A group of 150 Staphylococcus saprophyticus strains isolated from urinary tract infections in women were included in this study. Antimicrobial susceptibility tests showed that these isolates were sensitive to most antimicrobial agents. All strains were sensitive to penicillin. cephalothin. gentamicin. kanamvcin. trimethoprim and nitrofurantoin. Resistance to tetracycline was present in 10·6% of the strains. to chioramphenicol in 4 % to erythromycin in 1·3% and to streptomvcin in 1·3% All strains were resistant to cadmium chloride as well as to novobioein and nalidixic acid. Plasmid analysis showed that 8·2 % of the strains harboured plasmids, some of them with complex plasmid profiles.