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1668 results

Page 1 of 84

  • Utility of a pharmacist-managed Anticoagulation Program in patients with congenital heart disease

  • Meredith J. O’Neil, BreAnn N. Garr, Jenna M. Faircloth, Julie A. Ciambarella, Adam M. Lubert, Nicole L. Nelson, David S. Cooper
  • Journal: Cardiology in the Young , First View
  • Published online by Cambridge University Press: 08 September 2023, pp. 1-6
  • Background:

    Warfarin remains the preferred anticoagulant for many patients with CHD. The complexity of management led our centre to shift from a nurse-physician-managed model with many providers to a pharmacist-managed model with a centralized anticoagulation team. We aim to describe the patient cohort managed by our Anticoagulation Program and evaluate the impact of implementation of this consistent, pharmacist-managed model on time in therapeutic range, an evidence-based marker for clinical outcomes.

    Methods:

    A single-centre retrospective cohort study was conducted to evaluate the impact of the transition to a pharmacist-managed model to improve anticoagulation management at a tertiary pediatric heart centre. The percent time in therapeutic range for a cohort managed by both models was compared using a paired t-test. Patient characteristics and time in therapeutic range of the program were also described.

    Results:

    After implementing the pharmacist-managed model, the time in therapeutic range for a cohort of 58 patients increased from 65.7 to 80.2% (p < .001), and our Anticoagulation Program consistently maintained this improvement from 2013 to 2022. The cohort of patients managed by the Anticoagulation Program in 2022 included 119 patients with a median age of 24 years (range 19 months–69 years) with the most common indication for warfarin being mechanical valve replacement (n = 81, 68%).

    Conclusions:

    Through a practice change incorporating a collaborative, centralized, pharmacist-managed model, this cohort of CHD patients on warfarin had a fifteen percent increase in time in therapeutic range, which was sustained for nine years.

  • Changing stereotypes of partisans in the Trump Era

  • Ethan C. Busby, Adam J. Howat, C. Daniel Myers
  • Journal: Political Science Research and Methods , First View
  • Published online by Cambridge University Press: 24 August 2023, pp. 1-8
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  • Stereotypes of the two parties play an important role in political cognition, and a range of recent studies have examined the content and effects of partisan stereotypes. However, little work has studied change in partisan stereotypes over time. We address this question by comparing data on stereotypes of partisans collected before and after the Trump presidency, a time when we might expect individuals' images of the two parties to undergo significant change. Using a structural topic model, we compare responses to open-ended questions asking respondents to list words describing members of the two parties from 2016 and 2021. We find that partisan stereotypes in the 2021 sample are less group- and issue-based and focused more on personal traits. These results suggest that, during the Trump era, members of the mass public came to see the parties in more personalized, character-focused terms, potentially contributing to affective polarization.

  • Chapter 29 - Conclusions

  • from Part IV - Reception
  • Edited by J. N. Adams, All Souls College, Oxford, Anna Chahoud, Trinity College Dublin, Giuseppe Pezzini, Corpus Christi College, Oxford
  • Book: Early Latin
  • Published online: 27 July 2023
  • Print publication: 17 August 2023, pp 582-596

  • Summary

    Dividing the Latin language into neat chronological periods will not work without severe reservations. Usages that may seem to be ‘early’ often turn out not to be confined to a particular period, or alternatively their attestations may be genre-related, that is characteristic of a genre that happens to survive mainly from an early period. As for ancient grammarians and commentators on the language, no single concept of what early Latin is may be extracted from their works. Early Latin, or the Latin of ueteres, was a different thing for different commentators. One could use ‘early Latin’ (arbitrarily) of the Latin of the period before about 100 BC, provided that one excludes from the category ‘early’ usages which, though they were current early, also remained current beyond that time. Latin is attested over many centuries, and it was definitely not static. There was not however an entity ‘early Latin’ in use until a convenient date, which then changed into ‘classical Latin’. Recovery of early phenomena requires careful analysis of the distribution, comparative evidence across periods and genres, and a distinction between usage and fashion.

  • Chapter 14 - Early Latin Prayers and Aspects of Coordination

  • from Part III - Other Genres and Fragmentary Authors
  • Edited by J. N. Adams, All Souls College, Oxford, Anna Chahoud, Trinity College Dublin, Giuseppe Pezzini, Corpus Christi College, Oxford
  • Book: Early Latin
  • Published online: 27 July 2023
  • Print publication: 17 August 2023, pp 292-310

  • Summary

    This chapter examines aspects of coordination in the language of Latin prayers. The general question addressed concerns the sense in which early Latin features manifest themselves in prayers, and whether the term ‘early Latin’ is an appropriate designation of any peculiarities of prayer coordination. The results of the inquiry on ‘early’ prayers in the corpus considered in the chapter is that asyndeton bimembre, though in use, was not in high fashion, and that end-of-list coordination was preferred to long asyndeta and multiple coordinations, a preference that is the reverse of that of genres other than prayers in the early period and later.

Page 1 of 84