VRO 42.05.01 (G166.0+4.3) is a SNR which has broken into and re-energized an old interstellar cavity. Observations of HI in a field containing the SNR show features associated with it. An expanding shell of mass ∼40 M⊙ is associated with the semi-circular shell of the SNR. The cavity, which the SNR has re-energized, is seen in the HI. A cloud of HI of mass ∼25 M⊙ has apparently been hit by the shock and has been accelerated by the post-shock flow.