors. Global health engagement (GHE) focuses efforts across interdisciplinary and interorganizational lines to identify critical threats and provide rapid deployment of key resources at the right time for addressing health security risks. As a product of subject matter experts convening at the WHS, a special side-group has organically risen with leadership and coordination from the German Institute for Defense and Strategic Studies in support of GHE activities across governmental, academic, and industry partners. Through novel approaches and targeted methodology that maximize outcomes and streamline global health operational process, the Global Health Security Alliance (GloHSA) was born. This short conference report describes in more detail the GloHSA.
Previous research regarding anxiety as a predictor of future cognitive decline in older adults is limited and inconsistent. We examined the independent relationship between anxiety symptoms and subsequent cognitive decline.
Methods:
We included 2,818 community-dwelling older men (mean age = 76.1, SD ±5.3 years) who were followed on an average for 3.4 years. We assessed anxiety symptoms at baseline using the Goldberg Anxiety Scale (GAS; range = 0–9). We assessed cognitive function at baseline and at two subsequent visits using the Modified Mini-Mental State Examination (3MS; global cognition) and the Trails B test (executive function).
Results:
At baseline, there were 690 (24%) men with mild anxiety symptoms (GAS 1–4) and 226 (8%) men with moderate/severe symptoms (GAS 5–9). Men with anxiety symptoms were more likely to have depressed mood, poor sleep, more chronic medical conditions, and more impairment in activities of daily living compared to those with no anxiety symptoms. Compared to those with no anxiety symptoms at baseline, men with any anxiety symptoms were more likely to have substantial worsening in Trails B completion time (OR = 1.56, 95% CI 1.19, 2.05). The association was attenuated after adjusting for potential confounders, including depression and poor sleep, but remained significant (OR = 1.40, 95% CI 1.04, 1.88).
Conclusion:
In cognitively healthy older men, mild anxiety symptoms may potentially predict future decline in executive functioning. Anxiety is likely a manifestation of an underlying neurodegenerative process rather than a cause.
This book presents a wide range of new research on many aspects of naval strategy in the early modern and modern periods. Among the themes covered are the problems of naval manpower, the nature of naval leadership and naval officers, intelligence, naval training and education, and strategic thinking and planning. The book is notable for giving extensive consideration to navies other than those ofBritain, its empire and the United States. It explores a number of fascinating subjects including how financial difficulties frustrated the attempts by Louis XIV's ministers to build a strong navy; how the absence of centralised power in the Dutch Republic had important consequences for Dutch naval power; how Hitler's relationship with his admirals severely affected German naval strategy during the Second World War; and many more besides. The book is a Festschrift in honour of John B. Hattendorf, for more than thirty years Ernest J. King Professor of Maritime History at the US Naval War College and an influential figure in naval affairs worldwide.
N.A.M. Rodger is Senior Research Fellow at All Souls College, Oxford.
J. Ross Dancy is Assistant Professor of Military History at Sam Houston State University.
Benjamin Darnell is a D.Phil. candidate at New College, Oxford.
Evan Wilson is Caird Senior Research Fellow at the National Maritime Museum, Greenwich.
Contributors: Tim Benbow, Peter John Brobst, Jaap R. Bruijn, Olivier Chaline, J. Ross Dancy, Benjamin Darnell, James Goldrick, Agustín Guimerá, Paul Kennedy, Keizo Kitagawa, Roger Knight, Andrew D. Lambert, George C. Peden, Carla Rahn Phillips, Werner Rahn, Paul M. Ramsey, Duncan Redford, N.A.M. Rodger, Jakob Seerup, Matthew S. Seligmann, Geoffrey Till, Evan Wilson
The collective response of electrons in an ultrathin foil target irradiated by an ultraintense (
${\sim}6\times 10^{20}~\text{W}~\text{cm}^{-2}$
) laser pulse is investigated experimentally and via 3D particle-in-cell simulations. It is shown that if the target is sufficiently thin that the laser induces significant radiation pressure, but not thin enough to become relativistically transparent to the laser light, the resulting relativistic electron beam is elliptical, with the major axis of the ellipse directed along the laser polarization axis. When the target thickness is decreased such that it becomes relativistically transparent early in the interaction with the laser pulse, diffraction of the transmitted laser light occurs through a so called ‘relativistic plasma aperture’, inducing structure in the spatial-intensity profile of the beam of energetic electrons. It is shown that the electron beam profile can be modified by variation of the target thickness and degree of ellipticity in the laser polarization.
The rate of transportation, introduction, dissemination, and spread of nonnative species is increasing despite growing global awareness of the extent and impact of biological invasions. Effective policies are needed to prevent an increase in the significant negative environmental and economic impacts caused by invasive species. Here we explore this issue in the context of the history of invasion and subsequent regulation of cacti introduced to South Africa. We consider seven approaches to restricting trade by banning the following: (1) species already invasive in the region, (2) species invasive anywhere in the world, (3) species invasive anywhere in the world with a climate similar to the target region, (4) genera containing invasive species, (5) growth forms associated with invasiveness, (6) cacti with seed characteristics associated with invasiveness, and (7) the whole family. We evaluate each approach on the basis of the availability and complexity of information required for implementation, including the cost of the research needed to acquire such information, the likely numbers of false positives and false negatives, the likely degree of public acceptance, and the costs of implementation. Following a consultative process, we provide recommendations for how to regulate nonnative cacti in South Africa. The simplest option would be to ban all cacti, but available evidence suggests that most species pose negligible risk of becoming invasive, making this option unreasonable. The other extreme—reactively regulating species once they are invasive—would incur significant control costs, likely result in significant environmental and economic impacts, and limit management goals (e.g., eradication might be unfeasible). We recommended an intermediate option—the banning of all genera containing invasive species. This recommendation has been partly incorporated in South African regulations. Our study emphasizes the importance of scientific research, a legal framework, and participation of stakeholders in assessments. This approach builds awareness, trust, and support, and ensures that all interests are reflected in final regulations, making them easier to implement and enforce.
Malawi is under heavy pressure for land by an increasing human population, and there is little natural habitat left outside gazetted wildlife and forest reserves. Widespread collecting of birds in Malawi’s small protected rain forests by the National Museum of Malawi in conjunction with Western academic institutions has been taking place almost yearly since 2001 and has continued until at least 2011. The collection of specimens, although often a contentious issue, does have scientific value but should be undertaken in a limited way with careful evaluation of the populations from which birds are being taken. We consider that the numbers collected are likely to pose a threat to some bird populations in view of their isolation and the slow turn-over rates of breeding individuals. Collecting has been carried out in some of the same reserves two or three times within a few years. Examples are given of very small populations in Malawi and adjacent Mozambique where the slightest off-take would be very dangerous. Many species have been collected during their breeding season, which we find both wasteful and unethical. Several of the species collected occur in no more than one or two reserves today in Malawi and in such instances we recommend their complete protection. We are also concerned about the example presented to the local communities, reserve wardens and young conservation biologists by the off-take of hundreds of birds in official reserves which were primarily set up for the protection of wildlife.