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Somatic severity of a self-poisoning episode varies widely between
To determine the correlates (psychiatric profiles, long-term outcome) of
mechanical ventilation used as a proxy to define somatic severity during
All patients who required mechanical ventilation were pair-matched with
ones who did not for age, gender and presence of psychiatric history. One
year after the self-poisoning episode, patients were interviewed using
the Hospital Anxiety and Depression Scale (HADS) and a quality-of-life
assessment questionnaire (Short-Form 12 Health Survey).
The ventilation group (n = 99) more frequently had mood
disorders and less frequently had adjustment disorders
(P = 0.007), with a higher depression score on the
HADS (P = 0.01) than those in the non-ventilation group
(n = 97). Survival curves showed lower survival in
the ventilation group (P = 0.03).
Requirement for mechanical ventilation following self-poisoning is
associated with a high prevalence of mood disorders and poor long-term
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