We use time-lapse photography, MODIS satellite imagery, ocean wave measurements and regional broadband seismic data to demonstrate that icebergs that calve from Jakobshavn Isbræ, Greenland, can generate ocean waves that are detectable over 150 km from their source. The waves, which are recorded seismically, have distinct spectral peaks, are not dispersive and persist for several hours. On the basis of these observations, we suggest that calving events at Jakobshavn Isbræ can stimulate seiches, or basin eigenmodes, in both Ilulissat Icefjord and Disko Bay. Our observations furthermore indicate that coastal, land-based seismometers located near calving termini (e.g. as part of the new Greenland Ice Sheet Monitoring Network (GLISN)) can aid investigations into the largely unexplored, oceanographic consequences of iceberg calving.