In this article, we discuss strategies for resisting further encroachment on Indigenous existences by Settler societies and states – and as well multinational corporations and other elite organizations controlled by state powers and other elements of the imperial institutional network; and we focus on how Indigenous communities can regenerate themselves to resist the effects of the contemporary colonial assault and regenerate politically and culturally. We ask the fundamental question: how can we resist further dispossession and disconnection when the effects of colonial assaults on our own existences are so pronounced and still so present in the lives of all Indigenous peoples?