The Southern Uplands is a major Ordovician-Silurian accretionary terrane which developed as a marine basin over a period of c.75 Ma (495-420 Ma). The terrane extends to c. 10,000 km2 in Scotland alone and correlates with the similar-scale Longford–Down terrane in Ireland. Despite tectonic complexity, a detailed lithostratigraphy has been erected. The oldest strata are mudstones, cherts and lavas of mid-Arenig age known only in the Leadhills Imbricate Zone. The next youngest rocks are of similar lithology but of late Llanvirn-early Caradoc age. These oceanic sediments are succeeded by black shales of the Moffat Shale Group which are, in turn, diachronously overlain by huge volumes of turbiditic sandstones, siltstones, mudstones and minor conglomerates (greywackes) of Caradoc to Wenlock age. Overall, the terrane is sandstone-dominated, with other components such as lavas, volcaniclastics and cherts representing only a tiny proportion of the total volume. The conglomerates have a broadly northerly provenance, whereas the sandstones exhibit both marginal (NW and SE), and axial (NE and SW) derivation. During the Ordovician, strongly contrasting sources alternated through time. The youngest sandstones (Hawick and Riccarton groups), are notably rich in detrital biogenic carbonate, a rare component in the Leadhills Supergroup and Gala Group.

Ostracodes have a wide geographical distribution in the Ordovician of Scotland. They are known from the Southern Uplands, the Girvan district, the Highland Border region and the Inner Hebrides. Overall, more than forty species are recorded. They occur in clastic and carbonate rocks indicative of a range of shallow to deeper marine-shelf environments. Though many of the faunas are allochthonous, broad patterns of ostracode palaeoenvironmental distribution can be elucidated, and elements of the shallow marine Leperditella and open marineshelf Anisocyamus associations (previously recorded from N America) are present. Indigenous faunas are absent from the deep marine sediments of the Southern Uplands Northern Belt. Ostracodes are known from the Arenig, Llanvirn, Caradoc and Ashgill series in Scotland; those of the latter two series have widest biostratigraphical value. In the Girvan district the Caradoc species ‘Ctenobolbina’ ventrospinosa, Krausella variata, Balticella deckeri and Monoceratella teres have correlative value with N America, whilst the Ashgill species Kinnekullea comma appears to be a locum for the anceps graptolite Biozone in Britain, Ireland and possibly the eastern Baltic. The ostracodes are of typical Laurentian affinity, but show progressive generic links with the Baltic region during the late Llanvirn–Caradoc interval, and by Ashgill times display species-level links with southern Britain and Ireland. These distributional patterns suggest approaching geographical proximity for the early Palaeozoic continents of Laurentia, Baltica and Avalonia, and the ability of some Ordovician ostracodes to cross the Iapetus Ocean.

Leaching of Ordovician cherts from the Southern Uplands using dilute hydrofluoric acid has yielded numerous radiolaria, sponge spicules and a few conodonts. Although many of the radiolaria have suffered intense recrystallisation, it nevertheless proved possible to extract for SEM examination some examples with exquisitely preserved micro-structure. Despite this, the radiolaria have not proved sufficient, on their own, to answer the outstanding biostratigraphical question of one continuous or two separate episodes (Arenig and Llanvirn/Caradoc) of chert sedimentation in the Southern Uplands. This is partly because the biostratigraphy of Lower Palaeozoic radiolaria is still quite poorly known. A new radiolarian species, Protoceratoiciskum clarksoni Danelian, has been identified and described from cherts in the Crawford area. In addition, the distinctive sponge species Konyrium varium Nazarov & Popov, has also been found for the first time in Southern Uplands cherts. This new occurrence, in deep-water sediments, suggests a much wider habitat for this unusual sponge. Amongst the few conodont elements extracted, one can be identified as probably belonging to the genus Periodon.