Field studies were conducted at three locations to evaluate glyphosate-resistant (GR) cotton response, weed control, and cotton lint yields to two formulations of glyphosate (diammonium salt– glyphosate and isopropylamine salt–glyphosate) and trifloxysulfuron applied early postemergence (EPOST) alone or to tank mixtures of trifloxysulfuron with each glyphosate formulation, with and without a late postemergence-directed (LAYBY) treatment of prometryn plus MSMA. Trifloxysulfuron and both formulations of glyphosate controlled common lambsquarters and pitted morningglory. Both glyphosate formulations provided equivalent control of common lambsquarters, goosegrass, pitted morningglory, prickly sida, and smooth pigweed. Trifloxysulfuron controlled smooth pigweed better than either glyphosate formulation but did not control goosegrass or prickly sida. Prometryn plus MSMA LAYBY improved late-season control of common lambsquarters, goosegrass, large crabgrass, and pitted morningglory for all EPOST systems and improved late-season smooth pigweed control for EPOST systems that did not include trifloxysulfuron. Cotton injury was 2% or less from both glyphosate formulations, while trifloxysulfuron injured ‘Deltapine 5415RR’ 7 to 16% at two locations. At a third location, trifloxysulfuron injured ‘Paymaster 1218RR/BG’ 24%, and when applied in mixture with either glyphosate formulation, injury increased to at least 72%. Cotton injury was transient at the first two locations and was not visually apparent 3 to 5 wk later. Cotton yield at the third location was reduced. High cotton yields reflected high levels of weed control.

The goal of this brief review is to address the role of the ageing gut in the genesis of malnutrition in the elderly. We assess the burden of malnutrition in the elderly, exploring the role of comorbid conditions and neurohumoral changes that take place to contribute towards the process of anorexia associated with ageing. Following this, the review assesses physiological changes that occur in each part of the gastrointestinal (GI) tract and what implication they may have in clinical practice. In the oropharynx and the oesophagus, changes in swallowing and oesophageal motility associated with ageing can be demonstrated using physiological testing. However, in the absence of comorbid disease, they often have little, if any, clinical significance. In the stomach, reduced fundal compliance may contribute to early satiety; however, the primary change is hypochlorhydria, which may predispose to malabsorption or bacterial overgrowth further along the GI tract. Almost uniquely, the small bowel, particularly its absorptive function, is unaffected by age and we review the literature demonstrating this. In the colon, there is evidence of a prolonged transit time related to a reduction in both neurotransmitters and receptors. Although this may cause symptoms, this aspect is unlikely to contribute to malnutrition. In addition, we assess the potential changes in the gut microbiome and how this may interact with the immune system in the process of ‘inflamm-ageing’. We conclude by summarising the main changes and their impact for the clinician along with recommendations for future areas of research.

Smoking is closely linked to severe mental illness and has a major detrimental impact on individuals' lives. Despite this and the recent societal ‘de-normalisation’ of smoking, the historic ‘smoking culture’ still prevails within mental health settings. Change is urgently required to prevent a widening of existing health gaps.

The British dominated the world's submarine cable business over the second half of the nineteenth century, but they encountered significant challenges in the 1880s and 1890s—especially from James Scrymser, an upstart entrepreneur from New York. Scrymser exploited a strategic gap in the cable system in the Western Hemisphere and became locked in a confrontation along the west coast of South America with John Pender, the leading British cable magnate. Scrymser gained the upper hand in Chile by outmaneuvering Pender and used this victory to expand his operations with the telegraph network that linked South America, North America, and Europe.

There are few validated methods of measuring dietary fatty acid intake that are suitable for epidemiological research. The purpose of the present study was to develop and validate a food-frequency questionnaire (FFQ) developed to measure individual dietary fatty acid intakes against 7d weighed dietary records, in a sample of thirty-one healthy adult volunteers. The FFQ was based on a previously validated questionnaire (DIETQ; Tinuviel Software, Warrington, Ches., UK), adapted to include greater detail on those foods from which the majority of dietary fatty acids are obtained. The FFQ and weighed records were analysed using food nutrient data from McCance and Widdowson's Food Composition Tables, supplemented with a food fatty acid content database (Foodbase, London, UK). Results from the two dietary assessment methods were compared by correlation coefficients and limits of agreement. The mean intake of individual fatty acids tended to be lower when assessed by FFQ. Correlation coefficients comparing unadjusted individual fatty acid intakes assessed by FFQ and weighed records ranged from 0·29 for 18:1n−9 to 0·71 for 20:4n−6. Adjusting for energy intake tended to increase the correlation coefficients between saturated fatty acids and decrease those between unsaturated fatty acids. In conclusion, this food-frequency method provides reliable estimates of dietary intake of many individual fatty acids for use in epidemiological studies.

The aim of Working Group 5 is to develop and coordinate education and support networks for individuals and organizations undertaking or using assessment of health interventions and to identify needs in the field and assist in the establishment of new provisions.

While feed-forward mechanisms may be ubiquitous in biological systems that form the substrates of Pavlovian conditioning, the control system proposed by Domjan, Cusato & Villarreal seems too elaborate for Pavlovian conditioning of simple skeletal muscle responses. We discuss here how the known neural substrates of classical eyeblink conditioning can be described in feed-forward terms, but argue that the monitor/comparator part of the system is not necessary and perhaps could even be detrimental to simple, nonsocial forms of Pavlovian conditioning.

This paper investigates all aspects of the orthography of the Ormulum in relation to the phonology of the late twelfth-century south Lincolnshire dialect which Orm's spelling system was designed to reflect. We show that Orm's adaptations of what he found in existing orthographic systems provided a set of graphic symbols that was fully capable of representing phonological contrasts in the vocabulary of the dialect and which thus in many respects resembled the inventory that an analysis on phonemic principles might provide. However, Orm's system has more orthographic symbols than an analysis of distinctive oppositions in speech would have required. All of these additions are in some measure attributable to following precedent. In this aspect of his spelling system, as in his innovations, nearly all of which also have parallels within the English orthographic tradition, we discern a spelling reformer who, in due consideration of transparency of the system as perceived by the reader, took pains to depart as little as possible from the familiar.