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The rise of antiquarianism in late Elizabethan/early Jacobean England posed a threat to the common and traditional notion of continuity through time of British institutions and culture, including the transmission of historical texts. This threat was a major preoccupation for the poet Michael Drayton, and his response to it can be examined in his depictions of bards and druids in Poly Olbion. Conservatives in the historiographical debate put forth these ancient British poet/priests as an explanation for how ancient British history could have been transmitted through the centuries. But while Drayton in the Poly Olbion certainly uses bards and druids in a concerted attempt to imagine continuity, he reveals some latent suspicions of the truth - that ancient British culture was irretrievably lost.
Cell-implant adhesive strength is important for prostheses. In this paper, an investigation is described into the adhesion of bovine chondrocytes to Ti6Al4V-based substrates with different surface roughnesses and compositions. Cells were cultured for 2 or 5 days, to promote adhesion. The ease of cell removal was characterised, using both biochemical (trypsin) and mechanical (accelerated buoyancy and liquid flow) methods. Computational fluid dynamics (CFD) modelling has been used to estimate the shear forces applied to the cells by the liquid flow. A comparison is presented between the ease of cell detachment indicated using these methods, for the three surfaces investigated.
A patient with severe long-standing panic disorder who made a full recovery whilst pregnant, only to relapse during the postpartum period, is presented. Sex steroids may have a role in the aetiology and management of panic disorder. This is potentially an important area which requires further research.
We report three patients with striatonigral degeneration highlighting the correlation between magnetic resonance imaging (MRI) and the pathological changes. The “slit-like void signal” observed in the putamen is typical of striatonigral degeneration and can be used to assist diagnosis during life. Our histochemical studies support the concept that increased iron deposition in the putamen is responsible for this MRI picture.
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